Physiological and pathophysiological functions of cell cycle proteins in post-mitotic neurons: implications for Alzheimer’s disease

Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease

(2016) David J. Bonda et al.   Aging-US

Quantification of the Brain Proteome in Alzheimer’s Disease Using Multiplexed Mass Spectrometry

(2014) Sravani Musunuri et al.   JOURNAL OF PROTEOME RESEARCH

The Interaction of the Atm Genotype with Inflammation and Oxidative Stress

(2014) Yan Yang et al.   PLoS One

Repair of Oxidative DNA Damage, Cell-Cycle Regulation and Neuronal Death May Influence the Clinical Manifestation of Alzheimer’s Disease

(2014) Aderbal R. T. Silva et al.   PLoS One

2013 Alzheimer's disease facts and figures

(2013)   Alzheimers & Dementia

Protein kinase C activation causes neurite retraction via cyclinD1 and p60-katanin increase in rat hippocampal neurons

(2013) Sirin Korulu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Amyloid-  signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease

(2013) M. E. Seward et al.   JOURNAL OF CELL SCIENCE

Regulation of the DNA Damage Response by Cyclin-Dependent Kinases

(2013) Camilla Trovesi et al.   JOURNAL OF MOLECULAR BIOLOGY

Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β

(2013) Elsa Suberbielle et al.   NATURE NEUROSCIENCE

Specific Glial Functions Contribute to Schizophrenia Susceptibility

(2013) A. Goudriaan et al.   SCHIZOPHRENIA BULLETIN

Controlling DNA-end resection: a new task for CDKs

(2013) Lorenza P. Ferretti et al.   Frontiers in Genetics

ERK activation and expression of neuronal cell cycle markers in the hippocampus after entorhinal cortex lesion

(2012) Karina Hernández-Ortega et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Label-Free Quantitative LC–MS Proteomics of Alzheimer’s Disease and Normally Aged Human Brains

(2012) Victor P. Andreev et al.   JOURNAL OF PROTEOME RESEARCH

The DNA Replication Stress Hypothesis of Alzheimer’s Disease

(2012) Yuri B. Yurov et al.   TheScientificWorldJOURNAL

Effect of ionizing radiation in sensory ganglion neurons: organization and dynamics of nuclear compartments of DNA damage/repair and their relationship with transcription and cell cycle

(2011) Iñigo Casafont et al.   ACTA NEUROPATHOLOGICA

A neuroprotective role for the DNA damage checkpoint in tauopathy

(2011) Vikram Khurana et al.   AGING CELL

Cyclin E Constrains Cdk5 Activity to Regulate Synaptic Plasticity and Memory Formation

(2011) Junko Odajima et al.   DEVELOPMENTAL CELL

Sublethal Doses of β-Amyloid Peptide Abrogate DNA-dependent Protein Kinase Activity

(2011) Alessio Cardinale et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stable Brain ATM Message and Residual Kinase-Active ATM Protein in Ataxia-Telangiectasia

(2011) J. Li et al.   JOURNAL OF NEUROSCIENCE

Cross-talk between cell cycle induction and mitochondrial dysfunction during oxidative stress and nerve growth factor withdrawal in differentiated PC12 cells

(2011) Maria Rosaria Bianco et al.   JOURNAL OF NEUROSCIENCE RESEARCH

DNA damage and cell cycle events implicate cerebellar dentate nucleus neurons as targets of Alzheimer's disease

(2011) Jianmin Chen et al.   Molecular Neurodegeneration

Cdk5: a multifaceted kinase in neurodegenerative diseases

(2011) Zelda H. Cheung et al.   TRENDS IN CELL BIOLOGY

Selective Cell Death of Hyperploid Neurons in Alzheimer’s Disease

(2010) Thomas Arendt et al.   AMERICAN JOURNAL OF PATHOLOGY

Cyclin-C-dependent cell-cycle entry is required for activation of non-homologous end joining DNA repair in postmitotic neurons

(2010) A Tomashevski et al.   CELL DEATH AND DIFFERENTIATION

Cdk5 Suppresses the Neuronal Cell Cycle by Disrupting the E2F1-DP1 Complex

(2010) J. Zhang et al.   JOURNAL OF NEUROSCIENCE

APCCdh1 mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity

(2010) Amy K Y Fu et al.   NATURE NEUROSCIENCE

The Neuronal Expression of MYC Causes a Neurodegenerative Phenotype in a Novel Transgenic Mouse

(2009) Hyoung-gon Lee et al.   AMERICAN JOURNAL OF PATHOLOGY

A Centrosomal Cdc20-APC Pathway Controls Dendrite Morphogenesis in Postmitotic Neurons

(2009) Albert H. Kim et al.   CELL

A putative role for cell cycle-related proteins in microtubule-based neuroplasticity

(2009) Stefanie Schmetsdorf et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The PI3K-Akt-mTOR pathway regulates Aβ oligomer induced neuronal cell cycle events

(2009) Kiran Bhaskar et al.   Molecular Neurodegeneration

An essential role of the aPKC–Aurora A–NDEL1 pathway in neurite elongation by modulation of microtubule dynamics

(2009) Daisuke Mori et al.   NATURE CELL BIOLOGY

Aneuploidy in the normal, Alzheimer's disease and ataxia-telangiectasia brain: Differential expression and pathological meaning

(2009) Ivan Y. Iourov et al.   NEUROBIOLOGY OF DISEASE

A Reevaluation of Tetraploidy in the Alzheimer’s Disease Brain

(2009) Jurjen W. Westra et al.   Neurodegenerative Diseases

Alternative Functions of Core Cell Cycle Regulators in Neuronal Migration, Neuronal Maturation, and Synaptic Plasticity

(2009) Christopher L. Frank et al.   NEURON

AAV-Tau Mediates Pyramidal Neurodegeneration by Cell-Cycle Re-Entry without Neurofibrillary Tangle Formation in Wild-Type Mice

(2009) Tomasz Jaworski et al.   PLoS One

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

Different fibrillar Aβ 1–42 concentrations induce adult hippocampal neurons to reenter various phases of the cell cycle

(2008) Shohreh Majd et al.   BRAIN RESEARCH

Mutations in String/CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of Ataxia telangiectasia

(2008) S. A. Rimkus et al.   GENES & DEVELOPMENT

A  Oligomers Induce Neuronal Cell Cycle Events in Alzheimer's Disease

(2008) N. H. Varvel et al.   JOURNAL OF NEUROSCIENCE

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

Critical Role of CDK5 and Polo-like Kinase 2 in Homeostatic Synaptic Plasticity during Elevated Activity

(2008) Daniel P. Seeburg et al.   NEURON

Activation of FOXO1 by Cdk1 in Cycling Cells and Postmitotic Neurons

(2008) Z. Yuan et al.   SCIENCE