Growth Factor and Th2 Cytokine Signaling Pathways Converge at STAT6 to Promote Arginase Expression in Progressive Experimental Visceral Leishmaniasis

Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms

(2013) J. T. Mattila et al.   JOURNAL OF IMMUNOLOGY

The interactions and essential effects of intrinsic insulin-like growth factor-I onLeishmania (Leishmania) majorgrowth within macrophages

(2013) L. C. Reis et al.   PARASITE IMMUNOLOGY

Arginase Activity - A Marker of Disease Status in Patients with Visceral Leishmaniasis in Ethiopia

(2013) Tamrat Abebe et al.   PLoS Neglected Tropical Diseases

Reassessment of Immune Correlates in Human Visceral Leishmaniasis as Defined by Cytokine Release in Whole Blood

(2012) Om Prakash Singh et al.   Clinical and Vaccine Immunology

Insulin-like growth factor-I regulates the neonatal immune response in infection and maturation by suppression of IFN-γ

(2012) Alexander Puzik et al.   CYTOKINE

Arginase-1 expression in granulomas of tuberculosis patients: Figure 1

(2012) Ana P. Pessanha et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection

(2012) Fei Chen et al.   NATURE MEDICINE

Leishmaniasis Worldwide and Global Estimates of Its Incidence

(2012) Jorge Alvar et al.   PLoS One

The roles of receptor tyrosine kinases and their ligands in the wound repair process

(2012) Anna-Katharina Müller et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

FGF Receptor Inhibitors: Role in Cancer Therapy

(2012) Gennaro Daniele et al.   Current Oncology Reports

Local Increase of Arginase Activity in Lesions of Patients with Cutaneous Leishmaniasis in Ethiopia

(2012) Tamrat Abebe et al.   PLoS Neglected Tropical Diseases

Progressive Visceral Leishmaniasis Is Driven by Dominant Parasite-induced STAT6 Activation and STAT6-dependent Host Arginase 1 Expression

(2012) E. Yaneth Osorio et al.   PLoS Pathogens

Rhinovirus-induced basic fibroblast growth factor release mediates airway remodeling features

(2012) Chrysanthi L Skevaki et al.   Clinical and Translational Allergy

Compartment-Specific Remodeling of Splenic Micro-Architecture during Experimental Visceral Leishmaniasis

(2011) Pinar Yurdakul et al.   AMERICAN JOURNAL OF PATHOLOGY

Expression of IL-10-triggered STAT3-dependent IL-4Rα is required for induction of arginase 1 in visceral leishmaniasis

(2011) Arunima Biswas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Myeloid Cell IL-10 Production in Response to Leishmania Involves Inactivation of Glycogen Synthase Kinase-3  Downstream of Phosphatidylinositol-3 Kinase

(2011) D. Nandan et al.   JOURNAL OF IMMUNOLOGY

IL-10 Neutralization Promotes Parasite Clearance in Splenic Aspirate Cells From Patients With Visceral Leishmaniasis

(2011) Shalini Gautam et al.   JOURNAL OF INFECTIOUS DISEASES

mTOR signaling pathway regulates the IL-12/IL-10 axis in Leishmania donovani infection

(2011) Satyanarayana Swamy Cheekatla et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Interferon-Gamma Release Assay (Modified QuantiFERON) as a Potential Marker of Infection for Leishmania donovani, a Proof of Concept Study

(2011) Kamlesh Gidwani et al.   PLoS Neglected Tropical Diseases

Identification of Small Molecule Lead Compounds for Visceral Leishmaniasis Using a Novel Ex Vivo Splenic Explant Model System

(2011) Yaneth Osorio et al.   PLoS Neglected Tropical Diseases

IGF system in cancer

(2010) Jorge Chaves et al.   ANTI-CANCER DRUGS

Macrophages recruited via CCR2 produce insulin-like growth factor-1 to repair acute skeletal muscle injury

(2010) Haiyan Lu et al.   FASEB JOURNAL

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Inhibition of receptor tyrosine kinases restores immunocompetence and improves immune-dependent chemotherapy against experimental leishmaniasis in mice

(2010) Jane E. Dalton et al.   JOURNAL OF CLINICAL INVESTIGATION

Fibroblast Growth Factors: Biology, Function, and Application for Tissue Regeneration

(2010) Ye-Rang Yun et al.   Journal of Tissue Engineering

Cellular and molecular pathways linking inflammation and cancer

(2009) Chiara Porta et al.   IMMUNOBIOLOGY

Arginase in Parasitic Infections: Macrophage Activation, Immunosuppression, and Intracellular Signals

(2009) Cinthia C. Stempin et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Alternatively Activated and Immunoregulatory Monocytes in Human Filarial Infections

(2009) Subash Babu et al.   JOURNAL OF INFECTIOUS DISEASES

Local Suppression of T Cell Responses by Arginase-Induced L-Arginine Depletion in Nonhealing Leishmaniasis

(2009) Manuel Modolell et al.   PLoS Neglected Tropical Diseases

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Respiratory syncytial virus infection provokes airway remodelling in allergen-exposed mice in absence of prior allergen sensitization

(2008) S. Tourdot et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Coxiella burnetii, the agent of Q fever, stimulates an atypical M2 activation program in human macrophages

(2008) Marie Benoit et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Activation of PI3K/Akt signaling has a dominant negative effect on IL-12 production by macrophages infected with Leishmania amazonensis promastigotes

(2008) Aaron Ruhland et al.   EXPERIMENTAL PARASITOLOGY

Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives

(2008) Paulo C. Rodríguez et al.   IMMUNOLOGICAL REVIEWS

Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

(2008) Karim C El Kasmi et al.   NATURE IMMUNOLOGY

Type I IL-4Rs Selectively Activate IRS-2 to Induce Target Gene Expression in Macrophages

(2008) N. M. Heller et al.   Science Signaling