Endothelin Receptors Expressed by Immune Cells Are Involved in Modulation of Inflammation and in Fibrosis: Relevance to the Pathogenesis of Systemic Sclerosis

The Role of Endothelin-1 and Endothelin Receptor Antagonists in Inflammatory Response and Sepsis

(2014) Agata Kowalczyk et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Endothelin and endothelin antagonists in chronic kidney disease

(2014) Donald E Kohan et al.   KIDNEY INTERNATIONAL

The Endothelin A Receptor Mediates Fibrocyte Differentiation in Chronic Obstructive Asthma. The Involvement of Connective Tissue Growth Factor

(2013) Chih-Ming Weng et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Treatment of Idiopathic Pulmonary Fibrosis With Ambrisentan

(2013) Ganesh Raghu   ANNALS OF INTERNAL MEDICINE

2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative

(2013) Frank van den Hoogen et al.   ANNALS OF THE RHEUMATIC DISEASES

2013 Classification Criteria for Systemic Sclerosis: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative

(2013) Frank van den Hoogen et al.   ARTHRITIS AND RHEUMATISM

The Effect of the Endothelin-1 Receptor Antagonist, Bosentan, on Patients with Poorly Controlled Asthma: A 17-week, Double-Blind, Placebo-Controlled Crossover Pilot Study

(2013) Timothy B. Coyle et al.   JOURNAL OF ASTHMA

C-terminus of ETA/ETBreceptors regulate endothelin-1 signal transmission

(2013) Achani Yatawara et al.   JOURNAL OF PEPTIDE SCIENCE

Differential expression of junctional adhesion molecules in different stages of systemic sclerosis

(2012) Mirko Manetti et al.   ARTHRITIS AND RHEUMATISM

Scleroderma – New aspects in pathogenesis and treatment

(2012) Alexandra Balbir-Gurman et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Pro-fibrotic processes in human lung fibroblasts are driven by an autocrine/paracrine endothelinergic system

(2012) AS Ahmedat et al.   BRITISH JOURNAL OF PHARMACOLOGY

Clinical trials with endothelin receptor antagonists: What went wrong and where can we improve?

(2012) Donald E. Kohan et al.   LIFE SCIENCES

Endothelin-1, the Unfolded Protein Response, and Persistent Inflammation

(2011) Michael E. Yeager et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Bosentan treatment of digital ulcers related to systemic sclerosis: results from the RAPIDS-2 randomised, double-blind, placebo-controlled trial

(2010) M. Matucci-Cerinic et al.   ANNALS OF THE RHEUMATIC DISEASES

Endothelin—Biology and disease

(2010) Al-karim Khimji et al.   CELLULAR SIGNALLING

Short and long term anti-inflammatory effects of bosentan therapy in patients with pulmonary arterial hypertension: relation to clinical and hemodynamic responses

(2010) George K Karavolias et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Inflammatory cytokines in vascular dysfunction and vascular disease

(2009) Alexander H. Sprague et al.   BIOCHEMICAL PHARMACOLOGY

Transcriptional regulation of monocyte chemotactic protein-1 release by endothelin-1 in human airway smooth muscle cells involves NF-κB and AP-1

(2009) Amy M Sutcliffe et al.   BRITISH JOURNAL OF PHARMACOLOGY

Endothelin receptor selectivity: evidence fromin vitroand pre-clinical models of scleroderma

(2009) X. Shiwen et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Regulation of endothelin-1-induced interleukin-6 production by Ca2+ influx in human airway smooth muscle cells

(2009) Susumu Iwata et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Scleroderma

(2009) Armando Gabrielli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Endothelin receptor A expression in human inflammatory cells

(2009) M. Mencarelli et al.   REGULATORY PEPTIDES

Ambrisentan

(2008) Jamie D Croxtall et al.   DRUGS

Endothelin (ET)-1 Inhibits Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activity in Human Abdominal Aortic Endothelial Cells: A Novel Function of ETB1Receptors

(2008) Jagadeesha K. Dammanahalli et al.   ENDOCRINOLOGY

Inflammatory responses after endothelin B (ETB) receptor activation in human monocytes: New evidence for beneficial anti-inflammatory potency of ETB-receptor antagonism

(2008) Uwe R. Juergens et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Bosentan regulates the expression of adhesion molecules on circulating T cells and serum soluble adhesion molecules in systemic sclerosis-associated pulmonary arterial hypertension

(2007) F Iannone et al.   ANNALS OF THE RHEUMATIC DISEASES