Progressive Visceral Leishmaniasis Is Driven by Dominant Parasite-induced STAT6 Activation and STAT6-dependent Host Arginase 1 Expression

Nutrient Transport and Pathogenesis in Selected Parasitic Protozoa

(2011) Scott M. Landfear   EUKARYOTIC CELL

Expression of IL-10-triggered STAT3-dependent IL-4Rα is required for induction of arginase 1 in visceral leishmaniasis

(2011) Arunima Biswas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inhibition profile of Leishmania mexicana arginase reveals differences with human arginase I

(2011) Eric Riley et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

IL-10 Neutralization Promotes Parasite Clearance in Splenic Aspirate Cells From Patients With Visceral Leishmaniasis

(2011) Shalini Gautam et al.   JOURNAL OF INFECTIOUS DISEASES

Leishmaniasis: complexity at the host–pathogen interface

(2011) Paul Kaye et al.   NATURE REVIEWS MICROBIOLOGY

Identification of Small Molecule Lead Compounds for Visceral Leishmaniasis Using a Novel Ex Vivo Splenic Explant Model System

(2011) Yaneth Osorio et al.   PLoS Neglected Tropical Diseases

Polyamine metabolism in Leishmania: from arginine to trypanothione

(2010) Gianni Colotti et al.   AMINO ACIDS

Duplex real-time reverse transcriptase PCR to determine cytokine mRNA expression in a hamster model of New World cutaneous leishmaniasis

(2010) Claudia M Espitia et al.   BMC IMMUNOLOGY

Determination of the cytokine profile in American cutaneous leishmaniasis using the polymerase chain reaction

(2010) G. CACERES-DITTMAR et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Arginine Usage in Mycobacteria-Infected Macrophages Depends on Autocrine-Paracrine Cytokine Signaling

(2010) J. E. Qualls et al.   Science Signaling

Recent advances in arginine metabolism: roles and regulation of the arginases

(2009) Sidney M Morris Jr   BRITISH JOURNAL OF PHARMACOLOGY

Arginase in Parasitic Infections: Macrophage Activation, Immunosuppression, and Intracellular Signals

(2009) Cinthia C. Stempin et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Autocrine IL-10 Induces Hallmarks of Alternative Activation in Macrophages and Suppresses Antituberculosis Effector Mechanisms without Compromising T Cell Immunity

(2009) T. Schreiber et al.   JOURNAL OF IMMUNOLOGY

Infection with Arginase-Deficient Leishmania major Reveals a Parasite Number-Dependent and Cytokine-Independent Regulation of Host Cellular Arginase Activity and Disease Pathogenesis

(2009) H. M. Muleme et al.   JOURNAL OF IMMUNOLOGY

Alternatively Activated and Immunoregulatory Monocytes in Human Filarial Infections

(2009) Subash Babu et al.   JOURNAL OF INFECTIOUS DISEASES

STAT6 activation by Toxoplasma gondii infection induces the expression of Th2 C-C chemokine ligands and B clade serine protease inhibitors in macrophage

(2009) Hye-Jin Ahn et al.   PARASITOLOGY RESEARCH

Proteophosophoglycans Regurgitated by Leishmania-Infected Sand Flies Target the L-Arginine Metabolism of Host Macrophages to Promote Parasite Survival

(2009) Matthew Rogers et al.   PLoS Pathogens

Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages

(2008) Sheila Donnelly et al.   FASEB JOURNAL

Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives

(2008) Paulo C. Rodríguez et al.   IMMUNOLOGICAL REVIEWS

Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

(2008) Karim C El Kasmi et al.   NATURE IMMUNOLOGY