Modeling Dynamics of Cell-to-Cell Variability in TRAIL-Induced Apoptosis Explains Fractional Killing and Predicts Reversible Resistance
出版年份 2014 全文链接
标题
Modeling Dynamics of Cell-to-Cell Variability in TRAIL-Induced Apoptosis Explains Fractional Killing and Predicts Reversible Resistance
作者
关键词
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出版物
PLoS Computational Biology
Volume 10, Issue 10, Pages e1003893
出版商
Public Library of Science (PLoS)
发表日期
2014-10-24
DOI
10.1371/journal.pcbi.1003893
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A Computational Framework for Analyzing Stochasticity in Gene Expression
- (2014) Marc S. Sherman et al. PLoS Computational Biology
- Quantifying the contribution of chromatin dynamics to stochastic gene expression reveals long, locus-dependent periods between transcriptional bursts
- (2013) José Viñuelas et al. BMC BIOLOGY
- Systems Analysis of BCL2 Protein Family Interactions Establishes a Model to Predict Responses to Chemotherapy
- (2013) A. U. Lindner et al. CANCER RESEARCH
- Selective CDK9 inhibition overcomes TRAIL resistance by concomitant suppression of cFlip and Mcl-1
- (2013) J Lemke et al. CELL DEATH AND DIFFERENTIATION
- Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes
- (2013) Deborah A. Flusberg et al. MOLECULAR BIOLOGY OF THE CELL
- Modulating cell-to-cell variability and sensitivity to death ligands by co-drugging
- (2013) Deborah A Flusberg et al. PHYSICAL BIOLOGY
- Stimulus-induced modulation of transcriptional bursting in a single mammalian gene
- (2013) N. Molina et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systematic Identification of Signal-Activated Stochastic Gene Regulation
- (2013) G. Neuert et al. SCIENCE
- STL-based Analysis of TRAIL-induced Apoptosis Challenges the Notion of Type I/Type II Cell Line Classification
- (2013) Szymon Stoma et al. PLoS Computational Biology
- Proteasome Inhibition Can Impair Caspase-8 Activation upon Submaximal Stimulation of Apoptotic Tumor Necrosis Factor-related Apoptosis Inducing Ligand (TRAIL) Signaling
- (2012) Maike A. Laussmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death
- (2012) Laura S. Dickens et al. MOLECULAR CELL
- Stoichiometry of the CD95 Death-Inducing Signaling Complex: Experimental and Modeling Evidence for a Death Effector Domain Chain Model
- (2012) Kolja Schleich et al. MOLECULAR CELL
- Dynamics of protein noise can distinguish between alternate sources of gene-expression variability
- (2012) Abhyudai Singh et al. Molecular Systems Biology
- On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics
- (2012) L Y Dimberg et al. ONCOGENE
- Transcriptional burst frequency and burst size are equally modulated across the human genome
- (2012) R. D. Dar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exploring the Contextual Sensitivity of Factors that Determine Cell-to-Cell Variability in Receptor-Mediated Apoptosis
- (2012) Suzanne Gaudet et al. PLoS Computational Biology
- Heterogeneity reduces sensitivity of cell death for TNF-Stimuli
- (2011) Monica Schliemann et al. BMC Systems Biology
- Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
- (2011) Piyush B. Gupta et al. CELL
- Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis
- (2011) B. B. Aldridge et al. Molecular Systems Biology
- TRAIL-R4 Promotes Tumor Growth and Resistance to Apoptosis in Cervical Carcinoma HeLa Cells through AKT
- (2011) Najoua Lalaoui et al. PLoS One
- Mammalian Genes Are Transcribed with Widely Different Bursting Kinetics
- (2011) D. M. Suter et al. SCIENCE
- Targeting c-FLIP in cancer
- (2010) Sarah Shirley et al. CANCER LETTERS
- TRAIL-activated stress kinases suppress apoptosis through transcriptional upregulation of MCL-1
- (2010) J K Son et al. CELL DEATH AND DIFFERENTIATION
- Dynamics within the CD95 death-inducing signaling complex decide life and death of cells
- (2010) Leo Neumann et al. Molecular Systems Biology
- Single-cell NF-κB dynamics reveal digital activation and analogue information processing
- (2010) Savaş Tay et al. NATURE
- Dynamics of outer mitochondrial membrane permeabilization during apoptosis
- (2009) M Rehm et al. CELL DEATH AND DIFFERENTIATION
- Listening to the noise: random fluctuations reveal gene network parameters
- (2009) Brian Munsky et al. Molecular Systems Biology
- Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
- (2009) Sabrina L. Spencer et al. NATURE
- Intrinsic noise, dissipation cost, and robustness of cellular networks: The underlying energy landscape of MAPK signal transduction
- (2008) S. Lapidus et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modeling a Snap-Action, Variable-Delay Switch Controlling Extrinsic Cell Death
- (2008) John G Albeck et al. PLOS BIOLOGY
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