Article
Public, Environmental & Occupational Health
Yuzhuo Fan, Lili Zuo, Jiahui Ma, Zisu Peng, Yan Li, Kai Wang, Mingwei Zhao
Summary: This study investigated the reasons for wasting orthokeratology lenses due to breakage or loss. It found that caregiver behavior, care practices, and unexpected situations were the main causes. Better clinical guidance and more frequent reminders could prevent a large proportion of abnormal waste of orthokeratology lenses.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Ophthalmology
Jason K. Lau, Kin Wan, Pauline Cho
Summary: The study aimed to investigate the effectiveness of orthokeratology (ortho-k) lenses for myopia control and the corneal changes with increased compression factor. The findings showed that ortho-k lenses with increased compression factor can effectively slow down the progression of myopia without compromising corneal health. Further research is needed to confirm the potential mechanism of an increased compression factor for improved myopia control effectiveness.
CONTACT LENS & ANTERIOR EYE
(2023)
Article
Ophthalmology
Erin S. Tomiyama, David A. Berntsen, Kathryn Richdale
Summary: This study aimed to compare the effects of toric orthokeratology (TOK) and soft toric multifocal (STM) contact lenses on peripheral refraction in patients with astigmatism and myopia. The results showed that TOK induced greater myopic shift and astigmatism compared to STM, which may impact the efficacy of myopia management.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Review
Ophthalmology
Kelsea V. Skidmore, Erin S. Tomiyama, Martin E. Rickert, Kathryn Richdale, Pete Kollbaum
Summary: This study evaluated the relative efficacy of peripheral defocus contact lenses (PDCLs) and orthokeratology (OK) in a real-world clinical population and compared the results with previous randomised controlled clinical trials. The study found no difference in annualised axial length growth between PDCL and OK. These results are consistent with those reported in randomised clinical trials. Therefore, further research is needed to understand the safety and efficacy of these myopia control treatments in the broader population.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)
Article
Medicine, General & Internal
Jian Qin, Huiling Qing, Na Ji, Tianbin Lyu, Hui Ma, Menghai Shi, Shiao Yu, Conghui Ma, Aicun Fu
Summary: Unilateral orthokeratology lenses effectively reduced axial elongation in the more myopic eyes and reduced interocular AL differences in children with myopic anisometropia. The refractive state of the untreated eyes did not affect the axial elongation of the more myopic eye wearing the orthokeratology lens. In the untreated eyes, AL increased faster in the low myopia subgroup than in the emmetropia subgroup.
FRONTIERS IN MEDICINE
(2023)
Article
Cell Biology
Li Li, Taichen Lai, Jing Zou, Linling Guo, Zhiming Lin, Jiawen Lin, Ying Xue
Summary: This study investigated the effects of an orthokeratology lens on tear film and tarsal glands, as well as myopia control in children with unilateral myopia, using an intelligent analysis model. The study found that tear film break-up times differed significantly in the treatment group, and there were also significant differences in the deformation coefficients of the meibomian glands. In contrast, the control group showed no significant differences.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Medicine, General & Internal
Jaume Paune, Silvia Fonts, Lina Rodriguez, Antonio Queiros
Summary: This study compared the efficacy of controlling the annual increase in axial length in myopic children based on different parameters, finding that a smaller back optic zone diameter and a smaller plus power ring diameter inside the pupil were more effective in slowing down the elongation of the eye. The results provide new insights for changing myopia treatment methods and designs.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Ophthalmology
Zhi Chen, Zhe Zhang, Feng Xue, Jiaqi Zhou, Li Zeng, Xiaomei Qu, Xingtao Zhou
Summary: This study investigated the relationship between myopia progression and axial length elongation in orthokeratology patients. The results showed that myopia significantly progressed and axial length increased after ortho-k treatment, and this progression was related to changes in corneal curvature, baseline age, and duration of treatment.
CONTACT LENS & ANTERIOR EYE
(2023)
Article
Ophthalmology
Trine Moldrup Jakobsen, Flemming Moller
Summary: The study on myopia control and orthokeratology lenses in a Danish population showed that orthokeratology lenses can significantly reduce axial elongation without significant vision-threatening adverse events, which is consistent with previous clinical trials.
ACTA OPHTHALMOLOGICA
(2022)
Article
Clinical Neurology
Xiaohang Chen, Yan Xiong, Xinzhou Qi, Longqian Liu
Summary: The objective of this study was to observe the changes in peripheral refraction in myopic adolescents after overnight orthokeratology and its influencing factors. The results showed that after wearing orthokeratology lenses, the relative peripheral refraction in myopic patients changed from relative hyperopia to relative myopia, and the nasal-temporal asymmetry also changed significantly. This change was correlated with the baseline refractive state.
FRONTIERS IN NEUROLOGY
(2023)
Article
Ophthalmology
Stephen J. Vincent, Pauline Cho, Ka Yin Chan, Daddi Fadel, Neema Ghorbani-Mojarrad, Jose M. Gonzalez-Meijome, Leah Johnson, Pauline Kang, Langis Michaud, Patrick Simard, Lyndon Jones
Summary: Orthokeratology is a method of temporarily reshaping the cornea using specialty contact lenses to correct refractive errors, and has been increasingly used to slow the progression of myopia in children. This report reviews the practice of ortho-k, including safety considerations, suitable candidates, and key factors such as lens design.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Jost B. Jonas, Marcus Ang, Pauline Cho, Jeremy A. Guggenheim, Ming Guang He, Monica Jong, Nicola S. Logan, Maria Liu, Ian Morgan, Kyoko Ohno-Matsui, Olavi Parssinen, Serge Resnikoff, Padmaja Sankaridurg, Seang-Mei Saw, Earl L. Smith, Donald T. H. Tan, Jeffrey J. Walline, Christine F. Wildsoet, Pei-Chang Wu, Xiaoying Zhu, James S. Wolffsohn
Summary: The prevalence of myopia is increasing in East and Southeast Asia, with strategies needed to reduce its progression. Encouraging outdoor activities and using low-dose atropine eye drops are beneficial measures for reducing myopia development. Individual risk-to-benefit ratios need to be considered for different treatment options based on age, health, and lifestyle.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Article
Ophthalmology
Xue Li, Yingying Huang, Jiali Zhang, Chenglu Ding, Yunyun Chen, Hao Chen, Jinhua Bao
Summary: The study found that greater TZ decentration with the use of OK lenses was associated with slower axial growth and a more oblate retinal shape. This type of decentration caused local defocusing changes, which may inhibit myopic progression.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2022)
Article
Ophthalmology
Na Li, Weiping Lin, Ruixue Liang, Ziwen Sun, Bei Du, Ruihua Wei
Summary: Different BOZD OK lenses, DISC lenses, and SCL lenses have certain effects in retarding axial elongation in 8-11-year-old myopes. 5.0 mm-BOZD OK lenses and DISC lenses have better control efficacy for low myopic eyes compared to single-vision SCLs or 6.2 mm-BOZD OK lenses.
Article
Ophthalmology
Jianxia Fang, Zhu Huang, Yan Long, Miaomiao Zhu, Qin Wu, Xiaojun Chen, Wei Xv, Chixin Du
Summary: This study compared the effectiveness of multifocal soft contact lenses (MFSCLs), orthokeratology contact lenses (Ortho-kCLs), and single vision spectacles (SVSs) for myopia control. The results showed that wearing MFSCLs and Ortho-kCLs significantly delayed myopia progression compared to SVSs.
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2022)
Article
Ophthalmology
Qi Tan, Alex L. K. Ng, Bonnie N. K. Choy, George P. M. Cheng, Victor C. P. Woo, Pauline Cho
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2020)
Article
Ophthalmology
Bi Yang, Xueqin Ma, Longqian Liu, Pauline Cho
Summary: The study found that Chinese children wearing orthokeratology lenses had significantly better scores in overall vision, far vision, appearance, satisfaction, activities, and peer perceptions compared to those wearing single vision spectacles. Although some ocular discomfort may occur when wearing ortho-k lenses at night, the benefits outweigh the discomfort, resulting in better vision-related quality of life for Chinese children.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Stephen J. Vincent, Qi Tan, Alex L. K. Ng, George P. M. Cheng, Victor C. P. Woo, Pauline Cho
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2020)
Article
Ophthalmology
Qi Tan, Alex L. K. Ng, George P. M. Cheng, Victor C. P. Woo, Pauline Cho
Summary: The study found that pupil size measurements using the NIDEK OPD-Scan III were highly repeatable in myopic children, making it suitable for use in this population.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Ophthalmology
Sin Wan Cheung, Maureen Valerie Boost, Pauline Cho
Summary: The study found that using a povidone iodine-based rigid lens disinfecting solution effectively reduced contamination rates of lenses and lens cases and conjunctival colonization. Regardless of the cleaning routine adopted, there were no significant differences observed in conjunctival colonization or contamination of lenses or cases.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Biyue Guo, Pauline Cho, Nathan Efron
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2021)
Article
Ophthalmology
Kin Wan, Hing Tuen Yau, Sin Wan Cheung, Pauline Cho
Summary: This study evaluated thickness changes in different layers of the cornea in myopic children during and after short-term ortho-k lens wear. The results showed significant reductions in CET with higher reduction in eyes wearing ICF lenses, while corneal thickness changes were reversible after discontinuing lens wear.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Ophthalmology
Biyue Guo, Sin Wan Cheung, Randy Kojima, Pauline Cho
Summary: The 1-year results of the VOLTZ Study show that orthokeratology lenses with different back optic zone diameters have a varying effect on myopia control in children. Using lenses with a 5mm BOZD can lead to slower axial elongation, while maintaining similar lens performance and ocular integrity compared to lenses with a 6mm BOZD.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Ophthalmology
Yajing Yang, Sin Wan Cheung, Pauline Cho, Stephen J. Vincent
Summary: The study found that the estimated myopia progression by the BHVI Myopia Calculator was in close agreement with the actual measured values after 1 and 2 years, but caution is advised when interpreting the data as it only fell within the 95% confidence interval for a relatively small percentage of children.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Infectious Diseases
Zhi Chen, Jifang Wang, Jun Jiang, Bi Yang, Pauline Cho
Summary: This study investigated the impact of guidelines on the knowledge, attitude, and prescribing habits of ortho-k practitioners. The findings showed that the implementation of the guidelines significantly improved the overall prescribing habits, but some practitioners still need to improve their behavior.
Article
Ophthalmology
Biyue Guo, Huihuan Wu, Sin Wan Cheung, Pauline Cho
Summary: This study compared the treatment zone measurements obtained using manual and software-based methods in orthokeratology subjects. The results showed significant differences between the two methods, suggesting that they cannot be used interchangeably. The study also found significant differences in treatment zone parameters between slow and fast axial elongation subjects, indicating a potential role of the treatment zone in regulating myopia progression in ortho-k.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2022)
Article
Ophthalmology
Bi Yang, Longqian Liu, Pauline Cho
Summary: This study investigated the compliance of orthokeratology wearers and their parents with care routines in a hospital setting in Chengdu, China. The results showed that parental supervision and instructions from eye care practitioners were important factors in increasing compliance. Regular reinforcement of care procedures, especially for older and male wearers, is crucial.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2022)
Article
Ophthalmology
Biyue Guo, Sin Wan Cheung, Randy Kojima, Pauline Cho
Summary: The purpose of this study was to compare the axial elongation (AE) and treatment zone (TZ) characteristics in children wearing 6 mm or 5 mm orthokeratology lenses over 2 years. The results showed that children wearing 5 mm lenses had a smaller TZ diameter and less AE after 24 months of treatment, with no difference in choroidal thickness changes. In conclusion, using orthokeratology lenses with a smaller back optic zone diameter can slow down axial elongation in children.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2023)