Hedgehog-Regulated Ubiquitination Controls Smoothened Trafficking and Cell Surface Expression in Drosophila

Mechanisms and functions of Hedgehog signalling across the metazoa

(2011) Philip W. Ingham et al.   NATURE REVIEWS GENETICS

Sonic Hedgehog Dependent Phosphorylation by CK1α and GRK2 Is Required for Ciliary Accumulation and Activation of Smoothened

(2011) Yongbin Chen et al.   PLOS BIOLOGY

Role of the Drosophila Non-Visual ß-Arrestin Kurtz in Hedgehog Signalling

(2011) Cristina Molnar et al.   PLoS Genetics

Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt

(2010) Akiko Mukai et al.   EMBO JOURNAL

G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in Drosophila

(2010) Y. Chen et al.   GENES & DEVELOPMENT

Ligand-induced EpoR internalization is mediated by JAK2 and p85 and is impaired by mutations responsible for primary familial and congenital polycythemia

(2009) R. Sulahian et al.   BLOOD

Regulation of Smoothened by Drosophila G-protein-coupled receptor kinases

(2009) Shuofei Cheng et al.   DEVELOPMENTAL BIOLOGY

Hedgehog Signaling in Development and Cancer

(2008) Jin Jiang et al.   DEVELOPMENTAL CELL

Nedd4 Mediates Agonist-dependent Ubiquitination, Lysosomal Targeting, and Degradation of the β2-Adrenergic Receptor

(2008) Sudha K. Shenoy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 -Arrestin-Mediated Localization of Smoothened to the Primary Cilium

(2008) J. J. Kovacs et al.   SCIENCE