Antiretroviral Solid Drug Nanoparticles with Enhanced Oral Bioavailability: Production, Characterization, and In Vitro-In Vivo Correlation

An Insight into Thermodynamic Relationship Between Polymorphic Forms of Efavirenz

(2016) Renu Chadha et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Prediction of drug-drug Interactions Between Various Antidepressants and Efavirenz or Boosted Protease Inhibitors Using a Physiologically Based Pharmacokinetic Modelling Approach

(2013) Marco Siccardi et al.   CLINICAL PHARMACOKINETICS

Mediation of in Vitro Cytochrome P450 Activity by Common Pharmaceutical Excipients

(2013) Philip Martin et al.   MOLECULAR PHARMACEUTICS

Drug Synergy of Tenofovir and Nanoparticle-Based Antiretrovirals for HIV Prophylaxis

(2013) Thanyanan Chaowanachan et al.   PLoS One

Multicomponent Organic Nanoparticles for Fluorescence Studies in Biological Systems

(2012) Tom O. McDonald et al.   ADVANCED FUNCTIONAL MATERIALS

Development and evaluation of a thermosensitive vaginal gel containing raltegravir+efavirenz loaded nanoparticles for HIV prophylaxis

(2012) Abhijit A. Date et al.   ANTIVIRAL RESEARCH

Pharmacokinetic and Pharmacodynamic Analysis of Efavirenz Dose Reduction Using an In Vitro–In Vivo Extrapolation Model

(2012) M Siccardi et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Poly(ɛ-caprolactone), Eudragit® RS 100 and poly(ɛ-caprolactone)/Eudragit® RS 100 blend submicron particles for the sustained release of the antiretroviral efavirenz

(2012) Katia P. Seremeta et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

An improved model to predict physiologically based model parameters and their inter-individual variability from anthropometry

(2012) Sieto Bosgra et al.   CRITICAL REVIEWS IN TOXICOLOGY

Mononuclear phagocyte intercellular crosstalk facilitates transmission of cell-targeted nanoformulated antiretroviral drugs to human brain endothelial cells

(2012) Georgette Kanmogne et al.   International Journal of Nanomedicine

Pharmacodynamic and Antiretroviral Activities of Combination Nanoformulated Antiretrovirals in HIV-1–Infected Human Peripheral Blood Lymphocyte–Reconstituted Mice

(2012) Upal Roy et al.   JOURNAL OF INFECTIOUS DISEASES

Dose reduction of antiretrovirals: a feasible and testable approach to expand HIV treatment in developing countries

(2012) Sandro Vento et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Efavirenz is a substrate and in turn modulates the expression of the efflux transporter ABCG2/BCRP in the gastrointestinal tract of the rat

(2011) Roxana N. Peroni et al.   BIOCHEMICAL PHARMACOLOGY

Are there differences in the catalytic activity per unit enzyme of recombinantly expressed and human liver microsomal cytochrome P450 2C9? A systematic investigation into inter-system extrapolation factors

(2011) H. K. Crewe et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Polymer therapeutics as nanomedicines: new perspectives

(2011) Ruth Duncan   CURRENT OPINION IN BIOTECHNOLOGY

Drug delivery systems for differential release in combination therapy

(2011) Hongbin Zhang et al.   Expert Opinion on Drug Delivery

Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival-promoting autophagy

(2011) Nadezda Apostolova et al.   HEPATOLOGY

Nanosuspensions of poorly soluble drugs: Preparation and development by wet milling

(2011) Peng Liu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

UPLC–MS/MS quantification of nanoformulated ritonavir, indinavir, atazanavir, and efavirenz in mouse serum and tissues

(2011) Jiangeng Huang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Nanomedicine(s) under the Microscope

(2011) Ruth Duncan et al.   MOLECULAR PHARMACEUTICS

Synergistic encapsulation of the anti-HIV agent efavirenz within mixed poloxamine/poloxamer polymeric micelles

(2011) Diego A. Chiappetta et al.   Nanomedicine-Nanotechnology Biology and Medicine

Inaugural open issue

(2011) Kamalesh K Sirkar   Current Opinion in Chemical Engineering

Pharmacokinetics and Disposition of Rilpivirine (TMC278) Nanosuspension as a Long-Acting Injectable Antiretroviral Formulation

(2010) G. van 't Klooster et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Oral pharmacokinetics of the anti-HIV efavirenz encapsulated within polymeric micelles

(2010) Diego A. Chiappetta et al.   BIOMATERIALS

N-alkylation of poloxamines modulates micellar assembly and encapsulation and release of the antiretroviral efavirenz

(2010) Diego A. Chiappetta et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Polymeric micelles for oral drug delivery

(2010) Geneviève Gaucher et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Drug delivery and nanoparticles: Applications and hazards

(2010) de Jong   International Journal of Nanomedicine

Antiretroviral release from poly(DL-lactide-co-glycolide) nanoparticles in mice

(2010) C. J. Destache et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages

(2010) Ari S. Nowacek et al.   JOURNAL OF CONTROLLED RELEASE

Nanoformulated Antiretroviral Drug Combinations Extend Drug Release and Antiretroviral Responses in HIV-1-Infected Macrophages: Implications for NeuroAIDS Therapeutics

(2010) Ari S. Nowacek et al.   Journal of Neuroimmune Pharmacology

Dendrimers as therapeutic agents: a systematic review

(2010) Virendra Gajbhiye et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Pharmaceutical nanocrystals by nanomilling: critical process parameters, particle fracturing and stabilization methods

(2010) Leena Peltonen et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Advances in polymeric micelles for drug delivery and tumor targeting

(2010) Uttam Kedar et al.   Nanomedicine-Nanotechnology Biology and Medicine

Pharmacotoxicology of monocyte-macrophage nanoformulated antiretroviral drug uptake and carriage

(2010) Rafael F. Bressani et al.   Nanotoxicology

Combination antiretroviral drugs in PLGA nanoparticle for HIV-1

(2009) Christopher J Destache et al.   BMC INFECTIOUS DISEASES

Development of a long-acting injectable formulation with nanoparticles of rilpivirine (TMC278) for HIV treatment

(2009) Lieven Baert et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Efavirenz: a decade of clinical experience in the treatment of HIV

(2009) F. Maggiolo   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

NanoART synthesis, characterization, uptake, release and toxicology for human monocyte–macrophage drug delivery

(2009) Ari S Nowacek et al.   Nanomedicine

Efavirenz-loaded polymeric micelles for pediatric anti-HIV pharmacotherapy with significantly higher oral bioavailability

(2009) Diego A Chiappetta et al.   Nanomedicine

When to Start Antiretroviral Therapy — Ready When You Are?

(2009) Paul E. Sax et al.   NEW ENGLAND JOURNAL OF MEDICINE

Self-assembling materials for therapeutic delivery

(2008) Monica C. Branco et al.   Acta Biomaterialia

Characterization of the inhibition of breast cancer resistance protein-mediated efflux of mitoxantrone by pharmaceutical excipients

(2008) Tetsuo Yamagata et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients

(2008) C. Wyen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Polymeric micelles in oral chemotherapy

(2008) Lev Bromberg   JOURNAL OF CONTROLLED RELEASE

Formation and enhanced biocidal activity of water-dispersable organic nanoparticles

(2008) Haifei Zhang et al.   Nature Nanotechnology

Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells

(2007) P Martin et al.   BRITISH JOURNAL OF PHARMACOLOGY