Plasmodium falciparum Infection Induces Expression of a Mosquito Salivary Protein (Agaphelin) That Targets Neutrophil Function and Inhibits Thrombosis without Impairing Hemostasis

Desmolaris, a novel factor XIa anticoagulant from the salivary gland of the vampire bat (Desmodus rotundus) inhibits inflammation and thrombosis in vivo

(2013) D. Ma et al.   BLOOD

Thrombosis: tangled up in NETs

(2013) K. Martinod et al.   BLOOD

NETosis: how vital is it?

(2013) B. G. Yipp et al.   BLOOD

The potential of neutrophil elastase inhibitors as anti-inflammatory therapies

(2013) Peter A. Henriksen   CURRENT OPINION IN HEMATOLOGY

Platelets: bridging hemostasis, inflammation, and immunity

(2013) C. N. Jenne et al.   International Journal of Laboratory Hematology

Salivary Antigen-5/CAP Family Members Are Cu2+-dependent Antioxidant Enzymes That Scavenge O2⨪and Inhibit Collagen-induced Platelet Aggregation and Neutrophil Oxidative Burst

(2013) Teresa C. F. Assumpção et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycobacterium tuberculosis-Induced Neutrophil Extracellular Traps Activate Human Macrophages

(2013) Clara Braian et al.   Journal of Innate Immunity

Crossroads of coagulation and innate immunity: the case of deep vein thrombosis

(2013) C. Schulz et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Malaria biology and disease pathogenesis: insights for new treatments

(2013) Louis H Miller et al.   NATURE MEDICINE

Neutrophils—A Key Component of Ischemia-Reperfusion Injury

(2013) Zoe Victoria Schofield et al.   SHOCK

Pathophysiological role of neutrophils in acute myocardial infarction

(2013) Federico Carbone et al.   THROMBOSIS AND HAEMOSTASIS

Intracellular Secretory Leukoprotease Inhibitor Modulates Inositol 1,4,5-Triphosphate Generation and Exerts an Anti-Inflammatory Effect on Neutrophils of Individuals with Cystic Fibrosis and Chronic Obstructive Pulmonary Disease

(2013) Emer P. Reeves et al.   Biomed Research International

Ticks and tick-borne pathogens at the cutaneous interface: host defenses, tick countermeasures, and a suitable environment for pathogen establishment

(2013) Stephen Wikel   Frontiers in Microbiology

Lufaxin, a Novel Factor Xa Inhibitor From the Salivary Gland of the Sand Fly Lutzomyia longipalpis Blocks Protease-Activated Receptor 2 Activation and Inhibits Inflammation and Thrombosis In Vivo

(2012) Nicolas Collin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

In vivo roles of factor XII

(2012) T. Renne et al.   BLOOD

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

(2012) Marie-Luise von Brühl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A SerpinB1 Regulatory Mechanism Is Essential for Restricting Neutrophil Extracellular Trap Generation

(2012) Kalamo Farley et al.   JOURNAL OF IMMUNOLOGY

Phylogenetic distribution of protease inhibitors of the Kazal-family within the Arthropoda

(2012) Vincent van Hoef et al.   PEPTIDES

Maternal Malaria Induces a Procoagulant and Antifibrinolytic State That Is Embryotoxic but Responsive to Anticoagulant Therapy

(2012) John W. Avery et al.   PLoS One

Visualizing Non Infectious and Infectious Anopheles gambiae Blood Feedings in Naive and Saliva-Immunized Mice

(2012) Valerie Choumet et al.   PLoS One

Role of the endogenous elastase inhibitor, elafin, in cardiovascular injury

(2011) Shirjel R. Alam et al.   BIOCHEMICAL PHARMACOLOGY

A comprehensive gene expression atlas of sex- and tissue-specificity in the malaria vector, Anopheles gambiae

(2011) Dean A Baker et al.   BMC GENOMICS

Tissue factor pathway inhibitor: structure-function

(2011) George et al.   Frontiers in Bioscience-Landmark

Mechanisms underlying FeCl3-induced arterial thrombosis

(2011) A. ECKLY et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Towards a standardization of the murine ferric chloride-induced carotid arterial thrombosis model

(2011) A. P. OWENS III et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The neutrophil in vascular inflammation

(2011) Mia Phillipson et al.   NATURE MEDICINE

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

VectorBase: improvements to a bioinformatics resource for invertebrate vector genomics

(2011) K. Megy et al.   NUCLEIC ACIDS RESEARCH

Nitrophorin 2, a factor IX(a)-directed anticoagulant, inhibits arterial thrombosis without impairing haemostasis

(2011) Daniella M. Mizurini et al.   THROMBOSIS AND HAEMOSTASIS

Triplatin, a platelet aggregation inhibitor from the salivary gland of the triatomine vector of Chagas disease, binds to TXA2 but does notinteract with glycoprotein PVI

(2011) D. Ma et al.   THROMBOSIS AND HAEMOSTASIS

A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation

(2010) J. Chmelar et al.   BLOOD

Multiple structure alignment and consensus identification for proteins

(2010) Ivaylo Ilinkin et al.   BMC BIOINFORMATICS

Dipetalodipin, a Novel Multifunctional Salivary Lipocalin That Inhibits Platelet Aggregation, Vasoconstriction, and Angiogenesis through Unique Binding Specificity for TXA2, PGF2α, and 15(S)-HETE

(2010) Teresa C. F. Assumpção et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

(2010) F. H. Pilsczek et al.   JOURNAL OF IMMUNOLOGY

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

(2010) Rong Jin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neutrophils release brakes of coagulation

(2010) Wolfram Ruf et al.   NATURE MEDICINE

Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases

(2010) Steffen Massberg et al.   NATURE MEDICINE

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelet Activation by Extracellular Matrix Proteins in Haemostasis and Thrombosis

(2009) Steve Watson   CURRENT PHARMACEUTICAL DESIGN

A three-domain Kazal-type serine proteinase inhibitor exhibiting domain inhibitory and bacteriostatic activities from freshwater crayfish Procambarus clarkii

(2009) Xin-Cang Li et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Structure and function of invertebrate Kazal-type serine proteinase inhibitors

(2009) Vichien Rimphanitchayakit et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

IC50-to-Ki: a web-based tool for converting IC50 to Ki values for inhibitors of enzyme activity and ligand binding

(2009) R. Z. Cer et al.   NUCLEIC ACIDS RESEARCH

Platelet aggregation inhibitors from hematophagous animals

(2009) Ivo M.B. Francischetti   TOXICON

Platelet Chemokines in Vascular Disease

(2008) Christian A. Gleissner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS

Distinct Malaria Parasite Sporozoites Reveal Transcriptional Changes That Cause Differential Tissue Infection Competence in the Mosquito Vector and Mammalian Host

(2008) S. A. Mikolajczak et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanisms of Thrombus Formation

(2008) Bruce Furie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protein secondary structure analyses from circular dichroism spectroscopy: Methods and reference databases

(2007) Lee Whitmore et al.   BIOPOLYMERS