Brain Inositol Is a Novel Stimulator for Promoting Cryptococcus Penetration of the Blood-Brain Barrier

Cryptococcus neoformansphospholipase B1 activates host cell Rac1 for traversal across the blood-brain barrier

(2012) Ravi Maruvada et al.   CELLULAR MICROBIOLOGY

Cryptococcus neoformansActivates RhoGTPase Proteins Followed by Protein Kinase C, Focal Adhesion Kinase, and Ezrin to Promote Traversal across the Blood-Brain Barrier

(2012) Jong-Chul Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyaluronic Acid Receptor CD44 Deficiency Is Associated with Decreased Cryptococcus neoformansBrain Infection

(2012) Ambrose Jong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Capsule Independent Uptake of the Fungal Pathogen Cryptococcus neoformans into Brain Microvascular Endothelial Cells

(2012) Wilber Sabiiti et al.   PLoS One

Two Major Inositol Transporters and Their Role in Cryptococcal Virulence

(2011) Yina Wang et al.   EUKARYOTIC CELL

Invasion ofCryptococcus neoformansinto Human Brain Microvascular Endothelial Cells Is Mediated through the Lipid Rafts-Endocytic Pathway via the Dual Specificity Tyrosine Phosphorylation-regulated Kinase 3 (DYRK3)

(2011) Sheng-He Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cocaine Hijacks  1 Receptor to Initiate Induction of Activated Leukocyte Cell Adhesion Molecule: Implication for Increased Monocyte Adhesion and Migration in the CNS

(2011) H. Yao et al.   JOURNAL OF NEUROSCIENCE

Human Immunodeficiency Virus Infection of Human Astrocytes Disrupts Blood-Brain Barrier Integrity by a Gap Junction-Dependent Mechanism

(2011) E. A. Eugenin et al.   JOURNAL OF NEUROSCIENCE

Blood-brain barrier invasion by Cryptococcus neoformans is enhanced by functional interactions with plasmin

(2011) J. Stie et al.   MICROBIOLOGY-SGM

Phospholipids Trigger Cryptococcus neoformans Capsular Enlargement during Interactions with Amoebae and Macrophages

(2011) Cara J. Chrisman et al.   PLoS Pathogens

Mechanisms of Candida albicans Trafficking to the Brain

(2011) Yaoping Liu et al.   PLoS Pathogens

Clinical Practice Guidelines for the Management of Cryptococcal Disease: 2010 Update by the Infectious Diseases Society of America

(2010) John R. Perfect et al.   CLINICAL INFECTIOUS DISEASES

Survival Defects of Cryptococcus neoformans Mutants Exposed to Human Cerebrospinal Fluid Result in Attenuated Virulence in an Experimental Model of Meningitis

(2010) A. Lee et al.   INFECTION AND IMMUNITY

Cryptococci at the brain gate: break and enter or use a Trojan horse?

(2010) Arturo Casadevall   JOURNAL OF CLINICAL INVESTIGATION

Real-time imaging of trapping and urease-dependent transmigration of Cryptococcus neoformans in mouse brain

(2010) Meiqing Shi et al.   JOURNAL OF CLINICAL INVESTIGATION

Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

(2009) Benjamin J Park et al.   AIDS

How Sweet it is! Cell Wall Biogenesis and Polysaccharide Capsule Formation inCryptococcus neoformans

(2009) Tamara Lea Doering   Annual Review of Microbiology

Immortalized Human Brain Endothelial Cell Line HCMEC/D3 as a Model of the Blood-Brain Barrier Facilitates In Vitro Studies of Central Nervous System Infection byCryptococcus neoformans

(2009) Kiem Vu et al.   EUKARYOTIC CELL

Remodeling of Global Transcription Patterns ofCryptococcus neoformansGenes Mediated by the Stress-Activated HOG Signaling Pathways

(2009) Young-Joon Ko et al.   EUKARYOTIC CELL

Strategies for acquiring the phospholipid metabolite inositol in pathogenic bacteria, fungi and protozoa: making it and taking it

(2009) T. B. Reynolds   MICROBIOLOGY-SGM

Computational modeling and in silico analysis of differential regulation of myo-inositol catabolic enzymes in Cryptococcus neoformans

(2008) Emalee A Mackenzie et al.   BMC MOLECULAR BIOLOGY

Involvement of human CD44 during Cryptococcus neoformans infection of brain microvascular endothelial cells

(2008) Ambrose Jong et al.   CELLULAR MICROBIOLOGY

Invasion ofCryptococcus neoformansinto human brain microvascular endothelial cells requires protein kinase C-α activation

(2008) Ambrose Jong et al.   CELLULAR MICROBIOLOGY

PKC1Is Essential for Protection against both Oxidative and Nitrosative Stresses, Cell Integrity, and Normal Manifestation of Virulence Factors in the Pathogenic FungusCryptococcus neoformans

(2008) Kimberly J. Gerik et al.   EUKARYOTIC CELL

Epidemiology and management of cryptococcal meningitis: developments and challenges

(2008) Read Pukkila-Worley et al.   EXPERT OPINION ON PHARMACOTHERAPY

Candida albicans Uses Multiple Mechanisms To Acquire the Essential Metabolite Inositol during Infection

(2008) Y.-L. Chen et al.   INFECTION AND IMMUNITY

Evidence of a Role for Monocytes in Dissemination and Brain Invasion by Cryptococcus neoformans

(2008) C. Charlier et al.   INFECTION AND IMMUNITY