Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters

Non-cell-autonomous disruption of nuclear architecture as a potential cause of COVID-19-induced anosmia

(2022) Marianna Zazhytska et al.   CELL

Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2

(2022) Sam Afkhami et al.   CELL

Neutralization and durability of 2 or 3 doses of the BNT162b2 vaccine against Omicron SARS-CoV-2

(2022) Hongjie Xia et al.   Cell Host & Microbe

Unraveling B cell trajectories at single cell resolution

(2022) Dhakshayini Morgan et al.   TRENDS IN IMMUNOLOGY

Mucosal Vaccines, Sterilizing Immunity, and the Future of SARS-CoV-2 Virulence

(2022) Daniele Focosi et al.   Viruses-Basel

Mucosal immune responses to infection and vaccination in the respiratory tract

(2022) Robert C. Mettelman et al.   IMMUNITY

An intranasal lentiviral booster reinforces the waning mRNA vaccine-induced SARS-CoV-2 immunity that it targets to lung mucosa

(2022) Benjamin Vesin et al.   MOLECULAR THERAPY

Systemic and mucosal IgA responses are variably induced in response to SARS-CoV-2 mRNA vaccination and are associated with protection against subsequent infection

(2022) Salma Sheikh-Mohamed et al.   Mucosal Immunology

SARS-CoV-2 pathogenesis

(2022) Mart M. Lamers et al.   NATURE REVIEWS MICROBIOLOGY

Adenovirus type 5 SARS-CoV-2 vaccines delivered orally or intranasally reduced disease severity and transmission in a hamster model

(2022) Stephanie N. Langel et al.   Science Translational Medicine

Respiratory Mucosal Immunity: Kinetics of Secretory Immunoglobulin A in Sputum and Throat Swabs From COVID-19 Patients and Vaccine Recipients

(2022) Cuiping Ren et al.   Frontiers in Microbiology

Immune responses after omicron infection in triple-vaccinated health-care workers with and without previous SARS-CoV-2 infection

(2022) Kim Blom et al.   LANCET INFECTIOUS DISEASES

Expansion of cytotoxic tissue-resident CD8+ T cells and CCR6+CD161+ CD4+ T cells in the nasal mucosa following mRNA COVID-19 vaccination

(2022) Aloysious Ssemaganda et al.   Nature Communications

Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after TH2-biased immunization

(2022) Aileen Ebenig et al.   Cell Reports

Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses

(2022) Tianyang Mao et al.   SCIENCE

Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells

(2022) Marco Künzli et al.   Science Immunology

Protocol to dissociate healthy and infected murine- and hamster-derived lung tissue for single-cell transcriptome analysis

(2022) Peter Pennitz et al.   STAR Protocols

RNA-sequencing data-driven dissection of human plasma cell differentiation reveals new potential transcription regulators

(2021) Alboukadel Kassambara et al.   LEUKEMIA

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses

(2021) Jackson S. Turner et al.   NATURE

Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine

(2021) Valerie Oberhardt et al.   NATURE

Scalable live-attenuated SARS-CoV-2 vaccine candidate demonstrates preclinical safety and efficacy

(2021) Ying Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19

(2021) Geraldine Nouailles et al.   Nature Communications

An intranasal vaccine durably protects against SARS-CoV-2 variants in mice

(2021) Ahmed O. Hassan et al.   Cell Reports

A single intranasal or intramuscular immunization with chimpanzee adenovirus-vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters

(2021) Traci L. Bricker et al.   Cell Reports

Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding

(2021) Jakob Trimpert et al.   Cell Reports

Deciphering the Role of Humoral and Cellular Immune Responses in Different COVID-19 Vaccines—A Comparison of Vaccine Candidate Genes in Roborovski Dwarf Hamsters

(2021) Jakob Trimpert et al.   Viruses-Basel

Live attenuated virus vaccine protects against SARS-CoV-2 variants of concern B.1.1.7 (Alpha) and B.1.351 (Beta)

(2021) Jakob Trimpert et al.   Science Advances

Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR

(2020) Victor M Corman et al.   Eurosurveillance

Single-cell analysis of olfactory neurogenesis and differentiation in adult humans

(2020) Michael A. Durante et al.   NATURE NEUROSCIENCE

Oil-in-water emulsion adjuvants for pediatric influenza vaccines: a systematic review and meta-analysis

(2020) Yu-Ju Lin et al.   Nature Communications

The Effects of Pre-Existing Antibodies on Live-Attenuated Viral Vaccines

(2020) Darren Z. L. Mok et al.   Viruses-Basel

A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice

(2020) Dorottya Laczkó et al.   IMMUNITY

SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19

(2020) Julian Braun et al.   NATURE

Age-Dependent Progression of SARS-CoV-2 Infection in Syrian Hamsters

(2020) Nikolaus Osterrieder et al.   Viruses-Basel

A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2

(2020) Ahmed O. Hassan et al.   CELL

SARS‐CoV‐2 infection of Chinese hamsters ( Cricetulus griseus ) reproduces COVID‐19 pneumonia in a well‐established small animal model

(2020) Luca D. Bertzbach et al.   Transboundary and Emerging Diseases

Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19

(2020) Guillaume Carissimo et al.   Nature Communications

Mucosal Immunity in COVID-19: A Neglected but Critical Aspect of SARS-CoV-2 Infection

(2020) Michael W. Russell et al.   Frontiers in Immunology

CD4+ resident memory T cells dominate immunosurveillance and orchestrate local recall responses

(2019) Lalit K. Beura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Aging and Senescence in Canine Testes

(2019) Sophie E. Merz et al.   VETERINARY PATHOLOGY

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Attenuation of a very virulent Marek's disease herpesvirus (MDV) by codon pair bias deoptimization

(2018) Kathrin Eschke et al.   PLoS Pathogens

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

Airway Memory CD4 + T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses

(2016) Jincun Zhao et al.   IMMUNITY

Diffusion pseudotime robustly reconstructs lineage branching

(2016) Laleh Haghverdi et al.   NATURE METHODS

Prime-Boost Strategies in Mucosal Immunization Affect Local IgA Production and the Type of Th Response

(2013) Fabio Fiorino et al.   Frontiers in Immunology

Secretory immunity with special reference to the oral cavity

(2013) Per Brandtzaeg   Journal of Oral Microbiology

Rationalizing the development of live attenuated virus vaccines

(2010) Adam S Lauring et al.   NATURE BIOTECHNOLOGY

Virus Attenuation by Genome-Scale Changes in Codon Pair Bias

(2008) J. R. Coleman et al.   SCIENCE