Article
Infectious Diseases
Gleice C. Leite, Lauro Perdiga, Roberta C. Ruedas Martins, Camila Rizek, Anna Sara Levin, Silvia F. Costa
Summary: This study evaluated fosfomycin susceptibility in multi-resistant A. baumannii isolates and characterized fosfomycin resistance mechanisms. The analysis revealed different pathways that may contribute to the intrinsic fosfomycin-resistance of A. baumannii.
INFECTION GENETICS AND EVOLUTION
(2021)
Article
Microbiology
Jacinda C. Abdul-Mutakabbir, Logan Nguyen, Philip T. Maassen, Kyle C. Stamper, Razieh Kebriaei, Keith S. Kaye, Mariana Castanheira, Michael J. Rybak
Summary: Cefiderocol, a novel siderophore cephalosporin, shows potent activity against multidrug-resistant Acinetobacter baumannii, with lower MIC values compared to other Gram-negative agents. Studies indicate synergistic effects when combined with other antibiotics, and beta-lactamase inhibitors increase susceptibility to CFDC in MDR A. baumannii isolates.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2021)
Article
Pediatrics
Capan Konca, Mehmet Tekin, Mehmet Geyik
Summary: The study investigated the antimicrobial resistance patterns of multidrug-resistant Acinetobacter baumannii in pediatric intensive care unit patients. Results showed that many previously effective drugs have lost their effectiveness against MDRAB, with colistin remaining as the only effective drug. New drugs and treatment protocols are urgently needed to combat MDRAB.
INDIAN JOURNAL OF PEDIATRICS
(2021)
Article
Microbiology
Yi Huang, Md Roushan Ali, Wei Li, Wanying Wang, Yuanyuan Dai, Huaiwei Lu, Zhien He, Yujie Li, Baolin Sun
Summary: This study focused on Acinetobacter baumannii, a major health threat, and specifically investigated the ST369 strain prevalent in China. The researchers identified potential mutations that could impact bacterial virulence and resistance, providing a foundation for further research on clinical isolates harboring similar mutations.
Article
Chemistry, Multidisciplinary
Bei Ran, Yuyu Yuan, Wenxi Xia, Mingle Li, Qichao Yao, Zuokai Wang, Lili Wang, Xiaoyu Li, Yongping Xu, Xiaojun Peng
Summary: This study introduces a unique cationic photosensitizer (NB) and bacteriophage (ABP)-based photodynamic antimicrobial agent (APNB) for precise bacterial eradication and biofilm ablation. The APNB demonstrates excellent reactive oxygen species (ROS)-production ability and specific binding to pathogenic microorganisms provided by bacteriophages. It shows potential for fighting against multidrug-resistant bacteria and biofilm ablation in practice.
Article
Chemistry, Medicinal
E. H. T. Thulshan Jayathilaka, Dinusha C. Rajapaksha, Chamilani Nikapitiya, Joeun Lee, Mahanama De Zoysa, Ilson Whang
Summary: Octoprohibitin, a synthetic antimicrobial peptide derived from the prohibitin-2 gene of Octopus minor, showed significant activity against multidrug resistant Acinetobacter baumannii, inhibiting both bacterial growth and biofilm formation.
Article
Biology
Tatjana Kirtikliene, Aiste Mierauskaite, Ilona Razmiene, Nomeda Kuisiene
Summary: The study analyzed multidrug-resistant Acinetobacter spp. isolates from human bloodstream infections in 14 healthcare institutions in Lithuania during 2014, 2016, and 2018. The results indicated potential relatedness of different Acinetobacter spp. isolates and circulation of resistance genes or profiles in different years of the study.
Article
Infectious Diseases
Suhaila A. Al-Sheboul, Salam Z. Al-Moghrabi, Yasemin Shboul, Farah Atawneh, Ahmed H. Sharie, Laila F. Nimri
Summary: This study aimed to determine the presence and distribution of bla(OXA) genes among multidrug-resistant A. baumannii isolated from ICU patients in Jordanian hospitals. The results showed a high prevalence of multidrug-resistant strains with ESBL phenotype. Identification of ESBL genes is crucial for monitoring their transmission in hospitals.
Review
Medicine, General & Internal
Guido Granata, Fabrizio Taglietti, Francesco Schiavone, Nicola Petrosillo
Summary: This study assessed the efficacy and safety of a novel antibiotic, durlobactam, in the treatment of multidrug-resistant A. baumannii infections. Sixteen studies met the inclusion criteria, and it was found that durlobactam is effective when used in combination with sulbactam against A. baumannii. Further clinical trials are needed to confirm the potential of this combination therapy for treating infections caused by multidrug-resistant A. baumannii.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Biotechnology & Applied Microbiology
Elnaz Abbasi, Alex van Belkum, Ehsanollah Ghaznavi-Rad
Summary: The frequency of infections caused by wild-type A. baumannii, multidrug-resistant (MDR) or XDR A. baumannii, and CRAB were assessed in central Iran. Different antibiotic resistance genes were detected in the genomes of infectious A. baumannii strains.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2023)
Review
Immunology
Ayman Elbehiry, Eman Marzouk, Ihab Moussa, Yazeed Mushayt, Ahmad Abdullah Algarni, Osama Ali Alrashed, Khalid Saad Alghamdi, Naif Ahmed Almutairi, Sulaiman Abdulaziz Anagreyyah, Anwar Alzahrani, Abdulaziz M. Almuzaini, Feras Alzaben, Meshal Abdullah Alotaibi, Suha Abdulaziz Anjiria, Akram Abu-Okail, Adil Abalkhail
Summary: Healthcare providers worldwide are increasingly concerned about the prevalence of multidrug-resistant Acinetobacter baumannii (A. baumannii). This bacterial pathogen is responsible for some of the most severe hospital-acquired infections, particularly in intensive care units (ICUs). The rise in multidrug-resistant A. baumannii has been attributed to the overuse of antimicrobial drugs and inadequate infection control measures. Infections caused by this pathogen are associated with prolonged hospitalization and ICU stays, leading to increased morbidity and mortality.
Article
Infectious Diseases
Jia-Ling Yang, Chia-Jui Yang, Yu-Chung Chuang, Wang-Huei Sheng, Yee-Chun Chen, Shan-Chwen Chang
Summary: This study evaluated the susceptibility of carbapenem-resistant Acinetobacter baumannii (CRAB) clinical strains to minocycline, and found a significant correlation between tetB carriage and minocycline susceptibility in CRAB.
INFECTION AND DRUG RESISTANCE
(2022)
Review
Medicine, General & Internal
Flora Cruz-Lopez, Adrian Martinez-Melendez, Licet Villarreal-Trevino, Rayo Morfin-Otero, Hector Maldonado-Garza, Elvira Garza-Gonzalez
Summary: This review examines the contamination of CRAB on corporal surfaces of patients and healthcare workers, as well as environmental sites in healthcare-related settings. It summarizes the published data on potential reservoirs, contamination frequency, resistance mechanisms, and measures for eliminating CRAB from hospital surfaces.
AMERICAN JOURNAL OF THE MEDICAL SCIENCES
(2022)
Article
Microbiology
Irina Gheorghe-Barbu, Viorica Maria Corbu, Corneliu Ovidiu Vrancianu, Ioana Cristina Marinas, Marcela Popa, Andreea Stefania Dumbrava, Mihai Nita-Lazar, Ionut Pecete, Andrei Alexandru Muntean, Mircea Ioan Popa, Liliana Marinescu, Denisa Ficai, Anton Ficai, Ilda Czobor Barbu
Summary: This study aims to demonstrate the effectiveness of silver nanoparticles on multidrug-resistant Acinetobacter baumannii strains isolated from hospitals and water sources. The results show that silver nanoparticles have inhibitory effects on bacterial growth, biofilm formation, and the production of soluble virulence factors. This is the first description of an antibacterial agent against MDR AB strains in Romania's hospitals and anthropically polluted water.
Review
Microbiology
Sunil Kumar, Razique Anwer, Arezki Azzi
Summary: Acinetobacter baumannii is a deadly opportunist pathogen in hospital-acquired infections, with limited treatment options due to the emergence of multidrug-resistant strains. Understanding the virulence factors of A. baumannii is crucial for overcoming this threat.
Article
Veterinary Sciences
Prapas Patchanee, Kankanok Tansiricharoenkul, Tunyamai Buawiratlert, Anuwat Wiratsudakul, Kittipat Angchokchatchawal, Panuwat Yamsakul, Terdsak Yano, Phacharaporn Boonkhot, Suvichai Rojanasatien, Pakpoom Tadee
PREVENTIVE VETERINARY MEDICINE
(2016)
Article
Food Science & Technology
Prapas Patchanee, Thanaporn Eiamsam-ang, Juntakarn Vanaseang, Phacharaporn Boonkhot, Pakpoom Tadee
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2017)
Article
Food Science & Technology
Mongkol Kaewsutas, Ariya Sarikaphuti, Thamthiwat Nararatwanchai, Phakkharawat Sittiprapaporn, Prapas Patchanee
JOURNAL OF FUNCTIONAL FOODS
(2017)
Article
Genetics & Heredity
Vijaya Bharathi Srinivasan, Mahavinod Angrasan, Neha Chandel, Govindan Rajamohan
FUNCTIONAL & INTEGRATIVE GENOMICS
(2018)
Article
Biotechnology & Applied Microbiology
Vijaya Bharathi Srinivasan, Govindan Rajamohan
Article
Microbiology
Vijaya Bharathi Srinivasan, Vasanth Vaidyanathan, Govindan Rajamohan
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2015)
Article
Multidisciplinary Sciences
Pakpoom Tadee, Phacharaporn Boonkhot, Srirat Pornruangwong, Prapas Patchanee
Article
Multidisciplinary Sciences
Vijaya Bharathi Srinivasan, Manjunath Venkataramaiah, Amitabha Mondal, Govindan Rajamohan
Article
Multidisciplinary Sciences
Amitabha Mondal, Manjunath Venkataramaiah, Govindan Rajamohan, Vijaya Bharathi Srinivasan
Article
Public, Environmental & Occupational Health
S. Pornsukarom, P. Patchanee, M. Erdman, P. F. Cray, T. Wittum, J. Lee, W. A. Gebreyes
ZOONOSES AND PUBLIC HEALTH
(2015)
Article
Immunology
Ellen J. McCleery, Prapas Patchanee, Pornsawan Pongsopawijit, Sasisophin Chailangkarn, Saruda Tiwananthagorn, Papaspong Jongchansittoe, Anchalee Dantrakool, Nimit Morakote, Hnin Phyu, Patricia P. Wilkins, John C. Noh, Christina Phares, Seth O'Neal, Charsey Cole Porse
EMERGING INFECTIOUS DISEASES
(2015)
Article
Public, Environmental & Occupational Health
Prapas Patchanee, Phacharaporn Boonkhot, Nattinee Kittiwan, Pakpoom Tadee, Suwit Chotinun
SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH
(2015)
Article
Veterinary Sciences
Phacharaporn Boonkhot, Pakpoom Tadee, Prapas Patchanee
ACTA SCIENTIAE VETERINARIAE
(2015)
Article
Veterinary Sciences
Phacharaporn Boonkhot, Pakpoom Tadee, Panuwat Yamsakul, Chairoj Pocharoen, Nipa Chokesajjawatee, Prapas Patchanee
JAPANESE JOURNAL OF VETERINARY RESEARCH
(2015)
Article
Public, Environmental & Occupational Health
Suwit Chotinun, Suvichai Rojanasthien, Fred Unger, Pakpoom Tadee, Prapas Patchanee
SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH
(2014)