Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines

Identification of sequence variants influencing immunoglobulin levels

(2017) Stefan Jonsson et al.   NATURE GENETICS

Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections

(2017) Chao Tian et al.   Nature Communications

Reference-based phasing using the Haplotype Reference Consortium panel

(2016) Po-Ru Loh et al.   NATURE GENETICS

A reference panel of 64,976 haplotypes for genotype imputation

(2016)   NATURE GENETICS

How sex and age affect immune responses, susceptibility to infections, and response to vaccination

(2015) Carmen Giefing-Kröll et al.   AGING CELL

Amino Acid Variation in HLA Class II Proteins Is a Major Determinant of Humoral Response to Common Viruses

(2015) Christian Hammer et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Imputation of KIR Types from SNP Variation Data

(2015) Damjan Vukcevic et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Milieu Intérieur study — An integrative approach for study of human immunological variance

(2015) Stéphanie Thomas et al.   CLINICAL IMMUNOLOGY

Genome-wide genetic investigation of serological measures of common infections

(2015) Rohina Rubicz et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The higher frequency of IgA deficiency among Swedish twins is not explained by HLA haplotypes

(2015) M Frankowiack et al.   GENES AND IMMUNITY

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load

(2015) Paul J. McLaren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma

(2015) Bhairavi Swaminathan et al.   Nature Communications

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses

(2014) John S. Tsang et al.   CELL

IgA measurements in over 12 000 Swedish twins reveal sex differential heritability and regulatory locus near CD30L

(2014) Alexander Viktorin et al.   HUMAN MOLECULAR GENETICS

Long-chain Acyl-CoA Dehydrogenase Deficiency as a Cause of Pulmonary Surfactant Dysfunction

(2014) Eric S. Goetzman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polymorphisms in HLA-DPB1 Are Associated With Differences in Rubella Virus-Specific Humoral Immunity After Vaccination

(2014) N. D. Lambert et al.   JOURNAL OF INFECTIOUS DISEASES

Efficient multivariate linear mixed model algorithms for genome-wide association studies

(2014) Xiang Zhou et al.   NATURE METHODS

Combined Linkage and Association Studies Show that HLA Class II Variants Control Levels of Antibodies against Epstein-Barr Virus Antigens

(2014) Vincent Pedergnana et al.   PLoS One

A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness

(2014) Jared O'Connell et al.   PLoS Genetics

Sequence Kernel Association Tests for the Combined Effect of Rare and Common Variants

(2013) Iuliana Ionita-Laza et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Genetic Theory of Infectious Diseases: A Brief History and Selected Illustrations

(2013) Jean-Laurent Casanova et al.   Annual Review of Genomics and Human Genetics

Identification of Genetic Loci Associated With Helicobacter pylori Serologic Status

(2013) Julia Mayerle et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Imputing Amino Acid Polymorphisms in Human Leukocyte Antigens

(2013) Xiaoming Jia et al.   PLoS One

Systematic Review and Meta-Analysis of the Sero-Epidemiological Association between Epstein Barr Virus and Multiple Sclerosis

(2013) Yahya H. Almohmeed et al.   PLoS One

A Genome-Wide Integrative Genomic Study Localizes Genetic Factors Influencing Antibodies against Epstein-Barr Virus Nuclear Antigen 1 (EBNA-1)

(2013) Rohina Rubicz et al.   PLoS Genetics

Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls

(2013) Paul J. McLaren et al.   PLoS Pathogens

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Genome-wide association study identifies common variants at TNFRSF13B associated with IgG level in a healthy Chinese male population

(2012) M Liao et al.   GENES AND IMMUNITY

Genome-wide association study identifies TNFSF13 as a susceptibility gene for IgA in a South Chinese population in smokers

(2012) Chen Yang et al.   IMMUNOGENETICS

Genome-wide association study indicates two novel resistance loci for severe malaria

(2012) Christian Timmann et al.   NATURE

Genome-Wide Scan Identifies Variant in TNFSF13 Associated with Serum IgM in a Healthy Chinese Male Population

(2012) Ming Yang et al.   PLoS One

Virus reactivation: a panoramic view in human infections

(2011) Christopher M Traylen et al.   Future Virology

Genetic Factors Influence Serological Measures of Common Infections

(2011) Rohina Rubicz et al.   HUMAN HEREDITY

Robust relationship inference in genome-wide association studies

(2010) Ani Manichaikul et al.   BIOINFORMATICS

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Stability selection

(2010) Nicolai Meinshausen et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

The Xs and Y of immune responses to viral vaccines

(2010) Sabra L Klein et al.   LANCET INFECTIOUS DISEASES

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

(2009) Dongliang Ge et al.   NATURE

Gender effects on humoral immune responses to smallpox vaccine

(2009) Richard B. Kennedy et al.   VACCINE

Human Leukocyte Antigen and Cytokine Receptor Gene Polymorphisms Associated With Heterogeneous Immune Responses to Mumps Viral Vaccine

(2008) I. G. Ovsyannikova et al.   PEDIATRICS

Sexual dimorphism of humoral immunity with human vaccines

(2008) Ian Francis Cook   VACCINE