A novel homozygous mutation in GAD1 gene described in a schizophrenic patient impairs activity and dimerization of GAD67 enzyme

Psychiatric Genomics: An Update and an Agenda

(2018) Patrick F. Sullivan et al.   AMERICAN JOURNAL OF PSYCHIATRY

Exome sequencing in schizophrenic patients with high levels of homozygosity identifies novel and extremely rare mutations in the GABA/glutamatergic pathways

(2017) Edoardo Giacopuzzi et al.   PLoS One

Polygenic Risk Score associated with specific symptom dimensions in first-episode psychosis

(2017) Sarojini M. Sengupta et al.   SCHIZOPHRENIA RESEARCH

Comprehensive association analysis of 27 genes from the GABAergic system in Japanese individuals affected with schizophrenia

(2017) Shabeesh Balan et al.   SCHIZOPHRENIA RESEARCH

GABAergic Mechanisms in Schizophrenia: Linking Postmortem and In Vivo Studies

(2017) Jeroen C. de Jonge et al.   Frontiers in Psychiatry

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

(2016) Tarjinder Singh et al.   NATURE NEUROSCIENCE

The GRM7 gene, early response to risperidone and schizophrenia: a genome-wide association study and a confirmatory pharmacogenetic analysis

(2016) E Sacchetti et al.   PHARMACOGENOMICS JOURNAL

No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study

(2016) Emma C. Johnson et al.   PLoS Genetics

Investigation of Recessive Effects in Schizophrenia Using Next-Generation Exome Sequence Data

(2015) David Curtis   ANNALS OF HUMAN GENETICS

Genetic Risk for Schizophrenia: Convergence on Synaptic Pathways Involved in Plasticity

(2015) Jeremy Hall et al.   BIOLOGICAL PSYCHIATRY

Novel Findings from CNVs Implicate Inhibitory and Excitatory Signaling Complexes in Schizophrenia

(2015) Andrew J. Pocklington et al.   NEURON

Glutamate Decarboxylase 67 Deficiency in a Subset of GABAergic Neurons Induces Schizophrenia-Related Phenotypes

(2015) Kazuyuki Fujihara et al.   NEUROPSYCHOPHARMACOLOGY

Transcriptional regulation of GAD1 GABA synthesis gene in the prefrontal cortex of subjects with schizophrenia

(2015) Amanda C. Mitchell et al.   SCHIZOPHRENIA RESEARCH

Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia

(2015) E Rees et al.   Translational Psychiatry

Compartmentalization of GABA Synthesis by GAD67 Differs between Pancreatic Beta Cells and Neurons

(2015) Jamil Kanaani et al.   PLoS One

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Runs of Homozygosity Implicate Autozygosity as a Schizophrenia Risk Factor

(2014) Matthew C. Keller et al.   PLoS Genetics

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

(2013) Stephan Ripke et al.   NATURE GENETICS

Exome Sequencing Followed by Large-Scale Genotyping Suggests a Limited Role for Moderately Rare Risk Factors of Strong Effect in Schizophrenia

(2012) Anna C. Need et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

(2012) S Hong Lee et al.   NATURE GENETICS

The Dynamics of DNA Methylation in Schizophrenia and Related Psychiatric Disorders

(2012) Dennis R Grayson et al.   NEUROPSYCHOPHARMACOLOGY

Expression of GABA Signaling Molecules KCC2, NKCC1, and GAD1 in Cortical Development and Schizophrenia

(2011) T. M. Hyde et al.   JOURNAL OF NEUROSCIENCE

Genome-wide association study identifies five new schizophrenia loci

(2011)   NATURE GENETICS

Disease- and age-related changes in histone acetylation at gene promoters in psychiatric disorders

(2011) B Tang et al.   Translational Psychiatry

Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces

(2010) Hanka Venselaar et al.   BMC BIOINFORMATICS

Two distinct mechanisms target GAD67 to vesicular pathways and presynaptic clusters

(2010) Jamil Kanaani et al.   JOURNAL OF CELL BIOLOGY

GABA Concentration Is Reduced in Visual Cortex in Schizophrenia and Correlates with Orientation-Specific Surround Suppression

(2010) J. H. Yoon et al.   JOURNAL OF NEUROSCIENCE

New Copy Number Variations in Schizophrenia

(2010) Chiara Magri et al.   PLoS One

The role of copy number variation in schizophrenia

(2009) George Kirov   Expert Review of Neurotherapeutics

Adult and Embryonic GAD Transcripts Are Spatiotemporally Regulated during Postnatal Development in the Rat Brain

(2009) Anke Popp et al.   PLoS One

The Neurodevelopmental Hypothesis of Schizophrenia, Revisited

(2009) S. H. Fatemi et al.   SCHIZOPHRENIA BULLETIN

A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia

(2009) Anna C. Need et al.   PLoS Genetics