Conformational regulation of the EGFR kinase core by the juxtamembrane and C-terminal tail: A molecular dynamics study

Mig-6 controls EGFR trafficking and suppresses gliomagenesis

(2010) H. Ying et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Principal component analysis of native ensembles of biomolecular structures (PCA_NEST): insights into functional dynamics

(2009) Lee-Wei Yang et al.   BIOINFORMATICS

Atomistic Insights into Regulatory Mechanisms of the HER2 Tyrosine Kinase Domain: A Molecular Dynamics Study

(2009) Shannon E. Telesco et al.   BIOPHYSICAL JOURNAL

Mechanism for Activation of the EGF Receptor Catalytic Domain by the Juxtamembrane Segment

(2009) Natalia Jura et al.   CELL

Principal component analysis on molecular descriptors as an alternative point of view in the search of new Hsp90 inhibitors

(2009) Antonino Lauria et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

The Juxtamembrane Region of the EGF Receptor Functions as an Activation Domain

(2009) Monica Red Brewer et al.   MOLECULAR CELL

Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3

(2009) N. Jura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oncogenic EGFR Signaling Networks in Glioma

(2009) P. H. Huang et al.   Science Signaling

Hierarchical Modeling of Activation Mechanisms in the ABL and EGFR Kinase Domains: Thermodynamic and Mechanistic Catalysts of Kinase Activation by Cancer Mutations

(2009) Anshuman Dixit et al.   PLoS Computational Biology

Structure and Clinical Relevance of the Epidermal Growth Factor Receptor in Human Cancer

(2008) Amit Kumar et al.   JOURNAL OF CLINICAL ONCOLOGY

6-Ethynylthieno[3,2-d]- and 6-ethynylthieno[2,3-d]pyrimidin-4-anilines as tunable covalent modifiers of ErbB kinases

(2008) E. R. Wood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

(2008) C.-H. Yun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detailed conformational dynamics of juxtamembrane region and activation loop in c-Kit kinase activation process

(2008) Jun Zou et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Conformational dynamics of the EGFR kinase domain reveals structural features involved in activation

(2008) Athanasios Papakyriakou et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS