KDM5 Interacts with Foxo to Modulate Cellular Levels of Oxidative Stress

Reactive Oxygen Species: Stuck in the Middle of Neurodegeneration

(2017) David A. Patten et al.   JOURNAL OF ALZHEIMERS DISEASE

Interpreting the language of histone and DNA modifications

(2014) Scott B. Rothbart et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Oxidative Stress, Redox Signaling and Cancer Chemoresistance: Putting Together the Pieces of the Puzzle

(2014) Vanessa Victorino et al.   CURRENT MEDICINAL CHEMISTRY

The Histone-H3K4-Specific Demethylase KDM5B Binds to Its Substrate and Product through Distinct PHD Fingers

(2014) Brianna J. Klein et al.   Cell Reports

Histone Demethylase RBP2 Is Critical for Breast Cancer Progression and Metastasis

(2014) Jian Cao et al.   Cell Reports

Current overview of functions of FoxO proteins, with special regards to cellular homeostasis, cell response to stress, as well as inflammation and aging

(2013) M Wątroba et al.   Advances in Medical Sciences

H3K4 demethylase activities repress proliferative and postmitotic aging

(2013) Stacy M. Alvares et al.   AGING CELL

Involvement of Redox State in the Aging of Drosophila melanogaster

(2013) William C. Orr et al.   ANTIOXIDANTS & REDOX SIGNALING

Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells

(2013) Alexander Roesch et al.   CANCER CELL

Multiple roles of Nrf2-Keap1 signaling

(2013) Huai Deng   FLY

Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers

(2013) Xinyuan Li et al.   Journal of Hematology & Oncology

DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity

(2013) Christian G. Riedel et al.   NATURE CELL BIOLOGY

Myc-Dependent Genome Instability and Lifespan in Drosophila

(2013) Christina Greer et al.   PLoS One

Balancing of Histone H3K4 Methylation States by the Kdm5c/SMCX Histone Demethylase Modulates Promoter and Enhancer Function

(2013) Nikolay S. Outchkourov et al.   Cell Reports

The Histone Demethylase Jarid1b Ensures Faithful Mouse Development by Protecting Developmental Genes from Aberrant H3K4me3

(2013) Mareike Albert et al.   PLoS Genetics

Activin Signaling Targeted by Insulin/dFOXO Regulates Aging and Muscle Proteostasis in Drosophila

(2013) Hua Bai et al.   PLoS Genetics

The role of oxidative stress in Rett syndrome: an overview

(2012) Claudio De Felice et al.   Annals of the New York Academy of Sciences

Mitochondria and Organismal Longevity

(2012) Ara B. Hwang et al.   CURRENT GENOMICS

Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease

(2012) Michael H. Yan et al.   FREE RADICAL BIOLOGY AND MEDICINE

dKDM5/LID regulates H3K4me3 dynamics at the transcription-start site (TSS) of actively transcribed developmental genes

(2012) Marta Lloret-Llinares et al.   NUCLEIC ACIDS RESEARCH

NAD+metabolism and oxidative stress: the golden nucleotide on a crown of thorns

(2012) Hassina Massudi et al.   REDOX REPORT

dFOXO-independent effects of reduced insulin-like signaling inDrosophila

(2011) Cathy Slack et al.   AGING CELL

Regulation of FoxO transcription factors by acetylation and protein–protein interactions

(2011) Hiroaki Daitoku et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Hormone-Dependent Module Regulating Energy Balance

(2011) Biao Wang et al.   CELL

Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis

(2011) Maria M. Mihaylova et al.   CELL

Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling

(2011) N. Alic et al.   Molecular Systems Biology

A novel nonsense mutation in KDM5C/JARID1C gene causing intellectual disability, short stature and speech delay

(2011) Cíntia B. Santos-Rebouças et al.   NEUROSCIENCE LETTERS

Genome-wide chromatin occupancy analysis reveals a role for ASH2 in transcriptional pausing

(2011) Sílvia Pérez-Lluch et al.   NUCLEIC ACIDS RESEARCH

Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

(2011) W. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone Lysine Demethylase JARID1a Activates CLOCK-BMAL1 and Influences the Circadian Clock

(2011) L. DiTacchio et al.   SCIENCE

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer

(2011) Lauren P. Blair et al.   Cancers

Neuroprotective effect of peroxiredoxin 6 against hypoxia-induced retinal ganglion cell damage

(2010) Rajkumar Tulsawani et al.   BMC NEUROSCIENCE

A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth

(2010) Alexander Roesch et al.   CELL

Activation of FoxO by LRRK2 induces expression of proapoptotic proteins and alters survival of postmitotic dopaminergic neuron in Drosophila

(2010) Tomoko Kanao et al.   HUMAN MOLECULAR GENETICS

Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans

(2010) Eric L. Greer et al.   NATURE

Chromatin structure and the inheritance of epigenetic information

(2010) Raphaël Margueron et al.   NATURE REVIEWS GENETICS

Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides

(2010) Sebastian Grönke et al.   PLoS Genetics

Essential Functions of the Histone Demethylase Lid

(2010) Ling Li et al.   PLoS Genetics

Peroxiredoxin 5 confers protection against oxidative stress and apoptosis and also promotes longevity inDrosophila

(2009) Svetlana N. Radyuk et al.   BIOCHEMICAL JOURNAL

4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila

(2009) Brian M. Zid et al.   CELL

Identification and characterization of two novel JARID1C mutations: suggestion of an emerging genotype–phenotype correlation

(2009) Sinitdhorn Rujirabanjerd et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger

(2009) Gang G. Wang et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Drosophila lifespan control by dietary restriction independent of insulin-like signaling

(2008) Kyung-Jin Min et al.   AGING CELL

Nutritional Control of Protein Biosynthetic Capacity by Insulin via Myc in Drosophila

(2008) Aurelio A. Teleman et al.   Cell Metabolism

The H3K4 Demethylase Lid Associates with and Inhibits Histone Deacetylase Rpd3

(2008) N. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

Genome-wide Analysis of the H3K4 Histone Demethylase RBP2 Reveals a Transcriptional Program Controlling Differentiation

(2008) Nuria Lopez-Bigas et al.   MOLECULAR CELL

GOEAST: a web-based software toolkit for Gene Ontology enrichment analysis

(2008) Qi Zheng et al.   NUCLEIC ACIDS RESEARCH

The FoxO code

(2008) D R Calnan et al.   ONCOGENE

Sex-Specific Expression of the X-Linked Histone Demethylase Gene Jarid1c in Brain

(2008) Jun Xu et al.   PLoS One