PLD3 epigenetic changes in the hippocampus of Alzheimer’s disease

Impact of late-onset Alzheimer’s genetic risk factors on beta-amyloid endocytic production

(2018) Cláudia Guimas Almeida et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Analysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein processing

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The effect of rare variants in TREM2 and PLD3 on longitudinal cognitive function in the Wisconsin Registry for Alzheimer's Prevention

(2018) Corinne D. Engelman et al.   NEUROBIOLOGY OF AGING

Unconventional Trafficking of Mammalian Phospholipase D3 to Lysosomes

(2018) Adriana Carolina Gonzalez et al.   Cell Reports

Genome-Wide DNA Methylation Differences Between Late-Onset Alzheimer's Disease and Cognitively Normal Controls in Human Frontal Cortex

(2018) Kelly M. Bakulski et al.   JOURNAL OF ALZHEIMERS DISEASE

Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes

(2017) Yoshinori Tanaka et al.   HUMAN MOLECULAR GENETICS

State of Play in Alzheimer’s Disease Genetics

(2017) Jin-Bao Zhu et al.   JOURNAL OF ALZHEIMERS DISEASE

PLD3 gene and processing of APP

(2017) Pietro Fazzari et al.   NATURE

Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer’s disease

(2016) Corey T. Watson et al.   Genome Medicine

TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer’s disease hippocampus

(2016) Naiara Celarain et al.   Clinical Epigenetics

Genes associated with Alzheimer's disease: an overview and current status

(2016) Mohan Giri et al.   Clinical Interventions in Aging

Rare Variants inPLD3Do Not Affect Risk for Early-Onset Alzheimer Disease in a European Consortium Cohort

(2015) Rita Cacace et al.   HUMAN MUTATION

PLD3 in Alzheimer’s Disease: a Modest Effect as Revealed by Updated Association and Expression Analyses

(2015) Deng-Feng Zhang et al.   MOLECULAR NEUROBIOLOGY

PLD3 variants in population studies

(2015) Sven J. van der Lee et al.   NATURE

PLD3 and sporadic Alzheimer's disease risk

(2015) Jean-Charles Lambert et al.   NATURE

PLD3 in non-familial Alzheimer's disease

(2015) Stefanie Heilmann et al.   NATURE

Association of Brain DNA Methylation inSORL1,ABCA7,HLA-DRB5,SLC24A4, andBIN1With Pathological Diagnosis of Alzheimer Disease

(2015) Lei Yu et al.   JAMA Neurology

The autophagy/lysosome pathway is impaired in SCA7 patients and SCA7 knock-in mice

(2014) Sandro Alves et al.   ACTA NEUROPATHOLOGICA

Promoter hypermethylation of the phosphatase DUSP22 mediates PKA-dependent TAU phosphorylation and CREB activation in Alzheimer's disease

(2014) Jose Vicente Sanchez-Mut et al.   HIPPOCAMPUS

Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

(2014) Katie Lunnon et al.   NATURE NEUROSCIENCE

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

(2014) Philip L De Jager et al.   NATURE NEUROSCIENCE

PLD3 is accumulated on neuritic plaques in Alzheimer’s disease brains

(2014) Jun-ichi Satoh et al.   Alzheimers Research & Therapy

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease

(2013) Carlos Cruchaga et al.   NATURE

Genetic insights in Alzheimer's disease

(2012) Karolien Bettens et al.   LANCET NEUROLOGY

Development of Purkinje cell degeneration in a knockin mouse model reveals lysosomal involvement in the pathogenesis of SCA6

(2012) T. Unno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Management of a twenty-first century brain bank: experience in the BrainNet Europe consortium

(2008) Jeanne E. Bell et al.   ACTA NEUROPATHOLOGICA

QUMA: quantification tool for methylation analysis

(2008) Y. Kumaki et al.   NUCLEIC ACIDS RESEARCH

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

(2008) W. S. Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA