Article
Marine & Freshwater Biology
Mahdi Banaee, Javad Faraji, Mohammad Amini, Cristiana Roberta Multisanti, Caterina Faggio
Summary: The combination of enrofloxacin (ENR) and microplastics (MPs) increases their toxicity and negatively affects fish health.
AQUATIC TOXICOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Yu Jin, Yi Zhou, Wenfeng Deng, Yuchen Wang, Richard J. Lee, Yanna Liu, Nahel Elias, Yangcheng Hu, Min-Hua Luo, Rumin Liu, Bowen Guan, Jian Geng, Jian Xu, Junfeng Ma, Jiapeng Zhou, Na Liu, Michael L. Blute, Robert B. Colvin, Chin-Lee Wu, Yun Miao
Summary: Chronic BK polyomavirus (BKPyV) infection is considered a potential oncogenic factor for urothelial carcinoma (UC) in renal transplant recipients. Integration sites between human and BKPyV genomes were enriched with microhomologies, and viral insertional integration led to fusion sequences of 75 human genes, with 15 genes showing statistical association with UC based on expression analysis. These findings suggest a potential mechanism of viral-driven carcinogenesis in BKPyV-related UC.
Article
Pediatrics
Lisa Biswas, Noreen Crain, Michael C. Spaeder, Robert J. Gomez, Meghan Starolis, Melinda D. Poulter, Steven L. Zeichner
Summary: Multisystem inflammatory syndrome in children (MIS-C) is a serious late complication of COVID-19 with unknown pathogenesis and immune activation. Research has shown a potential association between MIS-C and the presence of HHV-6, suggesting a role in the pathogenesis of the disease.
Review
Biochemistry & Molecular Biology
Carmen Beatrice Dogaru, Corina Muscurel, Carmen Duta, Irina Stoian
Summary: This review discusses the identity and functions of several less-known selenoproteins, which play important roles in various physiological and pathogenic processes, including antioxidant defense, anti-inflammation, anti-apoptosis, and immune and inflammatory response.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Camila Guimaraes Torquetti, Thaynara Parente de Carvalho, Renata Maria Pereira de Freitas, Mariella Bontempo Freitas, Ana Tereza Bittencourt Guimaraes, Benito -Blanco
Summary: This study evaluated the health condition of bats from different food guilds captured in two areas with different land use profiles in Brazil and compared data on the oxidant-antioxidant balance and histopathological changes. Despite differences in land use and occupation, bats showed similar responses, but the trophic guilds were affected differently.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Biochemistry & Molecular Biology
Qinqin Cui, Hongyun Bi, Zhanyun Lv, Qigui Wu, Jianfeng Hua, Bokai Gu, Chanjuan Huo, Mingmin Tang, Yanqin Chen, Chongjiu Chen, Sihan Chen, Xinrui Zhang, Zhangrui Wu, Zhengkai Lao, Nengyin Sheng, Chengyong Shen, Yongdeng Zhang, Zhi-Ying Wu, Zhigang Jin, Peiguo Yang, Huaqing Liu, Jinsong Li, Ge Bai
Summary: Complex diseases often involve the interplay between genetic and environmental factors. Charcot-Marie-Tooth type 2 neuropathies (CMT2) are a group of genetically heterogeneous disorders, in which similar peripheral neuropathology is caused by various mutated genes. This study reveals a stress-dependent molecular link across diverse CMT2 mutants and provides a conceptual framework for understanding genetic heterogeneity in light of environmental stress.
Article
Chemistry, Multidisciplinary
Silvia Krizanac, Natalija Topic Popovic, Josip Barisic, Blanka Beer-Ljubic, Maro Bujak, Sanja Babic, Krunoslav Bojanic, Rozelindra Coz-Rakovac, Daniel Matulic, Ivancica Strunjak-Perovic
Summary: This study aimed to compare the organismal responses of farmed and wild-caught turbot through analyzing biochemical plasma parameters, leukocyte profile, histological tissue profile, and gene expression. The results showed significant differences in various parameters between the two populations, including higher levels of certain biochemical parameters in the farmed population and increased gene expression in the wild-caught turbot. The wild-caught turbot were also found to be infested with two parasites.
APPLIED SCIENCES-BASEL
(2022)
Review
Plant Sciences
Sameer H. Qari, Muhammad Umair Hassan, Muhammad Umer Chattha, Athar Mahmood, Maria Naqve, Muhammad Nawaz, Lorenzo Barbanti, Maryam A. Alahdal, Maha Aljabri
Summary: Cold stress is a major constraint for plant growth and development. The application of melatonin, a critical bio-stimulant, has been found to improve plant performance under cold stress by maintaining membrane integrity, water uptake, photosynthetic efficiency, and antioxidant activities.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Satish Kumar Sanwal, Parveen Kumar, Hari Kesh, Vijai Kishor Gupta, Arvind Kumar, Ashwani Kumar, Babu Lal Meena, Giuseppe Colla, Mariateresa Cardarelli, Pradeep Kumar
Summary: Salinity stress significantly reduces plant height, stem numbers, and tuber yield in potato varieties. Salt-tolerant genotypes exhibit better performance under salt stress due to a strong antioxidant defense system and osmotic adjustment, suggesting their potential for breeding new high-yielding, salt-tolerant lines. Specific physiological and biochemical traits were identified as predominant for tuber yield under salt stress, providing insights for further genetic and molecular studies on salt tolerance in potato.
Article
Environmental Sciences
F. Impellitteri, K. Yunko, V. Martyniuk, T. Matskiv, S. Lechachenko, V. Khoma, A. Mudra, G. Piccione, O. Stoliar, C. Faggio
Summary: This study aimed to investigate the impact of caffeine on marine mussels in combination with microplastics. The results showed that the combination of microplastics and caffeine had effects on the physiological indicators of mussels, while caffeine alone did not have a significant impact on oxidative stress indicators.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Biochemistry & Molecular Biology
Liang Liu, Wanying Zhang, Tanghao Liu, Yangfan Tan, Cheng Chen, Jun Zhao, Huan Geng, Chi Ma
Summary: This study investigated the effect and mechanism of alpha-ketoglutarate (alpha-KG) on osteoarthritis (OA). It was found that alpha-KG levels decreased in human OA cartilage and IL-1 beta-induced osteoarthritic chondrocytes. Moreover, alpha-KG supplementation alleviated the osteoarthritic phenotype by regulating mitophagy and oxidative stress, suggesting its potential as a therapeutic target for OA.
Article
Multidisciplinary Sciences
Mateusz Noszka, Agnieszka Strzalka, Jakub Muraszko, Rafal Kolenda, Chen Meng, Christina Ludwig, Kerstin Stingl, Anna Zawilak-Pawlik
Summary: This study presents a comprehensive investigation of the redox switch protein HP1021 regulon in the gastric human pathogen Helicobacter pylori. The findings suggest that HP1021 plays a crucial role in modulating the response to oxidative stress in H. pylori, controlling the transcription of numerous genes and influencing the expression of proteins involved in various pathways. Additionally, HP1021 is found to regulate competence and glucose consumption, impacting the energetic balance in the cell.
NATURE COMMUNICATIONS
(2023)
Article
Plant Sciences
Satish Kumar Sanwal, Hari Kesh, Arvind Kumar, Bhanu Kumar Dubey, Anil Khar, Youssef Rouphael, Pradeep Kumar
Summary: This study aimed to identify salt-tolerant onion genotypes by studying the physiological and biochemical mechanisms under salt stress. The results showed differences in growth and yield reduction among different onion varieties under salt stress. Salt-tolerant varieties exhibited higher physiological traits and better antioxidant capacity, while salt-sensitive varieties showed more membrane injury and higher salt accumulation.
Article
Plant Sciences
Fan Mo, Haibo Li, Yinghua Li, Xi Chen, Mingshuai Wang, Zhe Li, Ningcan Deng, Yue Yang, Xin Huang, Ran Zhang, Wenhe Deng
Summary: Red clover shows strong Ag absorption capacity and an accumulation response to reactive oxygen species, contributing to its tolerance to Ag stress. The molecular mechanisms involved in this tolerance include genes related to metal ion binding, hormone responses, calcium signaling, and protein ubiquitination, as well as pathways such as plant-pathogen interaction and ubiquitin mediated proteolysis. Several down-regulated genes indicate possible metabolic disturbance, while pivotal genes like ribosomal proteins and transcription factors play important roles in Ag tolerance of red clover.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Review
Biochemistry & Molecular Biology
Alice Au, Albaraa Mojadadi, Jia-Ying Shao, Gulfam Ahmad, Paul K. Witting
Summary: Dietary selenium intake is crucial for maintaining biological functions, and different chemical forms of selenium have varying health impacts. Recent studies have focused on the use of selenium nanoparticles, which show lower toxicity and higher bioavailability compared to traditional forms. These nanoparticles have shown promising effects on growth, reproduction, oxidative stress, and inflammation, making them potential candidates for agriculture and therapeutic applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Zoology
Roberta Bisconti, Claudio Carere, David Costantini, Anita Liparoto, Andrea Chiocchio, Daniele Canestrelli
Summary: Recent studies have shown that personality and locomotory performance traits are important for dispersal syndromes and can evolve during range expansions and colonization. However, little is known about the effects of island colonization on these traits and how they contribute to colonization. In this study, we investigated the contribution of island colonization triggered by postglacial range expansions to intraspecific variation in personality and locomotory performance traits in the Tyrrhenian tree frog. We found that individuals from the recently colonized island were bolder, while individuals from the main island showed higher jumping and stickiness performance.
Article
Agriculture, Dairy & Animal Science
Ulrike Jakop, Britta Hensel, Gabor A. Czirjak, Monike Quirino, Filip Schroter, Markus Jung, Martin Schulze
Summary: This study investigated the antimicrobial defense mechanism in stallion semen and found that all samples showed antimicrobial activity, which was stable. Lysozyme concentration was positively correlated with the ratio of apoptotic spermatozoa.
REPRODUCTION IN DOMESTIC ANIMALS
(2023)
Review
Biodiversity Conservation
B. G. Parker, M. Khanyari, H. Ambarli, B. Buuveibaatar, M. Kabir, G. Khanal, H. R. Mirzadeh, Y. Onon, M. S. Farhadinia
Summary: This study provides an overview of trophy hunting characteristics in Asia, including the number of countries with hunting programs, the target species, hunting areas, and permit prices. The findings reveal variations in these characteristics among countries, highlighting the need for further research on the ecological and socioeconomic impacts of trophy hunting. The study also emphasizes the importance of evaluating the contributions of trophy hunting to conservation efforts and the post-2020 Global Biodiversity Framework, as well as examining public perceptions of trophy hunting.
ANIMAL CONSERVATION
(2023)
Review
Immunology
Sharvan Sehrawat, Nikolaus Osterrieder, D. Scott Schmid, Barry T. Rouse
Summary: The success of mRNA vaccines in managing COVID-19 opens up the possibility of using this platform for other viral diseases in humans and animals, potentially leading to more effective vaccines. This article discusses the reasons behind the success of mRNA vaccines against COVID-19 and explores the potential application of mRNA vaccines in controlling other infections.
MICROBES AND INFECTION
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Byoung-Won Park, Young Woo Park, Bo Da Nam, Seong Soon Kwon
Article
Ecology
Martina Ferraguti, Sergio Magallanes, Jessica Jimenez-Penuela, Josue Martinez-de la Puente, Luz Garcia-Longoria, Jordi Figuerola, Jaime Muriel, Tamer Albayrak, Staffan Bensch, Camille Bonneaud, Rohan H. Clarke, Gabor A. Czirjak, Dimitar Dimitrov, Kathya Espinoza, John G. Ewen, Farah Ishtiaq, Wendy Flores-Saavedra, Laszlo Zsolt Garamszegi, Olof Hellgren, Dita Horakova, Kathryn P. Huyvaert, Henrik Jensen, Asta Krizanauskiene, Marcos R. Lima, Charlene Lujan-Vega, Eyofinn Magnussen, Lynn B. Martin, Kevin D. Matson, Anders Pape Moller, Pavel Munclinger, Vaidas Palinauskas, Peter L. Pap, Javier Perez-Tris, Swen C. Renner, Robert Ricklefs, Sergio Scebba, Ravinder N. M. Sehgal, Manuel Soler, Eszter Szoellosi, Gediminas Valkiunas, Helena Westerdahl, Pavel Zehtindjiev, Alfonso Marzal
Summary: This study investigated the ecological drivers affecting avian malaria parasite lineages in native and introduced house sparrows. The results showed that urbanization was positively related to parasite prevalence in both native and introduced populations, with higher infection in areas with intermediate levels of urbanization. In introduced populations, altitude and time since bird introduction were positively associated with the number of parasite lineages.
GLOBAL ECOLOGY AND BIOGEOGRAPHY
(2023)
Article
Virology
Alice Latinne, Nguyen Thi Thanh Nga, Nguyen Van Long, Pham Thi Bich Ngoc, Hoang Bich Thuy, Pham Thanh Long, Nguyen Thanh Phuong, Le Tin Vinh Quang, Nguyen Tung, Vu Sinh Nam, Vu Trong Duoc, Nguyen Duc Thinh, Randal Schoepp, Keersten Ricks, Ken K. Inui, Pawin Padungtod, Christine Johnson, Jonna A. K. H. Mazet, Chris E. Walzer, Sarah Olson, Amanda Fine
Summary: A One Health cross-sectoral surveillance approach was used to screen samples from bats, pigs, and humans in Viet Nam for zoonotic viral spillover. The study detected significant viral diversity, including coronaviruses closely related to pig pathogens, in bats roosting at high-risk interfaces. The surveillance also revealed possible previous exposure to filoviruses, bunyaviruses, and flaviviruses in humans living close to bat caves.
Article
Immunology
Tali S. Berman, Maya Weinberg, Kelsey R. Moreno, Gabor A. Czirjak, Yossi Yovel
Summary: This study investigated the changes in gut microbiome (GM) of bats (Rousettus aegyptiacus) during health and disease. The results showed that antigen challenge caused a shift in the composition of the bat GM, which was significantly correlated with haptoglobin concentration and sampling time. The bat GM exhibited high resilience, rapidly regaining the colony's group GM composition.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Microbiology
Geraldine Nouailles, Julia M. Adler, Peter Pennitz, Stefan Peidli, Luiz Gustavo Teixeira Alves, Morris Baumgardt, Judith Bushe, Anne Voss, Alina Langenhagen, Christine Langner, Ricardo Martin Vidal, Fabian Pott, Julia Kazmierski, Aileen Ebenig, Mona V. Lange, Michael D. Muehlebach, Cengiz Goekeri, Szandor Simmons, Na Xing, Azza Abdelgawad, Susanne Herwig, Guenter Cichon, Daniela Niemeyer, Christian Drosten, Christine Goffinet, Markus Landthaler, Nils Bluethgen, Haibo Wu, Martin Witzenrath, Achim D. Gruber, Samantha D. Praktiknjo, Nikolaus Osterrieder, Emanuel Wyler, Dusan Kunec, Jakob Trimpert
Summary: In hamsters, compared the live-attenuated vaccine sCPD9, mRNA vaccine BNT162b2, and adenovirus-vectored vaccine with SARS-CoV-2 challenge, sCPD9 vaccine elicited the strongest immune response, including rapid viral clearance, reduced tissue damage, fast differentiation of pre-plasmablasts, strong systemic and mucosal humoral responses, and rapid recall of memory T cells from lung tissue after heterologous SARS-CoV-2 challenge.
NATURE MICROBIOLOGY
(2023)
Article
Fisheries
Xingxing Wang, Weiwei Zeng, Nikolaus Osterrieder
Summary: Tilapia lake virus (TiLV) is an emerging orthomyxovirus-like pathogen that causes high mortality rates in tilapia and poses a serious threat to the global tilapia industry. While TiLV can infect and replicate in various fish cell lines, its infection and replication in mammalian cells have not been documented until now. This study demonstrates the antiviral activity of mammalian type I interferon against TiLV, suggesting a potential mechanism of TiLV pathogenesis and providing insights for the development of vaccines and antiviral therapies against this important fish pathogen.
Review
Veterinary Sciences
Klaus Osterrieder, David C. Dorman, Brandy A. Burgess, Lutz S. Goehring, Peggy Gross, Claire Neinast, Nicola Pusterla, Gisela Soboll Hussey, David P. Lunn
Summary: This study found that commercial and experimental vaccines minimally reduce the incidence of clinical disease associated with EHV-1 infection.
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2023)
Article
Veterinary Sciences
Ariunbaatar Barkhasbaatar, Martin Gilbert, Amanda E. Fine, Enkhtuvshin Shiilegdamba, Batchuluun Damdinjav, Bayarbaatar Buuveibaatar, Bodisaikhan Khishgee, Christine K. Johnson, Connie Y. H. Leung, Ulaankhuu Ankhanbaatar, Dulam Purevtseren, James M. Tuttle, Jonna A. K. Mazet, Joseph S. Malik Peiris, Losolmaa Jambal, Munkhduuren Shatar, Tuvshintugs Sukhbaatar, Sarah H. Olson
Summary: This study collected a total of 10,222 fecal samples from wild birds in Mongolia between 2009-2013 and 2016-2018, and identified 175 low-pathogenicity avian influenza viruses of 29 subtype combinations. During these time periods, the viruses were more frequently detected in the fall season (August to October) compared with the early summer (April to July). The study demonstrates the use of a cost-effective fecal sampling approach for monitoring avian influenza in wild bird populations and contributes to our understanding of the prevalence and ecology of these viruses in Mongolia, a country with a globally important habitat for large concentrations of migratory water birds.
VETERINARY MEDICINE AND SCIENCE
(2023)
Article
Ecology
Maria Cristina Lorenzi, Franco G. Robles-Guerrero, David Costantini
Summary: Measuring reproductive costs is crucial to understanding sexual conflict and its evolutionary outcomes. In this study, hermaphroditic worms were exposed to different social conditions to measure reproductive costs. It was found that hermaphrodites that invested relatively more in the female function produced fewer eggs but had higher levels of antioxidant protection. This suggests that in the short-term, male competition might be costlier than egg production in terms of regulation of oxidative status.
Article
Biodiversity Conservation
Daniel J. Becker, Jessie M. Merrifield, Csongor I. Vagasi, Gabor A. Czirjak, Peter L. Pap
Summary: Characterizing spatial differences in wildlife immunity is crucial for understanding host defense and disease risks. A study on house sparrows found that birds from Romania have greater inflammatory responses than birds from Egypt. Further investigation is needed to determine the underlying drivers of these differences.
Article
Biology
P. A. Seeber, Z. Palmer, A. Schmidt, A. Chagas, K. Kitagawa, E. Marinova-Wolff, Y. Tafelmaier, L. S. Epp
Summary: This study successfully obtained the mitochondrial genomes of European woolly rhinoceros using coprolites of cave hyenas found in German caves. The results showed genetic differences between European and Siberian woolly rhinoceros populations, and suggested a potential split of populations coinciding with the earliest fossil records of woolly rhinoceros in Europe.