Article
Microbiology
Rhonda Walters, Allison Campolo, Elise Miller, Cindy McAnally, Manal Gabriel, Paul Shannon, Monica Crary
Summary: The efficacy of preservative-free disinfection systems against bacteria, fungi, and Acanthamoeba was evaluated. Clear Care and Clear Care Plus showed significantly greater disinfection efficacy against Acanthamoeba compared to the povidone-iodine-based Cleadew system. The antimicrobial efficacy was maintained regardless of the presence of contact lenses.
MICROBIOLOGY SPECTRUM
(2022)
Article
Ophthalmology
Katsuhide Yamasaki, Yohei Mizuno, Yoshiyuki Kitamura, David J. McCanna, William Ngo, Lyndon W. Jones
Summary: All three solutions significantly reduced P. aeruginosa on direct-contact surfaces. The PVP-I system was more effective against P. aeruginosa on non-contact surfaces than the hydrogen peroxide system or the chemical multipurpose system, and capable of inhibiting regrowth of P. aeruginosa for at least 7 days post-disinfection.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Allergy
Susann Forkel, Caroline Beutner, Katharina Amschler, Silke Sabina Schroeder, Michael P. Schoen, Johannes Geier, Timo Buhl
Summary: Patch testing with PVP-I 2% aq. showed the lowest number of doubtful skin reactions while detecting the single allergic patient, suggesting it as the optimal preparation for iodine patch tests. Overestimation of iodine allergy was indicated, and positive patch test responses to iodine should be confirmed with ROATs before diagnosis.
CONTACT DERMATITIS
(2021)
Article
Agriculture, Dairy & Animal Science
Maurizio Isola, Cristina Piccinotti, Massimiliano Magro, Luca Fasolato, Fabio Vianello, Maria Luisa Menandro, Parastoo Memarian, Melissa Rossi, Maria Elena Falomo
Summary: Horse hooves can be susceptible to secondary infections, and effective disinfectants are crucial in preventing such complications. IA demonstrated strong bactericidal activity in vitro and enhanced the effectiveness of CHx and PI in hoof disinfection, showing potential applications in pre-surgical procedures for reducing infection risks.
Article
Ophthalmology
Muhammad Yasir, Ajay Kumar Vijay, Mark Willcox
Summary: The study demonstrates that oxidative contact lens disinfecting solutions containing povidone iodine or hydrogen peroxide exhibit superior antiviral activity against a coronavirus surrogate of SARS-CoV-2, especially when the full regimen test is used.
CONTACT LENS & ANTERIOR EYE
(2022)
Article
Ophthalmology
Sin Wan Cheung, Maureen Valerie Boost, Pauline Cho
Summary: The study found that using a povidone iodine-based rigid lens disinfecting solution effectively reduced contamination rates of lenses and lens cases and conjunctival colonization. Regardless of the cleaning routine adopted, there were no significant differences observed in conjunctival colonization or contamination of lenses or cases.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Pauline Cho, Maureen Valerie Boost, Sin Wan Cheung
Summary: This study aimed to determine whether the use of a povidone iodine (PI) disinfecting system in new orthokeratology (ortho-k) subjects is associated with changes in ocular symptoms and signs compared to before lens wear, and whether these changes are related to cleaning regimes. The results showed that the use of a PI-based solution did not increase the frequency or severity of ocular signs and symptoms observed before lens wear, indicating that the PI-based solution can adequately clean the lenses over a 6-month period.
CONTACT LENS & ANTERIOR EYE
(2023)
Review
Ophthalmology
Ana Gomes de Lacerda, Madalena Lira
Summary: Acanthamoeba keratitis is a widespread infection caused by a unicellular protozoan that mainly affects contact lens wearers and is linked to corneal trauma as well. It is essential to deepen the understanding of risk factors, focus on prevention strategies, and enhance the efficacy of disinfection systems to minimize the risk of infection. Additionally, there is a need for the development of effective diagnostic methods and treatments for this type of corneal infection in the near future.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Microbiology
Yu-Jen Wang, Sung-Chou Li, Wei-Chen Lin, Fu-Chin Huang
Summary: This study reveals the abundant anaerobic Gram-positive rods present in severe keratitis isolate and characterizes the association between Acanthamoeba and ocular flora in AK progression. Further analysis shows that Blautia producta is positively correlated with the disease course, while Bacteroides ovatus is abundant in early-stage keratitis isolates.
Article
Microbiology
Allison Campolo, Reed Pifer, Rhonda Walters, Megan Thomas, Elise Miller, Valerie Harris, Jamie King, Christopher A. Rice, Paul Shannon, Brian Patterson, Monica Crary
Summary: This study found that certain contact lens materials can promote the aggregation and encystment of Acanthamoeba, and that Acanthamoeba spheroids obstruct the disinfection action of multi-purpose solutions.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Allison Campolo, Brian Patterson, Esther Lara, Paul Shannon, Monica Crary
Summary: Acanthamoeba keratitis is a challenging infection of the cornea, and understanding the behavior of Acanthamoebae during contact lens use and disinfection can provide insights into their colonization and the efficacy of contact lens care solutions. In this study, Acanthamoeba behavior during and after disinfection with different contact lens care solutions was examined. The results showed that all contact lens care solutions significantly impacted Acanthamoeba motility, with the solution containing PHMB showing the most effectiveness. Post-disinfection, Acanthamoebae were observed to regain motility and travel considerable distances, posing a potential risk to ocular health.
Article
Surgery
Rod J. Rohrich, Jasson T. Abraham, Brendan Alleyne, Justin Bellamy
Summary: This article describes simple preventative strategies during rhinoplasty procedures to minimize the risk of disease transmission, particularly discussing the use of povidone-iodine in prophylaxis during the perioperative period.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2022)
Article
Microbiology
Edyta B. Hendiger, Marcin Padzik, Ines Sifaoui, Maria Reyes-Batlle, Atteneri Lopez-Arencibia, Diana Zyskowska, Marta Grodzik, Anna Pietruczuk-Padzik, Jacek Hendiger, Gabriela Oledzka, Lidia Chomicz, Jose E. Pinero, Jacob Lorenzo-Morales
Summary: Acanthamoeba keratitis is a severe corneal infection that can be effectively reduced by incorporating silver nanoparticles into contact lens solutions without increasing cytotoxicity.
Article
Microbiology
Marcin Padzik, Lidia Chomicz, Julita Bluszcz, Karolina Maleszewska, Jaroslaw Grobelny, David Bruce Conn, Edyta B. Hendiger
Summary: Acanthamoeba spp. can cause Acanthamoeba keratitis, particularly in contact lens wearers. It has been found that silver nanoparticles combined with tannic acid-modified contact lens solutions can enhance their anti-adhesion activity with low cytotoxicity.
Article
Chemistry, Multidisciplinary
Yanling You, Ya-Xuan Zhu, Junjie Jiang, Zhixin Chen, Chenyao Wu, Zhimin Zhang, Han Lin, Jianlin Shi
Summary: In this study, a new two-dimensional iodine nanomaterial called iodinene was proposed for the treatment of infectious diseases in vivo. Iodinene demonstrated enhanced antibacterial efficacy against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa by in situ production of active HIO and I2 molecules via allotropic transformation. The in vivo results further confirmed the desirable antibacterial efficacy of iodinene in treating bacterial wound infection and pneumonia.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Ophthalmology
Pauline Cho, Hoi Ying Poon, Chia Ching Chen, Lien Tao Yuon
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2020)
Article
Ophthalmology
Qi Tan, Alex L. K. Ng, Bonnie N. K. Choy, George P. M. Cheng, Victor C. P. Woo, Pauline Cho
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2020)
Article
Ophthalmology
Bi Yang, Xueqin Ma, Longqian Liu, Pauline Cho
Summary: The study found that Chinese children wearing orthokeratology lenses had significantly better scores in overall vision, far vision, appearance, satisfaction, activities, and peer perceptions compared to those wearing single vision spectacles. Although some ocular discomfort may occur when wearing ortho-k lenses at night, the benefits outweigh the discomfort, resulting in better vision-related quality of life for Chinese children.
CONTACT LENS & ANTERIOR EYE
(2021)
Review
Ophthalmology
Xingyu Wang, Bi Yang, Longqian Liu, Pauline Cho
Summary: The main motivation for parents to choose ortho-k for their children was the rapid progression of myopia, with most learning about ortho-k through word of mouth. The most common symptom during treatment was itchy or sore eyes, usually only initially. Children's willingness to participate is crucial for successful ortho-k treatment, even though their motivation may differ from that of their parents. Ortho-k is widely accepted as an option for myopia control in children.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Ophthalmology
Stephen J. Vincent, Qi Tan, Alex L. K. Ng, George P. M. Cheng, Victor C. P. Woo, Pauline Cho
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2020)
Article
Ophthalmology
Qi Tan, Alex L. K. Ng, George P. M. Cheng, Victor C. P. Woo, Pauline Cho
Summary: The study found that pupil size measurements using the NIDEK OPD-Scan III were highly repeatable in myopic children, making it suitable for use in this population.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Ophthalmology
Sin Wan Cheung, Maureen Valerie Boost, Pauline Cho
Summary: The study found that using a povidone iodine-based rigid lens disinfecting solution effectively reduced contamination rates of lenses and lens cases and conjunctival colonization. Regardless of the cleaning routine adopted, there were no significant differences observed in conjunctival colonization or contamination of lenses or cases.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Biyue Guo, Pauline Cho, Nathan Efron
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2021)
Article
Ophthalmology
Kin Wan, Hing Tuen Yau, Sin Wan Cheung, Pauline Cho
Summary: This study evaluated thickness changes in different layers of the cornea in myopic children during and after short-term ortho-k lens wear. The results showed significant reductions in CET with higher reduction in eyes wearing ICF lenses, while corneal thickness changes were reversible after discontinuing lens wear.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Ophthalmology
Biyue Guo, Sin Wan Cheung, Randy Kojima, Pauline Cho
Summary: The 1-year results of the VOLTZ Study show that orthokeratology lenses with different back optic zone diameters have a varying effect on myopia control in children. Using lenses with a 5mm BOZD can lead to slower axial elongation, while maintaining similar lens performance and ocular integrity compared to lenses with a 6mm BOZD.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Ophthalmology
Yajing Yang, Sin Wan Cheung, Pauline Cho, Stephen J. Vincent
Summary: The study found that the estimated myopia progression by the BHVI Myopia Calculator was in close agreement with the actual measured values after 1 and 2 years, but caution is advised when interpreting the data as it only fell within the 95% confidence interval for a relatively small percentage of children.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Infectious Diseases
Zhi Chen, Jifang Wang, Jun Jiang, Bi Yang, Pauline Cho
Summary: This study investigated the impact of guidelines on the knowledge, attitude, and prescribing habits of ortho-k practitioners. The findings showed that the implementation of the guidelines significantly improved the overall prescribing habits, but some practitioners still need to improve their behavior.
Article
Ophthalmology
Biyue Guo, Huihuan Wu, Sin Wan Cheung, Pauline Cho
Summary: This study compared the treatment zone measurements obtained using manual and software-based methods in orthokeratology subjects. The results showed significant differences between the two methods, suggesting that they cannot be used interchangeably. The study also found significant differences in treatment zone parameters between slow and fast axial elongation subjects, indicating a potential role of the treatment zone in regulating myopia progression in ortho-k.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2022)
Article
Ophthalmology
Bi Yang, Longqian Liu, Pauline Cho
Summary: This study investigated the compliance of orthokeratology wearers and their parents with care routines in a hospital setting in Chengdu, China. The results showed that parental supervision and instructions from eye care practitioners were important factors in increasing compliance. Regular reinforcement of care procedures, especially for older and male wearers, is crucial.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2022)
Article
Ophthalmology
Biyue Guo, Sin Wan Cheung, Randy Kojima, Pauline Cho
Summary: The purpose of this study was to compare the axial elongation (AE) and treatment zone (TZ) characteristics in children wearing 6 mm or 5 mm orthokeratology lenses over 2 years. The results showed that children wearing 5 mm lenses had a smaller TZ diameter and less AE after 24 months of treatment, with no difference in choroidal thickness changes. In conclusion, using orthokeratology lenses with a smaller back optic zone diameter can slow down axial elongation in children.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
