The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspective
出版年份 2012 全文链接
标题
The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspective
作者
关键词
-
出版物
Cell and Bioscience
Volume 2, Issue 1, Pages 28
出版商
Springer Nature
发表日期
2012-08-14
DOI
10.1186/2045-3701-2-28
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Wnt signaling in development and disease
- (2012) Yingzi Yang Cell and Bioscience
- Unraveling the role of FoxOs in bone—Insights from mouse models
- (2011) Maria Almeida BONE
- A novel mechanism for the transcriptional regulation of Wnt signaling in development
- (2011) T. Vacik et al. GENES & DEVELOPMENT
- Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism
- (2011) D. Savic et al. GENOME RESEARCH
- TCF7L2 splice variants have distinct effects on β-cell turnover and function
- (2011) Olivier Le Bacquer et al. HUMAN MOLECULAR GENETICS
- Glucocorticoids and Tumor Necrosis Factor α Increase Oxidative Stress and Suppress Wnt Protein Signaling in Osteoblasts
- (2011) Maria Almeida et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Osteoporosis: now and the future
- (2011) Tilman D Rachner et al. LANCET
- T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis
- (2011) M. L. Angus-Hill et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Wnt Signaling Regulates Hepatic Metabolism
- (2011) H. Liu et al. Science Signaling
- The genetics of type 2 diabetes: what have we learned from GWAS?
- (2010) Liana K. Billings et al. Annals of the New York Academy of Sciences
- Wnt Signaling and Aging-Related Heart Disorders
- (2010) Atsuhiko T. Naito et al. CIRCULATION RESEARCH
- The T-Allele of TCF7L2 rs7903146 Associates With a Reduced Compensation of Insulin Secretion for Insulin Resistance Induced by 9 Days of Bed Rest
- (2010) A. C. Alibegovic et al. DIABETES
- Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test
- (2010) A. P. Gjesing et al. DIABETOLOGIA
- Association testing of TCF7L2 polymorphisms with type 2 diabetes in multi-ethnic youth
- (2010) D. Dabelea et al. DIABETOLOGIA
- Can the Genetics of Type 1 and Type 2 Diabetes Shed Light on the Genetics of Latent Autoimmune Diabetes in Adults?
- (2010) Struan F. A. Grant et al. ENDOCRINE REVIEWS
- Open chromatin and diabetes risk
- (2010) Leif Groop NATURE GENETICS
- TCF7L2, dietary carbohydrate, and risk of type 2 diabetes in US women
- (2009) Marilyn C Cornelis et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Wnt5b stimulates adipogenesis by activating PPARγ, and inhibiting the β-catenin dependent Wnt signaling pathway together with Wnt5a
- (2009) F.H.J. van Tienen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- Type 2 Diabetes Susceptibility Gene TCF7L2 and Its Role in -Cell Function
- (2009) A. L. Gloyn et al. DIABETES
- TCF7L2 Regulates Late Events in Insulin Secretion From Pancreatic Islet -Cells
- (2009) G. da Silva Xavier et al. DIABETES
- WNT/β-catenin increases the production of incretins by entero-endocrine cells
- (2009) J. M. García-Martínez et al. DIABETOLOGIA
- Regulation of wingless-type MMTV integration site family (WNT) signalling in pancreatic islets from wild-type and obese mice
- (2009) J. Krützfeldt et al. DIABETOLOGIA
- The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men
- (2009) K. Pilgaard et al. DIABETOLOGIA
- Tissue-specific alternative splicing of TCF7L2
- (2009) Ludmila Prokunina-Olsson et al. HUMAN MOLECULAR GENETICS
- Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function
- (2009) Luan Shu et al. HUMAN MOLECULAR GENETICS
- Increased Lipid Oxidation Causes Oxidative Stress, Increased Peroxisome Proliferator-activated Receptor-γ Expression, and Diminished Pro-osteogenic Wnt Signaling in the Skeleton
- (2009) Maria Almeida et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Alternative Splicing of TCF7L2 Gene in Omental and Subcutaneous Adipose Tissue and Risk of Type 2 Diabetes
- (2009) Ludmila Prokunina-Olsson et al. PLoS One
- Expression of the transcription factor 7-like 2 gene (TCF7L2) in human adipocytes is down regulated by insulin
- (2008) Maja Ahlzén et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Wnt and beyond Wnt: Multiple mechanisms control the transcriptional property of β-catenin
- (2008) Tianru Jin et al. CELLULAR SIGNALLING
- Implication of Genetic Variants Near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in Type 2 Diabetes and Obesity in 6,719 Asians
- (2008) M. C.Y. Ng et al. DIABETES
- WNT signalling is both an inducer and effector of glucagon-like peptide-1
- (2008) B. Gustafson et al. DIABETOLOGIA
- The WNT signalling pathway and diabetes mellitus
- (2008) T. Jin DIABETOLOGIA
- Association of variants of the TCF7L2 gene with increases in the risk of type 2 diabetes and the proinsulin:insulin ratio in the Spanish population
- (2008) J. L. González-Sánchez et al. DIABETOLOGIA
- Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: Where are the insulin resistance genes?
- (2008) J. C. Florez DIABETOLOGIA
- Cross Talk between the Insulin and Wnt Signaling Pathways: Evidence from Intestinal Endocrine L Cells
- (2008) Fenghua Yi et al. ENDOCRINOLOGY
- Glucagon-like Peptide-1 Activation of TCF7L2-dependent Wnt Signaling Enhances Pancreatic Beta Cell Proliferation
- (2008) Zhengyu Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Minireview: The Wnt Signaling Pathway Effector TCF7L2 and Type 2 Diabetes Mellitus
- (2008) Tianru Jin et al. MOLECULAR ENDOCRINOLOGY
- Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes
- (2008) Valeriya Lyssenko et al. NEW ENGLAND JOURNAL OF MEDICINE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started