Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin

Repression of Antibiotic Downregulator WblA by AdpA in Streptomyces coelicolor

(2013) Han-Na Lee et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Exogenous 1,4-butyrolactone stimulates A-factor-like cascade and validamycin biosynthesis inStreptomyces hygroscopicus5008

(2013) Gao-Yi Tan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Molecular Regulation of Antibiotic Biosynthesis in Streptomyces

(2013) G. Liu et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

ABC transporter genes from Streptomyces ghanaensis moenomycin biosynthetic gene cluster: roles in antibiotic production and export

(2012) Bohdan Ostash et al.   ARCHIVES OF MICROBIOLOGY

Genome-wide Distribution of AdpA, a Global Regulator for Secondary Metabolism and Morphological Differentiation in Streptomyces, Revealed the Extent and Complexity of the AdpA Regulatory Network

(2012) A. Higo et al.   DNA RESEARCH

AdpA, key regulator for morphological differentiation regulates bacterial chromosome replication

(2012) M. Wolanski et al.   Open Biology

β-Glucuronidase as a Sensitive and Versatile Reporter in Actinomycetes

(2011) Maksym Myronovskyi et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

FIMO: scanning for occurrences of a given motif

(2011) Charles E. Grant et al.   BIOINFORMATICS

The Level of AdpA Directly Affects Expression of Developmental Genes in Streptomyces coelicolor

(2011) Marcin Wolański et al.   JOURNAL OF BACTERIOLOGY

Biosynthesis and Regulation of Grisemycin, a New Member of the Linaridin Family of Ribosomally Synthesized Peptides Produced by Streptomyces griseus IFO 13350

(2011) J. Claesen et al.   JOURNAL OF BACTERIOLOGY

Strain improvement in actinomycetes in the postgenomic era

(2011) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis

(2011) Y.-L. Du et al.   MICROBIOLOGY-SGM

tRNA accumulation and suppression of the bldA phenotype during development in Streptomyces coelicolor

(2011) B. M. Fredrik Pettersson et al.   MOLECULAR MICROBIOLOGY

Strict regulation of morphological differentiation and secondary metabolism by a positive feedback loop between two global regulators AdpA and BldA in Streptomyces griseus

(2011) Akiyoshi Higo et al.   MOLECULAR MICROBIOLOGY

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances

(2011) Gilles P. van Wezel et al.   NATURAL PRODUCT REPORTS

Pacidamycin Biosynthesis: Identification and Heterologous Expression of the First Uridyl Peptide Antibiotic Gene Cluster

(2010) Emma J. Rackham et al.   CHEMBIOCHEM

The Sequence of a 1.8-Mb Bacterial Linear Plasmid Reveals a Rich Evolutionary Reservoir of Secondary Metabolic Pathways

(2010) Marnix H. Medema et al.   Genome Biology and Evolution

Genetic factors that influence moenomycin production in streptomycetes

(2010) Roman Makitrynskyy et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Morphological differentiation and clavulanic acid formation are affected in a Streptomyces clavuligerus adpA-deleted mutant

(2010) M. T. Lopez-Garcia et al.   MICROBIOLOGY-SGM

Regulation of morphological differentiation inS. coelicolorby RNase III (AbsB) cleavage of mRNA encoding the AdpA transcription factor

(2010) Weijing Xu et al.   MOLECULAR MICROBIOLOGY

Genes essential for morphological development and antibiotic production in Streptomyces coelicolor are targets of BldD during vegetative growth

(2010) Chris D. Den Hengst et al.   MOLECULAR MICROBIOLOGY

Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity

(2010) Bohdan Ostash et al.   NATURAL PRODUCT REPORTS

Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics

(2010) W. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissecting tunicamycin biosynthesis by genome mining: cloning and heterologous expression of a minimal gene cluster

(2010) Filip J. Wyszynski et al.   Chemical Science

Genome-wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus

(2010) Marnix H. Medema et al.   Microbial Biotechnology

Complete Characterization of the Seventeen Step Moenomycin Biosynthetic Pathway

(2009) Bohdan Ostash et al.   BIOCHEMISTRY

TTA Lynx: a web-based service for analysis of actinomycete genes containing rare TTA codon

(2009) Nestor Zaburannyy et al.   BIOINFORMATICS

Thiostrepton Biosynthesis: Prototype for a New Family of Bacteriocins

(2009) Wendy L. Kelly et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA microarray analysis of global gene regulation by A-factor in Streptomyces griseus

(2009) H. Hara et al.   MICROBIOLOGY-SGM

The pleiotropic regulator AdpA-L directly controls the pathway-specific activator of nikkomycin biosynthesis inStreptomyces ansochromogenes

(2009) Yuanyuan Pan et al.   MOLECULAR MICROBIOLOGY

Dynamic changes in the extracellular proteome caused by absence of a pleiotropic regulator AdpA inStreptomyces griseus

(2009) Genki Akanuma et al.   MOLECULAR MICROBIOLOGY

Recent advances in thiopeptideantibiotic biosynthesis

(2009) Chaoxuan Li et al.   NATURAL PRODUCT REPORTS

Identification and characterization of Streptomyces ghanaensis ATCC14672 integration sites for three actinophage-based plasmids

(2009) Bohdan Ostash et al.   PLASMID

Evolutionary flux of potentially bldA-dependent Streptomyces genes containing the rare leucine codon TTA

(2008) Govind Chandra et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Growth-Regulated Expression of a Bacteriocin, Produced by the Sweet Potato Pathogen Streptomyces ipomoeae, That Exhibits Interstrain Inhibition

(2008) J. Wang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Gene Encoding RNase III in Streptomyces coelicolor Is Transcribed during Exponential Phase and Is Required for Antibiotic Production and for Proper Sporulation

(2008) J. K. Sello et al.   JOURNAL OF BACTERIOLOGY

The use of the rare UUA codon to define “Expression Space” for genes involved in secondary metabolism, development and environmental adaptation in Streptomyces

(2008) Keith F. Chater et al.   JOURNAL OF MICROBIOLOGY

Identification of transcriptional activators for thienamycin and cephamycin C biosynthetic genes within the thienamycin gene cluster fromStreptomyces cattleya

(2008) Miriam Rodríguez et al.   MOLECULAR MICROBIOLOGY