The Spatiotemporal Program of DNA Replication Is Associated with Specific Combinations of Chromatin Marks in Human Cells

Bubble-seq analysis of the human genome reveals distinct chromatin-mediated mechanisms for regulating early- and late-firing origins

(2013) Larry D. Mesner et al.   GENOME RESEARCH

PcG-Mediated Higher-Order Chromatin Structures Modulate Replication Programs at the Drosophila BX-C

(2013) Federica Lo Sardo et al.   PLoS Genetics

New insights into replication origin characteristics in metazoans

(2012) Christelle Cayrou et al.   CELL CYCLE

Polycomb function during oogenesis is required for mouse embryonic development

(2012) E. Posfai et al.   GENES & DEVELOPMENT

The role of PR-Set7 in replication licensing depends on Suv4-20h

(2012) D. B. Beck et al.   GENES & DEVELOPMENT

Genome-wide mapping of human DNA-replication origins: Levels of transcription at ORC1 sites regulate origin selection and replication timing

(2012) G. I. Dellino et al.   GENOME RESEARCH

Genome-scale identification of active DNA replication origins

(2012) Christelle Cayrou et al.   METHODS

Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation

(2012) Tamir Chandra et al.   MOLECULAR CELL

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Multiscale analysis of genome-wide replication timing profiles using a wavelet-based signal-processing algorithm

(2012) Benjamin Audit et al.   Nature Protocols

Unraveling cell type–specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs

(2012) Emilie Besnard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Replication origins run (ultra) deep

(2012) David M Gilbert   NATURE STRUCTURAL & MOLECULAR BIOLOGY

USF Binding Sequences from the HS4 Insulator Element Impose Early Replication Timing on a Vertebrate Replicator

(2012) Vahideh Hassan-Zadeh et al.   PLOS BIOLOGY

Replication Fork Polarity Gradients Revealed by Megabase-Sized U-Shaped Replication Timing Domains in Human Cell Lines

(2012) Antoine Baker et al.   PLoS Computational Biology

Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems

(2011) Kim-Anh Lê Cao et al.   BMC BIOINFORMATICS

Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features

(2011) C. Cayrou et al.   GENOME RESEARCH

Mapping and analysis of chromatin state dynamics in nine human cell types

(2011) Jason Ernst et al.   NATURE

Evidence for Sequential and Increasing Activation of Replication Origins along Replication Timing Gradients in the Human Genome

(2011) Guillaume Guilbaud et al.   PLoS Computational Biology

Nucleotide supply, not local histone acetylation, sets replication origin usage in transcribed regions

(2010) Sophie Gay et al.   EMBO REPORTS

Impact of replication timing on non-CpG and CpG substitution rates in mammalian genomes

(2010) C. L. Chen et al.   GENOME RESEARCH

Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types

(2010) T. Ryba et al.   GENOME RESEARCH

Chromatin signatures of the Drosophila replication program

(2010) M. L. Eaton et al.   GENOME RESEARCH

The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells

(2010) Mathieu Tardat et al.   NATURE CELL BIOLOGY

Genome-wide approaches to determining origin distribution

(2009) Jean-Charles Cadoret et al.   CHROMOSOME RESEARCH

The Relationship between DNA Replication and Human Genome Organization

(2009) A. Necsulea et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genomic Study of Replication Initiation in Human Chromosomes Reveals the Influence of Transcription Regulation and Chromatin Structure on Origin Selection

(2009) Neerja Karnani et al.   MOLECULAR BIOLOGY OF THE CELL

Open chromatin encoded in DNA sequence is the signature of ‘master’ replication origins in human cells

(2009) Benjamin Audit et al.   NUCLEIC ACIDS RESEARCH

Sole-Search: an integrated analysis program for peak detection and functional annotation using ChIP-seq data

(2009) Kimberly R. Blahnik et al.   NUCLEIC ACIDS RESEARCH

Sequencing newly replicated DNA reveals widespread plasticity in human replication timing

(2009) R. S. Hansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells

(2009) Joana Sequeira-Mendes et al.   PLoS Genetics

DNA replication timing of the human  -globin domain is controlled by histone modification at the origin

(2008) A. Goren et al.   GENES & DEVELOPMENT

Polycomb Group Protein-associated Chromatin Is Reproduced in Post-mitotic G1Phase and Is Required for S Phase Progression

(2008) Takahiro Aoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A revisionist replicon model for higher eukaryotic genomes

(2008) J.L. Hamlin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Genome-wide studies highlight indirect links between human replication origins and gene regulation

(2008) J.-C. Cadoret et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication

(2008) Arkaitz Ibarra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation

(2008) Ichiro Hiratani et al.   PLOS BIOLOGY