Live Cell Imaging Unveils Multiple Domain Requirements for In Vivo Dimerization of the Glucocorticoid Receptor

New Insights into the Anti-inflammatory Mechanisms of Glucocorticoids: An Emerging Role for Glucocorticoid-Receptor-Mediated Transactivation

(2013) Sofie Vandevyver et al.   ENDOCRINOLOGY

Single-molecule imaging of transcription factor binding to DNA in live mammalian cells

(2013) J Christof M Gebhardt et al.   NATURE METHODS

The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals

(2013) Lisa C Watson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Impact of Glucocorticoid Receptor Density on Ligand-Independent Dimerization, Cooperative Ligand-Binding and Basal Priming of Transactivation: A Cell Culture Model

(2013) Steven Robertson et al.   PLoS One

Glucocorticoid Receptor–Promoter Interactions: Energetic Dissection Suggests a Framework for the Specificity of Steroid Receptor-Mediated Gene Regulation

(2012) James P. Robblee et al.   BIOCHEMISTRY

Sequence and chromatin determinants of cell-type-specific transcription factor binding

(2012) A. Arvey et al.   GENOME RESEARCH

NF-κB regulation: lessons from structures

(2012) Gourisankar Ghosh et al.   IMMUNOLOGICAL REVIEWS

Thymocyte responsiveness to endogenous glucocorticoids is required for immunological fitness

(2012) Paul R. Mittelstadt et al.   JOURNAL OF CLINICAL INVESTIGATION

The structural basis of direct glucocorticoid-mediated transrepression

(2012) William H Hudson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

It takes two to tango: Dimerisation of glucocorticoid receptor and its anti-inflammatory functions

(2012) Mark Nixon et al.   STEROIDS

Widespread Negative Response Elements Mediate Direct Repression by Agonist- Liganded Glucocorticoid Receptor

(2011) Milan Surjit et al.   CELL

Dynamic Exchange at Regulatory Elements during Chromatin Remodeling Underlies Assisted Loading Mechanism

(2011) Ty C. Voss et al.   CELL

Number and brightness image analysis reveals ATF-induced dimerization kinetics of uPAR in the cell membrane

(2011) Christian Hellriegel et al.   FASEB JOURNAL

Complex Human Glucocorticoid Receptor dim Mutations Define Glucocorticoid Induced Apoptotic Resistance in Bone Cells

(2011) Christine M. Jewell et al.   MOLECULAR ENDOCRINOLOGY

Chromatin accessibility pre-determines glucocorticoid receptor binding patterns

(2011) Sam John et al.   NATURE GENETICS

Maps and legends: The quest for dissociated ligands of the glucocorticoid receptor

(2011) Andrew R. Clark et al.   PHARMACOLOGY & THERAPEUTICS

Glucocorticoid receptor mutants: man-made tools for functional research

(2011) Ilse M. Beck et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor

(2010) Raoul Frijters et al.   BMC GENOMICS

Structure of the Glucocorticoid Receptor, a Flexible Protein That Can Adapt to Different Ligands

(2010) Adriana S. Veleiro et al.   ChemMedChem

Insights on Glucocorticoid Receptor Activity Modulation through the Binding of Rigid Steroids

(2010) Diego M. Presman et al.   PLoS One

Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis

(2010) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetic Complexity of the Global Response to Glucocorticoid Receptor Action

(2009) Sam John et al.   ENDOCRINOLOGY

Abrogation of Glucocorticoid Receptor Dimerization Correlates with Dissociated Glucocorticoid Behavior of Compound A

(2009) Steven Robertson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcription Dynamics

(2009) Gordon L. Hager et al.   MOLECULAR CELL

Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription

(2009) Diana A. Stavreva et al.   NATURE CELL BIOLOGY

Sustained Oscillations of NF-κB Produce Distinct Genome Scanning and Gene Expression Profiles

(2009) Myong-Hee Sung et al.   PLoS One

Stoichiometry of molecular complexes at adhesions in living cells

(2009) M. A. Digman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

(2009) S. H. Meijsing et al.   SCIENCE

Exploring the Molecular Basis of Action of the Passive Antiglucocorticoid 21-Hydroxy-6,19-epoxyprogesterone

(2008) Lautaro D. Álvarez et al.   JOURNAL OF MEDICINAL CHEMISTRY

Minireview: Latest Perspectives on Antiinflammatory Actions of Glucocorticoids

(2008) Karolien De Bosscher et al.   MOLECULAR ENDOCRINOLOGY

Mapping the Number of Molecules and Brightness in the Laser Scanning Microscope

(2007) Michelle A. Digman et al.   BIOPHYSICAL JOURNAL