Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

Overcoming reprogramming resistance of Fanconi anemia cells

(2012) L. U. W. Muller et al.   BLOOD

A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2

(2012) Katharina Schlacher et al.   CANCER CELL

Bone Marrow Failure in Fanconi Anemia Is Triggered by an Exacerbated p53/p21 DNA Damage Response that Impairs Hematopoietic Stem and Progenitor Cells

(2012) Raphael Ceccaldi et al.   Cell Stem Cell

Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair

(2012) Koichi Sato et al.   EMBO JOURNAL

Quantitative Live Cell Imaging Reveals a Gradual Shift between DNA Repair Mechanisms and a Maximal Use of HR in Mid S Phase

(2012) Ketki Karanam et al.   MOLECULAR CELL

BRCA1 Functions Independently of Homologous Recombination in DNA Interstrand Crosslink Repair

(2012) Samuel F. Bunting et al.   MOLECULAR CELL

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function

(2012) Juan I. Garaycoechea et al.   NATURE

FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair

(2012) Weibin Zhou et al.   NATURE GENETICS

Repair of cisplatin-induced DNA interstrand crosslinks by a replication-independent pathway involving transcription-coupled repair and translesion synthesis

(2012) Milica Enoiu et al.   NUCLEIC ACIDS RESEARCH

DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI

(2012) K. Sato et al.   NUCLEIC ACIDS RESEARCH

How high are carrier frequencies of rare recessive syndromes? Contemporary estimates for Fanconi Anemia in the United States and Israel

(2011) Philip S. Rosenberg et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Double-Strand Break End Resection and Repair Pathway Choice

(2011) Lorraine S. Symington et al.   Annual Review of Genetics

Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11

(2011) Katharina Schlacher et al.   CELL

Human SNM1A and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair

(2011) A. T. Wang et al.   GENES & DEVELOPMENT

Functional and physical interaction between the mismatch repair and FA-BRCA pathways

(2011) Stacy A. Williams et al.   HUMAN MOLECULAR GENETICS

Aberrant chromosome morphology in human cells defective for Holliday junction resolution

(2011) Thomas Wechsler et al.   NATURE

Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice

(2011) Frédéric Langevin et al.   NATURE

SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype

(2011) Chantal Stoepker et al.   NATURE GENETICS

Mutations of the SLX4 gene in Fanconi anemia

(2011) Yonghwan Kim et al.   NATURE GENETICS

Mutations in BRIP1 confer high risk of ovarian cancer

(2011) Thorunn Rafnar et al.   NATURE GENETICS

Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway

(2011) Ivan V Rosado et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing

(2011) T. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of RAD51-Dependent DNA Interstrand Cross-Link Repair

(2011) D. T. Long et al.   SCIENCE

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage

(2010) A. Tulpule et al.   BLOOD

Identification of KIAA1018/FAN1, a DNA Repair Nuclease Recruited to DNA Damage by Monoubiquitinated FANCD2

(2010) Craig MacKay et al.   CELL

Deficiency of FANCD2-Associated Nuclease KIAA1018/FAN1 Sensitizes Cells to Interstrand Crosslinking Agents

(2010) Katja Kratz et al.   CELL

Cytokinesis failure occurs in Fanconi anemia pathway–deficient murine and human bone marrow hematopoietic cells

(2010) Patrizia Vinciguerra et al.   JOURNAL OF CLINICAL INVESTIGATION

A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair

(2010) Agata Smogorzewska et al.   MOLECULAR CELL

Preventing Nonhomologous End Joining Suppresses DNA Repair Defects of Fanconi Anemia

(2010) Adele Adamo et al.   MOLECULAR CELL

Mutation of the RAD51C gene in a Fanconi anemia–like disorder

(2010) Fiona Vaz et al.   NATURE GENETICS

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

(2010) Alfons Meindl et al.   NATURE GENETICS

Ku70 Corrupts DNA Repair in the Absence of the Fanconi Anemia Pathway

(2010) P. Pace et al.   SCIENCE

FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand Cross-Link Repair

(2010) T. Liu et al.   SCIENCE

Mammalian BTBD12/SLX4 Assembles A Holliday Junction Resolvase and Is Required for DNA Repair

(2009) Jennifer M. Svendsen et al.   CELL

Human SLX4 Is a Holliday Junction Resolvase Subunit that Binds Multiple DNA Repair/Recombination Endonucleases

(2009) Samira Fekairi et al.   CELL

Inactivation of Murine Usp1 Results in Genomic Instability and a Fanconi Anemia Phenotype

(2009) Jung Min Kim et al.   DEVELOPMENTAL CELL

XPF-ERCC1 Participates in the Fanconi Anemia Pathway of Cross-Link Repair

(2009) N. Bhagwat et al.   MOLECULAR AND CELLULAR BIOLOGY

Drosophila MUS312 and the Vertebrate Ortholog BTBD12 Interact with DNA Structure-Specific Endonucleases in DNA Repair and Recombination

(2009) Sabrina L. Andersen et al.   MOLECULAR CELL

Recruitment of Fanconi Anemia and Breast Cancer Proteins to DNA Damage Sites Is Differentially Governed by Replication

(2009) Xi Shen et al.   MOLECULAR CELL

Coordination of Structure-Specific Nucleases by Human SLX4/BTBD12 Is Required for DNA Repair

(2009) Ivan M. Muñoz et al.   MOLECULAR CELL

Acetaldehyde stimulates FANCD2 monoubiquitination, H2AX phosphorylation, and BRCA1 phosphorylation in human cells in vitro: Implications for alcohol-related carcinogenesis

(2009) Cheryl Marietta et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Fanconi anemia proteins and endogenous stresses

(2009) Qishen Pang et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Fanconi anemia and its diagnosis

(2009) Arleen D. Auerbach   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells

(2009) Ángel Raya et al.   NATURE

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis

(2009) Kok Lung Chan et al.   NATURE CELL BIOLOGY

Ku86 represses lethal telomere deletion events in human somatic cells

(2009) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair

(2009) P. Knipscheer et al.   SCIENCE

Mechanism of Replication-Coupled DNA Interstrand Crosslink Repair

(2008) Markus Räschle et al.   CELL

Mechanistic Insight into Site-Restricted Monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI

(2008) Arno F. Alpi et al.   MOLECULAR CELL

C. elegans: A model of Fanconi anemia and ICL repair

(2008) Jillian L. Youds et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway

(2008) Masamichi Ishiai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY