Hypersensitivity of Primordial Germ Cells to Compromised Replication-Associated DNA Repair Involves ATM-p53-p21 Signaling

Reversal of Female Infertility by Chk2 Ablation Reveals the Oocyte DNA Damage Checkpoint Pathway

(2014) E. Bolcun-Filas et al.   SCIENCE

Mutations in ERCC4, Encoding the DNA-Repair Endonuclease XPF, Cause Fanconi Anemia

(2013) Massimo Bogliolo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Malfunction of Nuclease ERCC1-XPF Results in Diverse Clinical Manifestations and Causes Cockayne Syndrome, Xeroderma Pigmentosum, and Fanconi Anemia

(2013) Kazuya Kashiyama et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The REV7 Subunit of DNA Polymerase ζ Is Essential for Primordial Germ Cell Maintenance in the Mouse

(2013) Naoki Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Missense Mutation inRev7Disrupts Formation of Polζ, Impairing Mouse Development and Repair of Genotoxic Agent-induced DNA Lesions

(2013) Maryam Khalaj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The MCM8-MCM9 Complex Promotes RAD51 Recruitment at DNA Damage Sites To Facilitate Homologous Recombination

(2013) J. Park et al.   MOLECULAR AND CELLULAR BIOLOGY

FANCM and FAAP24 Maintain Genome Stability via Cooperative as Well as Unique Functions

(2013) Yucai Wang et al.   MOLECULAR CELL

The DNA Translocase FANCM/MHF Promotes Replication Traverse of DNA Interstrand Crosslinks

(2013) Jing Huang et al.   MOLECULAR CELL

HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis

(2013) Carrie A. Adelman et al.   NATURE

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

(2013) Molly C. Kottemann et al.   NATURE

Helq acts in parallel to Fancc to suppress replication-associated genome instability

(2013) Spencer W. Luebben et al.   NUCLEIC ACIDS RESEARCH

DNA Damage Response: Three Levels of DNA Repair Regulation

(2013) B. M. Sirbu et al.   Cold Spring Harbor Perspectives in Biology

Human DNA helicase HELQ participates in DNA interstrand crosslink tolerance with ATR and RAD51 paralogs

(2013) Kei-ichi Takata et al.   Nature Communications

Overcoming reprogramming resistance of Fanconi anemia cells

(2012) L. U. W. Muller et al.   BLOOD

Bone Marrow Failure in Fanconi Anemia Is Triggered by an Exacerbated p53/p21 DNA Damage Response that Impairs Hematopoietic Stem and Progenitor Cells

(2012) Raphael Ceccaldi et al.   Cell Stem Cell

Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway

(2012) H. Kim et al.   GENES & DEVELOPMENT

The DNA translocase activity of FANCM protects stalled replication forks

(2012) Andrew N. Blackford et al.   HUMAN MOLECULAR GENETICS

MCM8- and MCM9-Deficient Mice Reveal Gametogenesis Defects and Genome Instability Due to Impaired Homologous Recombination

(2012) Malik Lutzmann et al.   MOLECULAR CELL

Mcm8 and Mcm9 Form a Complex that Functions in Homologous Recombination Repair Induced by DNA Interstrand Crosslinks

(2012) Kohei Nishimura et al.   MOLECULAR CELL

The Fanconi Anemia Ortholog FANCM Ensures Ordered Homologous Recombination in Both Somatic and Meiotic Cells inArabidopsis

(2012) Alexander Knoll et al.   PLANT CELL

The Fission Yeast FANCM Ortholog Directs Non-Crossover Recombination During Meiosis

(2012) A. Lorenz et al.   SCIENCE

FANCM Limits Meiotic Crossovers

(2012) W. Crismani et al.   SCIENCE

The structure of the FANCM–MHF complex reveals physical features for functional assembly

(2012) Yuyong Tao et al.   Nature Communications

Human MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway

(2011) Min Huang et al.   DNA REPAIR

Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression

(2011) Peter Bouwman et al.   JOURNAL OF PATHOLOGY

Fancf-deficient mice are prone to develop ovarian tumours

(2011) Sietske T Bakker et al.   JOURNAL OF PATHOLOGY

Variation in genome-wide mutation rates within and between human families

(2011) Donald F Conrad et al.   NATURE GENETICS

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

(2011) Gerry P Crossan et al.   NATURE GENETICS

Minichromosome maintenance helicase paralog MCM9 is dispensible for DNA replication but functions in germ-line stem cells and tumor suppression

(2011) S. A. Hartford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence that Meiotic Sex Chromosome Inactivation Is Essential for Male Fertility

(2010) Hélène Royo et al.   CURRENT BIOLOGY

Primordial germ cell proliferation is impaired in Fused Toes mutant embryos

(2010) Bongki Kim et al.   DEVELOPMENTAL BIOLOGY

Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors

(2010) Igor Landais et al.   Molecular Cancer

Sex Reversal in Zebrafish fancl Mutants Is Caused by Tp53-Mediated Germ Cell Apoptosis

(2010) Adriana Rodríguez-Marí et al.   PLoS Genetics

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M

(2009) Sietske T. Bakker et al.   HUMAN MOLECULAR GENETICS

The Fanconi Anemia Protein FANCM Is Controlled by FANCD2 and the ATR/ATM Pathways

(2009) Alexandra Sobeck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mouse models of Fanconi anemia

(2009) Kalindi Parmar et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Fanconi anemia and its diagnosis

(2009) Arleen D. Auerbach   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells

(2009) Ángel Raya et al.   NATURE

The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair

(2009) P. Knipscheer et al.   SCIENCE

Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24

(2008) J. M. Kim et al.   BLOOD

The Fanconi Anemia Protein FANCM Can Promote Branch Migration of Holliday Junctions and Replication Forks

(2008) Kerstin Gari et al.   MOLECULAR CELL