Coarse-Grained Molecular Simulation of Epidermal Growth Factor Receptor Protein Tyrosine Kinase Multi-Site Self-Phosphorylation

Architecture and Membrane Interactions of the EGF Receptor

(2013) Anton Arkhipov et al.   CELL

EGFR: Tale of the C-terminal tail

(2013) Ketan S. Gajiwala   PROTEIN SCIENCE

Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization

(2012) Yibing Shan et al.   CELL

Computational study of EGFR inhibition: molecular dynamics studies on the active and inactive protein conformations

(2012) Napat Songtawee et al.   JOURNAL OF MOLECULAR MODELING

HER2 stabilizes EGFR and itself by altering autophosphorylation patterns in a manner that overcomes regulatory mechanisms and promotes proliferative and transformation signaling

(2012) Z Hartman et al.   ONCOGENE

Pari passu dimers of dimers

(2012) M. X. Sliwkowski   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling

(2012) Q. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mass Spectrometry Mapping of Epidermal Growth Factor Receptor Phosphorylation Related to Oncogenic Mutations and Tyrosine Kinase Inhibitor Sensitivity

(2010) Guolin Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Structural Evidence for Loose Linkage between Ligand Binding and Kinase Activation in the Epidermal Growth Factor Receptor

(2010) C. Lu et al.   MOLECULAR AND CELLULAR BIOLOGY

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

(2010) Fumin Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational regulation of the EGFR kinase core by the juxtamembrane and C-terminal tail: A molecular dynamics study

(2010) Morad Mustafa et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Mechanism for Activation of the EGF Receptor Catalytic Domain by the Juxtamembrane Segment

(2009) Natalia Jura et al.   CELL

Coarse grained simulations of a small peptide: Effects of finite damping and hydrodynamic interactions

(2009) Uwe Winter et al.   JOURNAL OF CHEMICAL PHYSICS

Striking Effects of Hydrodynamic Interactions on the Simulated Diffusion and Folding of Proteins

(2009) Tamara Frembgen-Kesner et al.   Journal of Chemical Theory and Computation

The Juxtamembrane Region of the EGF Receptor Functions as an Activation Domain

(2009) Monica Red Brewer et al.   MOLECULAR CELL

Hierarchical Modeling of Activation Mechanisms in the ABL and EGFR Kinase Domains: Thermodynamic and Mechanistic Catalysts of Kinase Activation by Cancer Mutations

(2009) Anshuman Dixit et al.   PLoS Computational Biology

Structure-Based View of Epidermal Growth Factor Receptor Regulation

(2008) Kathryn M. Ferguson   Annual Review of Biophysics

ERBB3/HER3 and ERBB2/HER2 Duet in Mammary Development and Breast Cancer

(2008) David F. Stern   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2

(2008) Jinhua Wu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A crystallographic snapshot of tyrosine trans-phosphorylation in action

(2008) H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational dynamics of the EGFR kinase domain reveals structural features involved in activation

(2008) Athanasios Papakyriakou et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS