Analysis of Hepatitis C Virus Decline during Treatment with the Protease Inhibitor Danoprevir Using a Multiscale Model
出版年份 2013 全文链接
标题
Analysis of Hepatitis C Virus Decline during Treatment with the Protease Inhibitor Danoprevir Using a Multiscale Model
作者
关键词
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出版物
PLoS Computational Biology
Volume 9, Issue 3, Pages e1002959
出版商
Public Library of Science (PLoS)
发表日期
2013-03-15
DOI
10.1371/journal.pcbi.1002959
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Modeling Quasispecies and Drug Resistance in Hepatitis C Patients Treated with a Protease Inhibitor
- (2012) Libin Rong et al. BULLETIN OF MATHEMATICAL BIOLOGY
- Anti−Hepatitis C Virus Drugs in Development
- (2012) Esperance A.K. Schaefer et al. GASTROENTEROLOGY
- Understanding silibinin’s modes of action against HCV using viral kinetic modeling
- (2012) Jeremie Guedj et al. JOURNAL OF HEPATOLOGY
- A Viral Dynamic Model for Treatment Regimens with Direct-acting Antivirals for Chronic Hepatitis C Infection
- (2012) Bambang S. Adiwijaya et al. PLoS Computational Biology
- Novel Therapies for Hepatitis C: Insights from the Structure of the Virus
- (2011) Dahlene N. Fusco et al. Annual Review of Medicine
- Virologic Escape during Danoprevir (ITMN-191/RG7227) Monotherapy Is Hepatitis C Virus Subtype Dependent and Associated with R155K Substitution
- (2011) Sharlene R. Lim et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Second-wave Protease Inhibitors: Choosing an Heir
- (2011) Sandra Ciesek et al. Clinics in Liver Disease
- 776 MODELING INTERFERON-ALPHA MEDIATED INHIBITION KINETICS OF INTRACELLULAR AND EXTRACELLULAR HCVRNA DURING HCV INFECTION IN VITRO
- (2011) H. Dahari et al. JOURNAL OF HEPATOLOGY
- Antiviral activity, safety, and pharmacokinetics of danoprevir/ritonavir plus PEG-IFN α-2a/RBV in hepatitis C patients
- (2011) Edward J. Gane et al. JOURNAL OF HEPATOLOGY
- Antiviral Activity of Danoprevir (ITMN-191/RG7227) in Combination With Pegylated Interferon α-2a and Ribavirin in Patients With Hepatitis C
- (2011) Nicole Forestier et al. JOURNAL OF INFECTIOUS DISEASES
- Boceprevir for Untreated Chronic HCV Genotype 1 Infection
- (2011) Fred Poordad et al. NEW ENGLAND JOURNAL OF MEDICINE
- Response-Guided Telaprevir Combination Treatment for Hepatitis C Virus Infection
- (2011) Kenneth E. Sherman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Boceprevir for Previously Treated Chronic HCV Genotype 1 Infection
- (2011) Bruce R. Bacon et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Comprehensive Hepatitis C Viral Kinetic Model Explaining Cure
- (2010) E Snoeck et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Protease Inhibitor–Resistant Hepatitis C Virus Mutants With Reduced Fitness From Impaired Production of Infectious Virus
- (2010) Tetsuro Shimakami et al. GASTROENTEROLOGY
- Pharmacodynamics of PEG-IFN-α-2a in HIV/HCV co-infected patients: Implications for treatment outcomes
- (2010) Harel Dahari et al. JOURNAL OF HEPATOLOGY
- Impact of peginterferon and ribavirin therapy on hepatocellular carcinoma: Incidence and survival in hepatitis C patients with advanced fibrosis
- (2010) Ana-Carolina Cardoso et al. JOURNAL OF HEPATOLOGY
- Treatment of chronic hepatitis C patients with the NS3/4A protease inhibitor danoprevir (ITMN-191/RG7227) leads to robust reductions in viral RNA: A phase 1b multiple ascending dose study
- (2010) Nicole Forestier et al. JOURNAL OF HEPATOLOGY
- Understanding hepatitis C viral dynamics with direct-acting antiviral agents due to the interplay between intracellular replication and cellular infection dynamics
- (2010) J. Guedj et al. JOURNAL OF THEORETICAL BIOLOGY
- A perspective on modelling hepatitis C virus infection
- (2010) J. Guedj et al. JOURNAL OF VIRAL HEPATITIS
- Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): a randomised, double-blind, placebo-controlled, dose-escalation trial
- (2010) Edward J Gane et al. LANCET
- Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect
- (2010) Min Gao et al. NATURE
- Rapid Emergence of Protease Inhibitor Resistance in Hepatitis C Virus
- (2010) L. Rong et al. Science Translational Medicine
- A Multi-Variant, Viral Dynamic Model of Genotype 1 HCV to Assess the in vivo Evolution of Protease-Inhibitor Resistant Variants
- (2010) Bambang S. Adiwijaya et al. PLoS Computational Biology
- Peginterferon alpha-2a is associated with higher sustained virological response than peginterferon alfa-2b in chronic hepatitis C: Systematic review of randomized trials
- (2009) Tahany Awad et al. HEPATOLOGY
- Modeling Subgenomic Hepatitis C Virus RNA Kinetics during Treatment with Alpha Interferon
- (2009) H. Dahari et al. JOURNAL OF VIROLOGY
- A Step Forward in Therapy for Hepatitis C
- (2009) Jay H. Hoofnagle NEW ENGLAND JOURNAL OF MEDICINE
- Telaprevir and Peginterferon with or without Ribavirin for Chronic HCV Infection
- (2009) Christophe Hézode et al. NEW ENGLAND JOURNAL OF MEDICINE
- Telaprevir with Peginterferon and Ribavirin for Chronic HCV Genotype 1 Infection
- (2009) John G. McHutchison et al. NEW ENGLAND JOURNAL OF MEDICINE
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