Article
Microbiology
In Young Choi, Jee-Hwan Oh, Zhiying Wang, Jan-Peter van Pijkeren
Summary: Biotherapeutic strategies, such as using engineered microbes to deliver therapeutic molecules, have great potential. However, the lack of precise tools to detect these microbes and their products hinders our ability to monitor and adjust therapeutic delivery. In this study, a bioluminescent peptide tagging system was adapted for lactic acid bacteria, which are commonly used as delivery vehicles for therapeutics. This system allowed sensitive detection of recombinant therapeutic proteins and could be used in continuous-culture bioreactor systems. Furthermore, it enabled rapid detection of administered microbes in intestinal and fecal samples.
Review
Chemistry, Applied
Jiayi Wu, Yuheng Zhang, Ling Ye, Chenglin Wang
Summary: Probiotic lactic acid bacteria EPS have potential anticancer effects by modulating tumor development through various mechanisms, and the future challenge lies in elucidating the precise structure-function relationship.
CARBOHYDRATE POLYMERS
(2021)
Review
Food Science & Technology
Ruchi Sharma, Samira Mokhtari, Seid Mahdi Jafari, Somesh Sharma
Summary: Consumers worldwide are increasingly focusing on the link between nutrition and health, with probiotics, prebiotics, and synbiotics playing a key role in functional foods. Barley is highlighted as a potential substrate for probiotic products due to its nutrient content and ability to support Lactobacilli in the gastrointestinal tract.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Food Science & Technology
Jagrani Minj, Priyanka Chandra, Catherine Paul, Rakesh Kumar Sharma
Summary: Lactic acid bacteria play crucial roles as starter cultures and probiotics in the fermentation and processing of dairy and food products, with various bio-functional properties that benefit human health. Their applications not only enhance the functionality of food products, but also have potential effects such as anti-inflammatory, antioxidant, and antimicrobial activities.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
Jianlong Li, Kaidi Hu, Lu Hu, Xiaoyan Hou, Qin Li, Aiping Liu, Shujuan Chen, Xiaolin Ao, Xinjie Hu, Li He, Huaqiao Tang, Daomei Huang, Yong Yang, Likou Zou, Shuliang Liu
Summary: 3-PBA, a major degradation intermediate of pyrethroids, poses a severe threat to the ecosystem and human health due to its widespread existence in the environment. This study evaluated the adsorption capacity of L. plantarum RS20 towards 3-PBA and found that strain RS20 could be employed as a biological detoxification agent for humans and animals by eliminating 3-PBA from foods, feeds, and the digestive tract.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Food Science & Technology
Dharmendra Kumar, Milan Kumar Lal, Som Dutt, Pinky Raigond, Sushil Sudhakar Changan, Rahul Kumar Tiwari, Kumar Nishant Chourasia, Vikas Mangal, Brajesh Singh
Summary: The current trend of health-conscious consumers and healthy food habits has led researchers to explore the development of food products with synbiotic benefits. This review article explores the alternative sources of probiotics and highlights various methods for making non-dairy synbiotics based on dietary fibers.
MOLECULAR NUTRITION & FOOD RESEARCH
(2022)
Article
Biotechnology & Applied Microbiology
Noeli Sirini, Paula Loyeau, Maria Ruiz, Maria Stegmayer, Lorena Soto, Maria Werning, Laureano Frizzo, Vanesa Ordonez, Juana Fernandez-Lopez, Marcelo Rosmini
Summary: The viability of microencapsulated and unencapsulated Lactiplantibacillus plantarum BFL and their effects on the microbiological and physicochemical parameters of fermented sausages were studied in this research. The results showed that the inoculated sausages had lower pH values and potential pathogenic microorganism counts. Encapsulated L. plantarum BFL had better viability during storage compared to its unencapsulated state. In addition, L. plantarum BFL exhibited an antioxidant effect at 20 degrees C towards the end of storage. Overall, L. plantarum BFL could be used as a biocontroller in the meat industry due to its high viability rates.
FERMENTATION-BASEL
(2022)
Article
Immunology
Diogo Contente, Patricia Diaz-Rosales, Javier Feito, Lara Diaz-Formoso, Felix Docando, Rocio Simon, Juan Borrero, Pablo E. Hernandez, Patricia Poeta, Estefania Munoz-Atienza, Luis M. Cintas, Carolina Tafalla
Summary: Lactic Acid Bacteria (LAB) are frequently used as probiotics in aquaculture and have been shown to positively affect the growth, survival rate, and immunological status of fish. LAB produce antimicrobial peptides called bacteriocins, which have been well-studied for their antimicrobial properties. However, the direct immunomodulatory effects of bacteriocins in fish have not been extensively explored. In this study, the immunomodulatory effects of different bacteriocin-producing LAB strains were compared, and it was found that these strains had varying effects on immune functions, with nisin Z being the most potent immunomodulator.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Seon-Joo Park, Anshul Sharma, Hae-Jeung Lee
Summary: Overweight and obesity are global public health concerns that are increasing rapidly. Probiotics have been shown to have benefits against obesity, and postbiotics, which are bacteria-free extracts and nonviable microorganisms, are being favored over regular probiotics. This review gathers comprehensive data on the ability of postbiotics to combat obesity and discusses their anti-obesity effects in cellular, animal, and clinical studies, suggesting that postbiotics could be a promising dietary intervention for obesity prevention and management.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Food Science & Technology
Soyoung Park, Kandasamy Saravanakumar, Anbazhagan Sathiyaseelan, SeonJu Park, Xiaowen Hu, Myeong-Hyeon Wang
Summary: The present study isolated and identified five lactic acid bacteria from Korean kimchi, with Weissella cibaria producing a high level of exopolysaccharide (EPS) compared to other isolates. The EPS from W. cibaria was found to be composed of glucose and galactose, linked through specific monosaccharides. It exhibited strong antioxidant activity and biocompatibility, making it a promising candidate for biomedical applications.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Multidisciplinary Sciences
Ronaldo Rwubuzizi, Hamin Kim, Wilhelm Heinrich Holzapfel, Svetoslav Dimitrov Todorov
Summary: The role of lactic acid bacteria (LAB) as probiotics in promoting human or veterinary health has attracted increasing interest. Screening approaches have been used to identify LAB strains that meet minimal requirements for safety and functionality, including natural antioxidant properties. In this study, several in vitro antioxidant assays were conducted to evaluate the antioxidant properties of different LAB strains, and some showed promising results that could potentially be applied as natural antioxidants in fermented food products.
Article
Agronomy
Mihaela Dumitru, Nicoleta Aurelia Lefter, Mihaela Habeanu, Georgeta Ciurescu, Dan C. Vodnar, Simon Elemer, Ionut Sorescu, Sergiu Emil Georgescu, Andreea Dudu
Summary: Fourteen lactic acid bacteria (LAB) strains were isolated from the intestinal tract and feces of piglets, and only 12 strains were confirmed as Limosilactobacillus fermentum, Lactobacillus acidophilus, and Lactiplantibacillus plantarum. Two strains, L. acidophilus IBNA 76 and L. plantarum IBNA 84, showed high survival rates under low pH and bile salts conditions. They also exhibited resistance to multiple antibiotics. After encapsulation using the spray-drying technique, the probiotic viability decreased but still remained promising. These findings suggest that L. acidophilus IBNA 76 and L. plantarum IBNA 84 could be considered as probiotic candidates for piglet nutrition.
Article
Biotechnology & Applied Microbiology
Buket Kunduhoglu, Seda Hacioglu
Summary: This study explored the gluten hydrolysis ability and probiotic potential of Lact. brevis KT16-2, which showed promising results in terms of surviving in adverse conditions, producing antimicrobial peptides, and exhibiting high antioxidant activity.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2021)
Article
Fisheries
Huiyu Zhang, Qiwen Zhang, Yan Li, Zhenjiang Zech Xu, Xiaochang Huang
Summary: This study aimed to isolate potential probiotics from freshwater fish and evaluate their effects on the growth, immune response, and disease resistance of juvenile zebrafish. Three strains (Leuconostoc mesenteroides GL-5, Weissella hellenica GJ-1, and Pediococcus claussenii GJ-3) were identified with antagonistic activity against fish pathogens, high bile salt tolerance, and good hydrophobicity. Feeding zebrafish with these probiotics significantly promoted their growth and improved their immune response and disease resistance.
AQUACULTURE INTERNATIONAL
(2023)
Article
Oncology
Katarzyna Garbacz
Summary: Lactic acid bacteria (LAB), naturally occurring in fermented food products and used as probiotics, have bioactive compounds with potential anticancer activity. Research has shown that these compounds can inhibit tumor growth through various mechanisms and have immunomodulatory effects. LAB has promising clinical applications in anticancer therapy.
SEMINARS IN CANCER BIOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Olga A. Nikiforova, Sergey Klykov, Anna Volski, Leon M. T. Dicks, Michael L. Chikindas
ANNALS OF MICROBIOLOGY
(2016)
Article
Biotechnology & Applied Microbiology
Winschau F. van Zyl, Shelly M. Deane, Leon M. T. Dicks
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2015)
Article
Biotechnology & Applied Microbiology
Akihito Endo, Yasuhiro Tanizawa, Naoto Tanaka, Shintaro Maeno, Himanshu Kumar, Yuh Shiwa, Sanae Okada, Hirofumi Yoshikawa, Leon Dicks, Junichi Nakagawa, Masanori Arita
Article
Microbiology
Jayesh J. Ahire, Deon P. Neveling, Leon M. T. Dicks
CURRENT MICROBIOLOGY
(2015)
Article
Biotechnology & Applied Microbiology
Martin B. Bezuidenhout, Anton D. van Staden, Gert A. Oosthuizen, Dimitar M. Dimitrov, Leon M. T. Dicks
BIOMED RESEARCH INTERNATIONAL
(2015)
Article
Biotechnology & Applied Microbiology
Basit Yousuf, Jayesh J. Ahire, Leon M. T. Dicks
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2016)
Article
Biotechnology & Applied Microbiology
Leon M. T. Dicks, Marlie Botha, Ben Loos, Carine Smith
ANNALS OF MICROBIOLOGY
(2015)
Article
Multidisciplinary Sciences
Jayesh J. Ahire, Deon P. Neveling, Melanie Hattingh, Leon M. T. Dicks
Article
Biotechnology & Applied Microbiology
Jayesh J. Ahire, Leon M. T. Dicks
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2015)
Review
Microbiology
Leon M. T. Dicks
Summary: The human gut contains almost 3000 microbial species, primarily bacteria, which produce quorum sensing molecules that influence the gut microbiome and communicate with the host. These molecules have a significant effect on our physiological and mental health.
Review
Microbiology
Leon M. T. Dicks, Wian Vermeulen
Summary: Cancer is a major cause of death and illness globally, with various types of cancer showing an increasing trend worldwide. Treatment methods for cancer vary, but commonly include surgery, radiotherapy, and chemotherapy. Recent research has focused on the role of bacteria and their metabolites in cancer treatment.
Review
Microbiology
Leon M. T. Dicks
Summary: Gut bacteria communicate with the central nervous system through the production of specific metabolic compounds and the transmission of signals via the vagus nerve. The gut microbiota also influences the central nervous system by controlling the regulation and development of gut neurons. Additionally, the metabolites produced by gut bacteria interact with intestinal epithelial cells and neurons, affecting the synthesis and degradation of neurotransmitters.
Article
Microbiology
Francesco Salini, Lucilla Iacumin, Giuseppe Comi, Leon M. T. Dicks
Summary: Bacteriocins are proteinaceous toxins produced by bacteria and archaea, which have antimicrobial activity against closely related species. In this study, a new bacteriocin gene cluster was discovered, providing insights into understanding the production mechanism of thermophilin 13.
Review
Microbiology
Leon M. T. Dicks
Summary: This article summarizes factors affecting the colonization of C. difficile and the pathogenicity of toxins TcdA and TcdB, and evaluates different approaches for the treatment of CDI.
Review
Gastroenterology & Hepatology
Winschau F. van Zyl, Shelly M. Deane, Leon M. T. Dicks