Epigenetic Upregulation of lncRNAs at 13q14.3 in Leukemia Is Linked to the In Cis Downregulation of a Gene Cluster That Targets NF-kB

TCL1A and ATM are co-expressed in chronic lymphocytic leukemia cells without deletion of 11q

(2012) A. Garding et al.   HAEMATOLOGICA

miR-16 Targets Transcriptional Corepressor SMRT and Modulates NF-kappaB-Regulated Transactivation of Interleukin-8 Gene

(2012) Rui Zhou et al.   PLoS One

In-vivo quantification of primary microRNA processing by Drosha with a luciferase based system

(2011) Danilo Allegra et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRIM13 regulates ER stress induced autophagy and clonogenic ability of the cells

(2011) Dhanendra Tomar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Functional dissection of the chromosome 13q14 tumor-suppressor locus using transgenic mouse lines

(2011) M. Lia et al.   BLOOD

Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia

(2011) D. Sampath et al.   BLOOD

Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML

(2011) M. B. Treppendahl et al.   BLOOD

Tcl1 interacts with Atm and enhances NF- B activation in hematologic malignancies

(2011) E. Gaudio et al.   BLOOD

Self-Renewing Hematopoietic Stem Cell Is the Primary Target in Pathogenesis of Human Chronic Lymphocytic Leukemia

(2011) Yoshikane Kikushige et al.   CANCER CELL

No-Nonsense Functions for Long Noncoding RNAs

(2011) Takashi Nagano et al.   CELL

The Prognostic Significance of Various 13q14 Deletions in Chronic Lymphocytic Leukemia

(2011) P. Ouillette et al.   CLINICAL CANCER RESEARCH

Active chromatin and noncoding RNAs: an intimate relationship

(2011) Ryan A Flynn et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

(2011) Víctor Quesada et al.   NATURE GENETICS

SF3B1and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia

(2011) Lili Wang et al.   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-κB and TGF-β signaling pathways

(2011) I Keklikoglou et al.   ONCOGENE

Coding RNAs with a non-coding function: Maintenance of open chromatin structure

(2011) Maïwen Caudron-Herger et al.   Nucleus

The lymph node microenvironment promotes B-cell receptor signaling, NF- B activation, and tumor proliferation in chronic lymphocytic leukemia

(2010) Y. Herishanu et al.   BLOOD

13q14 deletions in CLL involve cooperating tumor suppressors

(2010) A. Palamarchuk et al.   BLOOD

All You Need Is a Mir-acle: The Role of Nontranslated RNAs in the Suppression of B Cell Chronic Lymphocytic Leukemia

(2010) Peter Lichter   CANCER CELL

The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia

(2010) Ulf Klein et al.   CANCER CELL

Long Noncoding RNAs with Enhancer-like Function in Human Cells

(2010) Ulf Andersson Ørom et al.   CELL

Characterization of the RNA content of chromatin

(2010) T. Mondal et al.   GENOME RESEARCH

Large non-coding RNAs: missing links in cancer?

(2010) M. Huarte et al.   HUMAN MOLECULAR GENETICS

MicroRNAs modulate the noncanonical transcription factor NF-κB pathway by regulating expression of the kinase IKKα during macrophage differentiation

(2010) Tao Li et al.   NATURE IMMUNOLOGY

MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma

(2009) A. M. Roccaro et al.   BLOOD

A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster

(2009) X. Zhang et al.   BLOOD

miR-15a and miR-16 Are Implicated in Cell Cycle Regulation in a Rb-Dependent Manner and Are Frequently Deleted or Down-regulated in Non–Small Cell Lung Cancer

(2009) Nora Bandi et al.   CANCER RESEARCH

Evolution and Functions of Long Noncoding RNAs

(2009) Chris P. Ponting et al.   CELL

DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

(2009) Mikael Lerner et al.   EXPERIMENTAL CELL RESEARCH

The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing

(2009) M. J. Gamble et al.   GENES & DEVELOPMENT

Chronic lymphocytic leukemia and 13q14: miRs and more

(2009) Daniel Mertens et al.   LEUKEMIA & LYMPHOMA

Long non-coding RNAs: insights into functions

(2009) Tim R. Mercer et al.   NATURE REVIEWS GENETICS

Regulatory roles of natural antisense transcripts

(2009) Mohammad Ali Faghihi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia

(2009) S.-S. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Human Retinoblastoma Gene Is Imprinted

(2009) Deniz Kanber et al.   PLoS Genetics

The NF- B subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target

(2008) S. Hewamana et al.   BLOOD

Molecular allelokaryotyping of early-stage, untreated chronic lymphocytic leukemia

(2008) Sören Lehmann et al.   CANCER

Integrated Genomic Profiling of Chronic Lymphocytic Leukemia Identifies Subtypes of Deletion 13q14

(2008) P. Ouillette et al.   CANCER RESEARCH

The Novel Nuclear Factor- B Inhibitor LC-1 Is Equipotent in Poor Prognostic Subsets of Chronic Lymphocytic Leukemia and Shows Strong Synergy with Fludarabine

(2008) S. Hewamana et al.   CLINICAL CANCER RESEARCH

Differential Role of the Transcription Factor NF-κB in Selection and Survival of CD4+ and CD8+ Thymocytes

(2008) Eijiro Jimi et al.   IMMUNITY

Bone marrow fibroblasts induce expression of PI3K/NF-κB pathway genes and a pro-angiogenic phenotype in CLL cells

(2008) J. Edelmann et al.   LEUKEMIA RESEARCH

Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians

(2008) Guillaume Smits et al.   NATURE GENETICS

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

(2008) Désirée Bonci et al.   NATURE MEDICINE

Monoclonal B-Cell Lymphocytosis and Chronic Lymphocytic Leukemia

(2008) Andy C. Rawstron et al.   NEW ENGLAND JOURNAL OF MEDICINE

miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes

(2008) Q. Liu et al.   NUCLEIC ACIDS RESEARCH

The Antisense Transcriptomes of Human Cells

(2008) Yiping He et al.   SCIENCE