A systems genetics resource and analysis of sleep regulation in the mouse

Perilipins: a diversity of intracellular lipid droplet proteins

(2017) Hiroyuki Itabe et al.   Lipids in Health and Disease

Hypocretin (orexin) is critical in sustaining theta/gamma-rich waking behaviors that drive sleep need

(2017) Anne Vassalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abnormalities in the Polysomnographic, Adenosine and Metabolic Response to Sleep Deprivation in an Animal Model of Hyperammonemia

(2017) Selena Marini et al.   Frontiers in Physiology

The State of Systems Genetics in 2017

(2017) Nitin S. Baliga et al.   Cell Systems

Separating the Contribution of Glucocorticoids and Wakefulness to the Molecular and Electrophysiological Correlates of Sleep Homeostasis

(2017) Valérie Mongrain et al.   SLEEP

Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity

(2016) Carsten Merkwirth et al.   CELL

Forward-genetics analysis of sleep in randomly mutagenized mice

(2016) Hiromasa Funato et al.   NATURE

Genetics of cardiovascular diseases: lessons learned from a decade of genomics research in Iceland

(2016) David O. Arnar et al.   SCANDINAVIAN CARDIOVASCULAR JOURNAL

Causal evidence for the role of REM sleep theta rhythm in contextual memory consolidation

(2016) R. Boyce et al.   SCIENCE

Systems proteomics of liver mitochondria function

(2016) E. G. Williams et al.   SCIENCE

A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion

(2016) Alexandre Picard et al.   Cell Reports

Prevalence of Healthy Sleep Duration among Adults — United States, 2014

(2016) Yong Liu et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

The FAIR Guiding Principles for scientific data management and stewardship

(2016) Mark D. Wilkinson et al.   Scientific Data

Genome-wide detection of intervals of genetic heterogeneity associated with complex traits

(2015) Felipe Llinares-López et al.   BIOINFORMATICS

Fast and efficient QTL mapper for thousands of molecular phenotypes

(2015) Halit Ongen et al.   BIOINFORMATICS

Sleep restriction increases free fatty acids in healthy men

(2015) Josiane L. Broussard et al.   DIABETOLOGIA

An epidemiological perspective of personalized medicine: the Estonian experience

(2015) L. Milani et al.   JOURNAL OF INTERNAL MEDICINE

Characterizing KIF16B in Neurons Reveals a Novel Intramolecular "Stalk Inhibition" Mechanism That Regulates Its Capacity to Potentiate the Selective Somatodendritic Localization of Early Endosomes

(2015) A. Farkhondeh et al.   JOURNAL OF NEUROSCIENCE

WRN translocation from nucleolus to nucleoplasm is regulated by SIRT1 and required for DNA repair and the development of chemoresistance

(2015) Sun-Young Lee et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Deciphering the spatio-temporal expression and stress regulation of Fam107B, the paralog of the resilience-promoting protein DRR1 in the mouse brain

(2015) M. Masana et al.   NEUROSCIENCE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Sleep Deprivation and Oxidative Stress in Animal Models: A Systematic Review

(2015) Gabriel Villafuerte et al.   Oxidative Medicine and Cellular Longevity

A Systems Approach Identifies Networks and Genes Linking Sleep and Stress: Implications for Neuropsychiatric Disorders

(2015) Peng Jiang et al.   Cell Reports

The metabolic burden of sleep loss

(2015) Sebastian M Schmid et al.   Lancet Diabetes & Endocrinology

Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice

(2015) Lucie Aumailley et al.   PLoS One

Catabolism of Branched Chain Amino Acids Contributes Significantly to Synthesis of Odd-Chain and Even-Chain Fatty Acids in 3T3-L1 Adipocytes

(2015) Scott B. Crown et al.   PLoS One

Diurnal rhythms in the human urine metabolome during sleep and total sleep deprivation

(2015) Guro F. Giskeødegård et al.   Scientific Reports

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Multilayered Genetic and Omics Dissection of Mitochondrial Activity in a Mouse Reference Population

(2014) Yibo Wu et al.   CELL

Tubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon

(2014) C. Rocha et al.   EMBO JOURNAL

Polyunsaturated fatty acids and their metabolites in brain function and disease

(2014) Richard P. Bazinet et al.   NATURE REVIEWS NEUROSCIENCE

Sleep and the Price of Plasticity: From Synaptic and Cellular Homeostasis to Memory Consolidation and Integration

(2014) Giulio Tononi et al.   NEURON

Effect of sleep deprivation on the human metabolome

(2014) S. K. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Injury and Repair Resulting from Sleep Loss and Sleep Recovery in Laboratory Rats

(2014) Carol A. Everson et al.   SLEEP

Downregulation of the Werner syndrome protein induces a metabolic shift that compromises redox homeostasis and limits proliferation of cancer cells

(2013) Baomin Li et al.   AGING CELL

NAD+metabolism: A therapeutic target for age-related metabolic disease

(2013) Laurent Mouchiroud et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Systems genetics approaches to understand complex traits

(2013) Mete Civelek et al.   NATURE REVIEWS GENETICS

Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Systems Genetics of Metabolism: The Use of the BXD Murine Reference Panel for Multiscalar Integration of Traits

(2012) Pénélope A. Andreux et al.   CELL

Interplay between Lipids and Branched-Chain Amino Acids in Development of Insulin Resistance

(2012) Christopher B. Newgard   Cell Metabolism

Computational tools for prioritizing candidate genes: boosting disease gene discovery

(2012) Yves Moreau et al.   NATURE REVIEWS GENETICS

Effects of Partial and Acute Total Sleep Deprivation on Performance across Cognitive Domains, Individuals and Circadian Phase

(2012) June C. Lo et al.   PLoS One

Targeted deletion of thioesterase superfamily member 1 promotes energy expenditure and protects against obesity and insulin resistance

(2012) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New players on the metabolic stage

(2012) David E. Cohen   Adipocyte

Hive plots--rational approach to visualizing networks

(2011) M. Krzywinski et al.   BRIEFINGS IN BIOINFORMATICS

KIF16B/Rab14 Molecular Motor Complex Is Critical for Early Embryonic Development by Transporting FGF Receptor

(2011) Hitoshi Ueno et al.   DEVELOPMENTAL CELL

Removal of Synaptic Ca2+-Permeable AMPA Receptors during Sleep

(2011) F. Lante et al.   JOURNAL OF NEUROSCIENCE

Acute sleep deprivation: the effects of the AMPAKINE compound CX717 on human cognitive performance, alertness and recovery sleep

(2011) Julia Boyle et al.   JOURNAL OF PSYCHOPHARMACOLOGY

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition

(2011) M. V. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arc in synaptic plasticity: from gene to behavior

(2011) Erica Korb et al.   TRENDS IN NEUROSCIENCES

FastEpistasis: a high performance computing solution for quantitative trait epistasis

(2010) Thierry Schüpbach et al.   BIOINFORMATICS

Sleep Restriction for 1 Week Reduces Insulin Sensitivity in Healthy Men

(2010) O. M. Buxton et al.   DIABETES

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

12-Lipoxygenase Regulates Hippocampal Long-Term Potentiation by Modulating L-Type Ca2+ Channels

(2010) A. J. DeCostanzo et al.   JOURNAL OF NEUROSCIENCE

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Age-related changes in sleep in inbred mice are genotype dependent

(2010) Sibah Hasan et al.   NEUROBIOLOGY OF AGING

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Computational analysis of gene regulation in animal sleep deprivation

(2010) Haifang Wang et al.   PHYSIOLOGICAL GENOMICS

Slow-wave sleep deficiency and enhancement: Implications for insomnia and its management

(2010) Derk-Jan Dijk   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Disentangling molecular relationships with a causal inference test

(2009) Joshua Millstein et al.   BMC GENETICS

Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep

(2009) Susan T Harbison et al.   NATURE GENETICS

Genetics of Sleep

(2008) Rozi Andretic et al.   Annual Review of Genetics

Practical Applications of the Bioinformatics Toolbox for Narrowing Quantitative Trait Loci

(2008) S. L. Burgess-Herbert et al.   GENETICS

The clinical characteristics of Werner syndrome: molecular and biochemical diagnosis

(2008) Meltem Muftuoglu et al.   HUMAN GENETICS

Molecular and electrophysiological evidence for net synaptic potentiation in wake and depression in sleep

(2008) Vladyslav V Vyazovskiy et al.   NATURE NEUROSCIENCE

Sleep as a fundamental property of neuronal assemblies

(2008) James M. Krueger et al.   NATURE REVIEWS NEUROSCIENCE

Identification of SLEEPLESS, a Sleep-Promoting Factor

(2008) K. Koh et al.   SCIENCE