In vivo roles of factor XII

Polyphosphate: an ancient molecule that links platelets, coagulation, and inflammation

(2012) J. H. Morrissey et al.   BLOOD

Tissue factor-positive neutrophils bind to injured endothelial wall and initiate thrombus formation

(2012) R. Darbousset et al.   BLOOD

Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding

(2011) A. S. Revenko et al.   BLOOD

Polyphosphate is a cofactor for the activation of factor XI by thrombin

(2011) S. H. Choi et al.   BLOOD

Mast Cells Increase Vascular Permeability by Heparin-Initiated Bradykinin Formation In Vivo

(2011) Chris Oschatz et al.   IMMUNITY

Historical perspective and future direction of coagulation research

(2011) H. SAITO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The procoagulant and proinflammatory plasma contact system

(2011) Thomas Renné   Seminars in Immunopathology

The Plasma Contact System 2.0

(2011) Coen Maas et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo

(2010) Q. Cheng et al.   BLOOD

Factor XII stimulates ERK1/2 and Akt through uPAR, integrins, and the EGFR to initiate angiogenesis

(2010) G. A. LaRusch et al.   BLOOD

Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin

(2010) N. J. Mutch et al.   BLOOD

Factor XIIa Inhibitor Recombinant Human Albumin Infestin-4 Abolishes Occlusive Arterial Thrombus Formation Without Affecting Bleeding

(2010) Ina Hagedorn et al.   CIRCULATION

Coagulation in Vertebrates with a Focus on Evolution and Inflammation

(2010) Russell F. Doolittle   Journal of Innate Immunity

A 2-Step Mechanism of Arterial Thrombus Formation Induced by Human Atherosclerotic Plaques

(2010) Armin J. Reininger et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Ecallantide for the Treatment of Acute Attacks in Hereditary Angioedema

(2010) Marco Cicardi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nanofiltered C1 Inhibitor Concentrate for Treatment of Hereditary Angioedema

(2010) Bruce L. Zuraw et al.   NEW ENGLAND JOURNAL OF MEDICINE

Icatibant, a New Bradykinin-Receptor Antagonist, in Hereditary Angioedema

(2010) Marco Cicardi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Patients with severe factor XI deficiency have a reduced incidence of deep-vein thrombosis

(2010) Ophira Salomon et al.   THROMBOSIS AND HAEMOSTASIS

Clot-Inducing Minerals Versus Plasma Protein Dressing for Topical Treatment of External Bleeding in the Presence of Coagulopathy

(2010) Bijan Shams Kheirabadi et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Activated human platelets induce factor XIIa-mediated contact activation

(2009) Jennie Bäck et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dual role of collagen in factor XII-dependent thrombus formation

(2009) P. E. J. van der Meijden et al.   BLOOD

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL

Physiological responses to protein aggregates: Fibrinolysis, coagulation and inflammation (new roles for old factors)

(2009) Martijn F.B.G. Gebbink et al.   FEBS LETTERS

Polyphosphate and omptins: novel bacterial procoagulant agents

(2009) Thomas H. Yun et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Factor XI deficiency in humans

(2009) U. SELIGSOHN   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Extracellular histones are major mediators of death in sepsis

(2009) Jun Xu et al.   NATURE MEDICINE

Identification of fibronectin type I domains as amyloid-binding modules on tissue-type plasminogen activator and three homologs

(2008) Coen Maas et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Polyphosphate enhances fibrin clot structure

(2008) S. A. Smith et al.   BLOOD

Reduced incidence of ischemic stroke in patients with severe factor XI deficiency

(2008) O. Salomon et al.   BLOOD

Novel roles for factor XII-driven plasma contact activation system

(2008) Felicitas Müller et al.   CURRENT OPINION IN HEMATOLOGY

Coagulation factor XII (FXII) activity, activated FXII, distribution of FXII C46T gene polymorphism and coronary risk

(2008) J. BACH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A complete factor XII deficiency does not affect coagulopathy, inflammatory responses, and lethality, but attenuates early hypotension in endotoxemic mice

(2008) T. IWAKI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Evolution of the contact phase of vertebrate blood coagulation

(2008) M. B. PONCZEK et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events

(2008) Marco Guerrini et al.   NATURE BIOTECHNOLOGY

Heparin Comes Clean

(2008) Lawrence B. Schwartz   NEW ENGLAND JOURNAL OF MEDICINE

Hereditary Angioedema

(2008) Bruce L. Zuraw   NEW ENGLAND JOURNAL OF MEDICINE

Contaminated Heparin Associated with Adverse Clinical Events and Activation of the Contact System

(2008) Takashi Kei Kishimoto et al.   NEW ENGLAND JOURNAL OF MEDICINE