Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre- and post-synaptic 5-HT1A receptor expression

Antidepressant Treatment Reduces Serotonin-1A Autoreceptor Binding in Major Depressive Disorder

(2013) Neil A. Gray et al.   BIOLOGICAL PSYCHIATRY

Postnatal Fluoxetine-Evoked Anxiety Is Prevented by Concomitant 5-HT2A/C Receptor Blockade and Mimicked by Postnatal 5-HT2A/C Receptor Stimulation

(2013) Ambalika Sarkar et al.   BIOLOGICAL PSYCHIATRY

Genetic approaches for understanding the role of serotonin receptors in mood and behavior

(2013) Zoe R Donaldson et al.   CURRENT OPINION IN NEUROBIOLOGY

Serotonin 1A auto-receptors are not sufficient to modulate anxiety in mice

(2013) Lukasz Piszczek et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Protein kinase C regulates tonic GABAAreceptor-mediated inhibition in the hippocampus and thalamus

(2013) Damian P. Bright et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

DEAF1 Is a Pellino1-interacting Protein Required for Interferon Production by Sendai Virus and Double-stranded RNA

(2013) Alban Ordureau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of Serotonin Neuron Firing Increases Aggression in Mice

(2013) E. Audero et al.   JOURNAL OF NEUROSCIENCE

Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010

(2013) Harvey A Whiteford et al.   LANCET

Developmental Effects of Serotonin 1A Autoreceptors on Anxiety and Social Behavior

(2013) Zoe R Donaldson et al.   NEUROPSYCHOPHARMACOLOGY

Imaging the serotonin 1A receptor using [11C]WAY100635 in healthy controls and major depression

(2013) N. Hesselgrave et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The serotonergic system in mood disorders and suicidal behaviour

(2013) J. J. Mann   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

P5-HT1A receptors in mood and anxiety: recent insights into autoreceptor versus heteroreceptor function

(2013) Alvaro L. Garcia-Garcia et al.   PSYCHOPHARMACOLOGY

The effects of congenital brain serotonin deficiency on responses to chronic fluoxetine

(2013) B D Sachs et al.   Translational Psychiatry

Preclinical Studies Modeling Deep Brain Stimulation for Depression

(2012) Clement Hamani et al.   BIOLOGICAL PSYCHIATRY

Ketamine for Depression: Where Do We Go from Here?

(2012) Marije aan het Rot et al.   BIOLOGICAL PSYCHIATRY

17β-Estradiol-Induced Regulation of the Novel 5-HT1A-Related Transcription Factors NUDR and Freud-1 in SH SY5Y Cells

(2012) Samuel O. Adeosun et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Serotonin Receptors as Targets for Drugs Useful to Treat Psychosis and Cognitive Impairment in Schizophrenia

(2012) H. Y. Meltzer et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The serotonin 1A receptor gene confer susceptibility to mood disorders: results from an extended meta-analysis of patients with major depression and bipolar disorder

(2012) Taro Kishi et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Increased Serotonin-1A (5-HT1A) Autoreceptor Expression and Reduced Raphe Serotonin Levels in Deformed Epidermal Autoregulatory Factor-1 (Deaf-1) Gene Knock-out Mice

(2012) Margaret Czesak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association of serotonin-1A and -2A receptor promoter polymorphisms with depressive symptoms, functional recovery, and pain in patients 6 months after lumbar disc surgery

(2012) Moritz Lebe et al.   PAIN

Transcriptional regulation of the 5-HT1A receptor: implications for mental illness

(2012) P. R. Albert   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Targeting brain serotonin synthesis: insights into neurodevelopmental disorders with long-term outcomes related to negative emotionality, aggression and antisocial behaviour

(2012) K.-P. Lesch et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The 5-HT deficiency theory of depression: perspectives from a naturalistic 5-HT deficiency model, the tryptophan hydroxylase 2Arg439His knockin mouse

(2012) J. P. R. Jacobsen et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A neurotrophic hypothesis of depression: role of synaptogenesis in the actions of NMDA receptor antagonists

(2012) R. S. Duman et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior

(2012) J. Veenstra-VanderWeele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acute 5-HT1A autoreceptor knockdown increases antidepressant responses and serotonin release in stressful conditions

(2012) Albert Ferrés-Coy et al.   PSYCHOPHARMACOLOGY

Exaggerated aggression and decreased anxiety in mice deficient in brain serotonin

(2012) V Mosienko et al.   Translational Psychiatry

Serotonin 1A receptor-mediated signaling through ERK and PKCα is essential for normal synaptogenesis in neonatal mouse hippocampus

(2012) A Mogha et al.   Translational Psychiatry

Deep Brain Stimulation for Psychiatric Disorders

(2011) Paul E. Holtzheimer et al.   Annual Review of Neuroscience

The Serotonin Transporter Promoter Variant (5-HTTLPR), Stress, and Depression Meta-analysis Revisited

(2011) Katja Karg et al.   ARCHIVES OF GENERAL PSYCHIATRY

5-HT1A Receptor Agonists Enhance Pyramidal Cell Firing in Prefrontal Cortex Through a Preferential Action on GABA Interneurons

(2011) L. Llado-Pelfort et al.   CEREBRAL CORTEX

Projections and interconnections of genetically defined serotonin neurons in mice

(2011) Sun Jung Bang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Association of the C(−1019)G 5-HT1A promoter polymorphism with exposure to stressors preceding hospitalization for bipolar depression

(2011) Francesco Benedetti et al.   JOURNAL OF AFFECTIVE DISORDERS

Serotonin-1A Autoreceptors Are Necessary and Sufficient for the Normal Formation of Circuits Underlying Innate Anxiety

(2011) J. W. Richardson-Jones et al.   JOURNAL OF NEUROSCIENCE

Serotonin and Prefrontal Cortex Function: Neurons, Networks, and Circuits

(2011) M. Victoria Puig et al.   MOLECULAR NEUROBIOLOGY

Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice

(2011) J P R Jacobsen et al.   MOLECULAR PSYCHIATRY

Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects

(2011) A Bortolozzi et al.   MOLECULAR PSYCHIATRY

Polymorphic variation at the serotonin 1-A receptor gene is associated with comorbid depression and generalized anxiety

(2011) Esther Molina et al.   PSYCHIATRIC GENETICS

Genetic Sensitivity to the Environment: The Case of the Serotonin Transporter Gene and Its Implications for Studying Complex Diseases and Traits

(2010) Avshalom Caspi et al.   AMERICAN JOURNAL OF PSYCHIATRY

Flexible Accelerated STOP Tetracycline Operator-Knockin (FAST): A Versatile and Efficient New Gene Modulating System

(2010) Kenji F. Tanaka et al.   BIOLOGICAL PSYCHIATRY

Preferential in vivo action of F15599, a novel 5-HT1A receptor agonist, at postsynaptic 5-HT1A receptors

(2010) L Lladó-Pelfort et al.   BRITISH JOURNAL OF PHARMACOLOGY

Freud-2/CC2D1B mediates dual repression of the serotonin-1A receptor gene

(2010) Mahmoud R. Hadjighassem et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The HTR1A and HTR1B receptor genes influence stress-related information processing

(2010) Krisztina Mekli et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Decreased expression of Freud-1/CC2D1A, a transcriptional repressor of the 5-HT1A receptor, in the prefrontal cortex of subjects with major depression

(2010) Bernadeta Szewczyk et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Cortisol plasma levels in social anxiety disorder patients correlate with serotonin-1A receptor binding in limbic brain regions

(2010) Rupert Lanzenberger et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Enhanced Function of Prefrontal Serotonin 5-HT2 Receptors in a Rat Model of Psychiatric Vulnerability

(2010) M. Benekareddy et al.   JOURNAL OF NEUROSCIENCE

Pet-1 is required across different stages of life to regulate serotonergic function

(2010) Chen Liu et al.   NATURE NEUROSCIENCE

5-HT1A Autoreceptor Levels Determine Vulnerability to Stress and Response to Antidepressants

(2010) Jesse W. Richardson-Jones et al.   NEURON

Brain Serotonin Synthesis in Adult Males Characterized by Physical Aggression during Childhood: A 21-Year Longitudinal Study

(2010) Linda Booij et al.   PLoS One

ErbB4 in parvalbumin-positive interneurons is critical for neuregulin 1 regulation of long-term potentiation

(2010) Y.-J. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modifying 5-HT1A receptor gene expression as a new target for antidepressant therapy

(2010) Albert   Frontiers in Neuroscience

Human Freud-2/CC2D1B: A Novel Repressor of Postsynaptic Serotonin-1A Receptor Expression

(2009) Mahmoud R. Hadjighassem et al.   BIOLOGICAL PSYCHIATRY

The Serotonin-1A Receptor in Anxiety Disorders

(2009) Elena Akimova et al.   BIOLOGICAL PSYCHIATRY

Neurobiological mechanisms in major depressive disorder

(2009) M. aan het Rot et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

GABAB Receptors, Schizophrenia and Sleep Dysfunction

(2009) Joshua Kantrowitz et al.   CNS DRUGS

Use of latency to immobility improves detection of antidepressant-like activity in the behavioral despair test in the mouse

(2009) Vincent Castagné et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Layer II/III of the Prefrontal Cortex: Inhibition by the Serotonin 5-HT1A Receptor in Development and Stress

(2009) N. M. Goodfellow et al.   JOURNAL OF NEUROSCIENCE

Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes

(2009) Linda Yip et al.   NATURE IMMUNOLOGY

Linking Genetically Defined Neurons to Behavior through a Broadly Applicable Silencing Allele

(2009) Jun Chul Kim et al.   NEURON

Differential regulation of the serotonin 1 A transcriptional modulators five prime repressor element under dual repression-1 and nuclear-deformed epidermal autoregulatory factor by chronic stress

(2009) A.H. Iyo et al.   NEUROSCIENCE

5-HT1A receptor function in major depressive disorder

(2009) Jonathan Savitz et al.   PROGRESS IN NEUROBIOLOGY

No association between the serotonin-1A receptor gene single nucleotide polymorphism rs6295C/G and symptoms of anxiety or depression, and no interaction between the polymorphism and environmental stressors of childhood anxiety or recent stressful life events on anxiety or depression

(2009) Phillip Chipman et al.   PSYCHIATRIC GENETICS

Fast Synaptic Subcortical Control of Hippocampal Circuits

(2009) V. Varga et al.   SCIENCE

Calcium-Sensitive Adenylyl Cyclases in Depression and Anxiety: Behavioral and Biochemical Consequences of Isoform Targeting

(2008) Vaishnav Krishnan et al.   BIOLOGICAL PSYCHIATRY

Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder

(2008) Bernadeta Szewczyk et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Activation of 5-HT2A/CReceptors Counteracts 5-HT1ARegulation ofN-Methyl-D-aspartate Receptor Channels in Pyramidal Neurons of Prefrontal Cortex

(2008) Eunice Y. Yuen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serotonin 1A receptors in human and monkey prefrontal cortex are mainly expressed in pyramidal neurons and in a GABAergic interneuron subpopulation: implications for schizophrenia and its treatment

(2008) Julián De Almeida et al.   JOURNAL OF NEUROCHEMISTRY

HES1 regulates 5-HT1A receptor gene transcription at a functional polymorphism: Essential role in developmental expression

(2008) Kirsten X. Jacobsen et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The molecular neurobiology of depression

(2008) Vaishnav Krishnan et al.   NATURE

Behavioral Phenotyping Strategies for Mutant Mice

(2008) Jacqueline N. Crawley   NEURON

Transcriptional regulation at a HTR1A polymorphism associated with mental illness

(2008) Brice Le François et al.   NEUROPHARMACOLOGY

Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease

(2008) Andrew Holmes   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Corticosteroid–serotonin interactions in the neurobiological mechanisms of stress-related disorders

(2008) Laurence Lanfumey et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS