Productive Hepatitis C Virus Infection of Stem Cell-Derived Hepatocytes Reveals a Critical Transition to Viral Permissiveness during Differentiation

Use of human hepatocyte-like cells derived from induced pluripotent stem cells as a model for hepatocytes in hepatitis C virus infection

(2011) Takeshi Yoshida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mouse Hepatic Cells Support Assembly of Infectious Hepatitis C Virus Particles

(2011) Gang Long et al.   GASTROENTEROLOGY

A Humanized Mouse Model to Study Hepatitis C Virus Infection, Immune Response, and Liver Disease

(2011) Michael L. Washburn et al.   GASTROENTEROLOGY

A Feedback Loop Between the Liver-Enriched Transcription Factor Network and Mir-122 Controls Hepatocyte Differentiation

(2011) Ilaria Laudadio et al.   GASTROENTEROLOGY

Long-term propagation of serum hepatitis C virus (HCV) with production of enveloped HCV particles in human HepaRG hepatocytes

(2011) Ndiémé Ndongo-Thiam et al.   HEPATOLOGY

Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures

(2011) Svetlana Marukian et al.   HEPATOLOGY

Positive regulation of hepatic miR-122 expression by HNF4α

(2011) Zhen-Ya Li et al.   JOURNAL OF HEPATOLOGY

HepG2 Cells Expressing MicroRNA miR-122 Support the Entire Hepatitis C Virus Life Cycle

(2011) C. M. Narbus et al.   JOURNAL OF VIROLOGY

ISG56 and IFITM1 Proteins Inhibit Hepatitis C Virus Replication

(2011) A. Raychoudhuri et al.   JOURNAL OF VIROLOGY

Immunogenicity of induced pluripotent stem cells

(2011) Tongbiao Zhao et al.   NATURE

Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

(2011) Pengyu Huang et al.   NATURE

Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors

(2011) Sayaka Sekiya et al.   NATURE

EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

(2011) Joachim Lupberger et al.   NATURE MEDICINE

Modeling Disease in Human ESCs Using an Efficient BAC-Based Homologous Recombination System

(2010) Hoseok Song et al.   Cell Stem Cell

A Murine ESC-like State Facilitates Transgenesis and Homologous Recombination in Human Pluripotent Stem Cells

(2010) Christa Buecker et al.   Cell Stem Cell

Production of Infectious Hepatitis C Virus in Primary Cultures of Human Adult Hepatocytes

(2010) Philippe Podevin et al.   GASTROENTEROLOGY

Primary hepatocyte culture supports hepatitis C virus replication: A model for infection-associated hepatocarcinogenesis

(2010) Krishna Banaudha et al.   HEPATOLOGY

Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells

(2010) S. Tamir Rashid et al.   JOURNAL OF CLINICAL INVESTIGATION

Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment

(2010) Karl-Dimiter Bissig et al.   JOURNAL OF CLINICAL INVESTIGATION

Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors

(2010) Andrew J. Syder et al.   JOURNAL OF HEPATOLOGY

Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system

(2010) Christopher T Jones et al.   NATURE BIOTECHNOLOGY

Human hepatocyte transplantation: current experience and future challenges

(2010) Anil Dhawan et al.   Nature Reviews Gastroenterology & Hepatology

Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures

(2010) A. Ploss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

(2010) J. Hanna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of Liver Disease-Specific Induced Pluripotent Stem Cells Along with Efficient Differentiation to Functional Hepatocyte-Like Cells

(2010) Arefeh Ghodsizadeh et al.   Stem Cell Reviews and Reports

Persistent Growth of a Human Plasma-Derived Hepatitis C Virus Genotype 1b Isolate in Cell Culture

(2010) Erica Silberstein et al.   PLoS Pathogens

A Major Determinant of Cyclophilin Dependence and Cyclosporine Susceptibility of Hepatitis C Virus Identified by a Genetic Approach

(2010) Feng Yang et al.   PLoS Pathogens

A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus Replication

(2009) Andrew W. Tai et al.   Cell Host & Microbe

Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells

(2009) Zhihua Song et al.   CELL RESEARCH

Kinases required in hepatitis C virus entry and replication highlighted by small interference RNA screening

(2009) Maud Trotard et al.   FASEB JOURNAL

Visualizing Hepatitis C Virus Infections in Human Liver by Two-Photon Microscopy

(2009) Yuqiong Liang et al.   GASTROENTEROLOGY

The cyclophilin inhibitor Debio 025 combined with PEG IFNα2a significantly reduces viral load in treatment-naïve hepatitis C patients

(2009) Robert Flisiak et al.   HEPATOLOGY

Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

(2009) Karim Si-Tayeb et al.   HEPATOLOGY

Generation of functional human hepatic endoderm from human induced pluripotent stem cells

(2009) Gareth J. Sullivan et al.   HEPATOLOGY

Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development

(2009) Thomas Touboul et al.   HEPATOLOGY

Hepatitis C Virus NS2 Protein Contributes to Virus Particle Assembly via Opposing Epistatic Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes

(2009) T. Phan et al.   JOURNAL OF VIROLOGY

Short-hairpin RNAs delivered by lentiviral vector transduction trigger RIG-I-mediated IFN activation

(2009) Rachael Kenworthy et al.   NUCLEIC ACIDS RESEARCH

Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication

(2009) K. L. Berger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

HIV-1 entry inhibitors: an overview

(2009) Daniel R Kuritzkes   Current Opinion in HIV and AIDS

Production of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing Mutations

(2009) Thomas Pietschmann et al.   PLoS Pathogens

Development and characterization of hepatitis C virus genotype 1-7 cell culture systems: Role of CD81 and scavenger receptor class B type I and effect of antiviral drugs

(2008) Judith M. Gottwein et al.   HEPATOLOGY

Cyclophilin A Is an Essential Cofactor for Hepatitis C Virus Infection and the Principal Mediator of Cyclosporine Resistance In Vitro

(2008) F. Yang et al.   JOURNAL OF VIROLOGY

Efficient Differentiation of Functional Hepatocytes from Human Embryonic Stem Cells

(2008) Sadhana Agarwal et al.   STEM CELLS