Mapping the Genes for Susceptibility and Response to Leishmania tropica in Mouse

Dendritic Cell Differentiation State and Their Interaction with NKT Cells Determine Th1/Th2 Differentiation in the Murine Model of Leishmania major Infection

(2014) C. Wiethe et al.   JOURNAL OF IMMUNOLOGY

A Leishmania Ortholog of Macrophage Migration Inhibitory Factor Modulates Host Macrophage Responses

(2014) D. Kamir et al.   JOURNAL OF IMMUNOLOGY

IL-10 and TGF-  Control the Establishment of Persistent and Transmissible Infections Produced by Leishmania tropica in C57BL/6 Mice

(2014) C. F. Anderson et al.   JOURNAL OF IMMUNOLOGY

Arginine Transport Is Impaired in C57Bl/6 Mouse Macrophages as a Result of a Deletion in the Promoter of Slc7a2 (CAT2), and Susceptibility to Leishmania Infection Is Reduced

(2013) M. Gloria Sans-Fons et al.   JOURNAL OF INFECTIOUS DISEASES

Common variants in the HLA-DRB1–HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis

(2013) Michaela Fakiola et al.   NATURE GENETICS

Naturally Leishmania infantum-infected dogs display an overall impairment of chemokine and chemokine receptor expression during visceral leishmaniasis

(2013) Manuela S.L. Nascimento et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Molecular Diagnosis and Species Identification of Mucosal Leishmaniasis in Iran and Correlation with Cytological Findings

(2012) Sadegh Shirian et al.   ACTA CYTOLOGICA

RFLPs of ITS, ITS1 and hsp70 amplicons and sequencing of ITS1 of recent clinical isolates of Kala-azar from India and Bangladesh confirms the association of L. tropica with the disease

(2012) Supriya Khanra et al.   ACTA TROPICA

Disruption of the fusion of Leishmania parasitophorous vacuoles with ER vesicles results in the control of the infection

(2012) Johnathan Canton et al.   CELLULAR MICROBIOLOGY

Leishmaniasis: Prevention, Parasite Detection and Treatment

(2012) T. Kobets et al.   CURRENT MEDICINAL CHEMISTRY

Leishmania donovani: CD2 biased immune response skews the SAG mediated therapy for a predominant Th1 response in experimental infection

(2012) Sanjiva Bimal et al.   EXPERIMENTAL PARASITOLOGY

Wound healing genes and susceptibility to cutaneous leishmaniasis in Brazil

(2012) Léa Castellucci et al.   INFECTION GENETICS AND EVOLUTION

Host Genetics and Chlamydia Disease: Prediction and Validation of Disease Severity Mechanisms

(2012) Isao Miyairi et al.   PLoS One

Genetic Evidence of Functional Ficolin-2 Haplotype as Susceptibility Factor in Cutaneous Leishmaniasis

(2012) Amal Assaf et al.   PLoS One

Leishmaniasis Worldwide and Global Estimates of Its Incidence

(2012) Jorge Alvar et al.   PLoS One

Genetics of Host Response to Leishmania tropica in Mice – Different Control of Skin Pathology, Chemokine Reaction, and Invasion into Spleen and Liver

(2012) Tetyana Kobets et al.   PLoS Neglected Tropical Diseases

Disease Severity in Patients Infected with Leishmania mexicana Relates to IL-1β

(2012) Edith A. Fernández-Figueroa et al.   PLoS Neglected Tropical Diseases

Higher Expression of CCL2, CCL4, CCL5, CCL21, and CXCL8 Chemokines in the Skin Associated with Parasite Density in Canine Visceral Leishmaniasis

(2012) Daniel Menezes-Souza et al.   PLoS Neglected Tropical Diseases

Progressive Visceral Leishmaniasis Is Driven by Dominant Parasite-induced STAT6 Activation and STAT6-dependent Host Arginase 1 Expression

(2012) E. Yaneth Osorio et al.   PLoS Pathogens

Redundant Notch1 and Notch2 Signaling Is Necessary for IFNγ Secretion by T Helper 1 Cells During Infection with Leishmania major

(2012) Floriane Auderset et al.   PLoS Pathogens

Genetic and functional evaluation of the role of CXCR1 and CXCR2 in susceptibility to visceral leishmaniasis in north-east India

(2011) Sanjana Mehrotra et al.   BMC Medical Genetics

Evidence for epistasis between hemoglobin C and immune genes in human P. falciparum malaria: a family study in Burkina Faso

(2011) A Atkinson et al.   GENES AND IMMUNITY

FLI1 polymorphism affects susceptibility to cutaneous leishmaniasis in Brazil

(2011) L Castellucci et al.   GENES AND IMMUNITY

CD40 and tumour necrosis factor-α co-operate to up-regulate inducuble nitric oxide synthase expression in macrophages

(2011) Jose-Andres C. Portillo et al.   IMMUNOLOGY

TGFB1 and IL8 gene polymorphisms and susceptibility to visceral leishmaniasis

(2011) Amanda Farage Frade et al.   INFECTION GENETICS AND EVOLUTION

Genetic and Functional Evidence Implicating DLL1 as the Gene That Influences Susceptibility to Visceral Leishmaniasis at Chromosome 6q27

(2011) Michaela Fakiola et al.   JOURNAL OF INFECTIOUS DISEASES

Preparation of highly infective Leishmania promastigotes by cultivation on SNB-9 biphasic medium

(2011) Igor Grekov et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy

(2011) Furen Zhang et al.   NATURE GENETICS

Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species

(2011) Frédéric Raymond et al.   NUCLEIC ACIDS RESEARCH

Reappraisal of the immunopathogenesis of disseminated leishmaniasis: in situ and systemic immune response

(2011) Paulo R. Machado et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Genetic Control of Resistance to Trypanosoma brucei brucei Infection in Mice

(2011) Matyáš Šíma et al.   PLoS Neglected Tropical Diseases

CXCR1 and SLC11A1polymorphisms affect susceptibility to cutaneous leishmaniasis in Brazil: a case-control and family-based study

(2010) Léa Castellucci et al.   BMC Medical Genetics

Human mucosal leishmaniasis: Neutrophils infiltrate areas of tissue damage that express high levels of Th17-related cytokines

(2010) Viviane S. Boaventura et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Evaluation of localized and systemic immune responses in cutaneous leishmaniasis caused by Leishmania tropica: interleukin-8, monocyte chemotactic protein-1 and nitric oxide are major regulatory factors

(2010) Rajesh Kumar et al.   IMMUNOLOGY

Fine Mapping of Leishmania major Susceptibility Locus lmr2 and Evidence of a Role for Fli1 in Disease and Wound Healing

(2010) A. Sakthianandeswaren et al.   INFECTION AND IMMUNITY

The −2518bp promoter polymorphism at CCL2/MCP1 influences susceptibility to mucosal but not localized cutaneous leishmaniasis in Brazil

(2010) Rajendranath Ramasawmy et al.   INFECTION GENETICS AND EVOLUTION

IL-1-induced inflammation promotes development of leishmaniasis in susceptible BALB/c mice

(2010) E. Voronov et al.   INTERNATIONAL IMMUNOLOGY

Modulation of Dendritic Cell Responses by Parasites: A Common Strategy to Survive

(2010) César A. Terrazas et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Type I IFN Receptor Regulates Neutrophil Functions and Innate Immunity to Leishmania Parasites

(2010) L. Xin et al.   JOURNAL OF IMMUNOLOGY

Leishmania parasite detection and quantification using PCR-ELISA

(2010) Tetyana Kobets et al.   Nature Protocols

Missing heritability and strategies for finding the underlying causes of complex disease

(2010) Evan E. Eichler et al.   NATURE REVIEWS GENETICS

Transgenerational genetic effects

(2010) Vicki R Nelson et al.   Epigenomics

Leishmania-Induced Inactivation of the Macrophage Transcription Factor AP-1 Is Mediated by the Parasite Metalloprotease GP63

(2010) Irazú Contreras et al.   PLoS Pathogens

Loci controlling lymphocyte production of interferon γ after alloantigen stimulation in vitro and their co-localization with genes controlling lymphocyte infiltration of tumors and tumor susceptibility

(2009) Marie Lipoldová et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Distinct genetic control of parasite elimination, dissemination, and disease after Leishmania major infection

(2009) Iryna Kurey et al.   IMMUNOGENETICS

Clinical Chemistry of Congenic Mice with Quantitative Trait Loci for Predicted Responses to Trypanosoma congolense Infection

(2009) B. Rathkolb et al.   INFECTION AND IMMUNITY

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Leishmania GP63 Alters Host Signaling Through Cleavage-Activated Protein Tyrosine Phosphatases

(2009) M. A. Gomez et al.   Science Signaling

Mechanisms and consequences of persistence of intracellular pathogens: leishmaniasis as an example

(2008) Christian Bogdan   CELLULAR MICROBIOLOGY

Decreased IL-10 and IL-13 production and increased CD44hiT cell recruitment contribute toLeishmania majorimmunity induced by non-persistent parasites

(2008) Lukasz Kedzierski et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mouse to human comparative genetics reveals a novel immunoglobulin E-controlling locus on Hsa8q12

(2008) Elena S. Gusareva et al.   IMMUNOGENETICS

VCAM-1 and VLA-4 Modulate Dendritic Cell IL-12p40 Production in Experimental Visceral Leishmaniasis

(2008) Amanda C. Stanley et al.   PLoS Pathogens