High doses of CRISPR/Cas9 ribonucleoprotein efficiently induce gene knockout with low mosaicism in the hydrozoan Clytia hemisphaerica through microhomology-mediated deletion

A gonad-expressed opsin mediates light-induced spawning in the jellyfish Clytia

(2018) Gonzalo Quiroga Artigas et al.   eLife

CRISPR/Cas9 in Genome Editing and Beyond

(2016) Haifeng Wang et al.   Annual Review of Biochemistry

Gene cassette knock-in in mammalian cells and zygotes by enhanced MMEJ

(2016) Tomomi Aida et al.   BMC GENOMICS

The Heroes of CRISPR

(2016) Eric S. Lander   CELL

CRISPR/Cas9 Mutagenesis Reveals Versatile Roles of Hox Genes in Crustacean Limb Specification and Evolution

(2016) Arnaud Martin et al.   CURRENT BIOLOGY

Hydrozoan insights in animal development and evolution

(2016) Lucas Leclère et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Diving into marine genomics with CRISPR/Cas9 systems

(2016) Tsuyoshi Momose et al.   Marine Genomics

DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks

(2016) Megan van Overbeek et al.   MOLECULAR CELL

Welcome to the CRISPR zoo

(2016) Sara Reardon   NATURE

Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development

(2016) Summer B. Thyme et al.   Cell Reports

53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks

(2016) Josée Guirouilh-Barbat et al.   PLoS Genetics

Deciphering relationship between microhomology and in-frame mutation occurrence in human CRISPR-based gene knockout

(2016) Guohui Chuai et al.   Molecular Therapy-Nucleic Acids

Targeted mutagenesis of aryl hydrocarbon receptor 2a and 2b genes in Atlantic killifish (Fundulus heteroclitus)

(2015) Neelakanteswar Aluru et al.   AQUATIC TOXICOLOGY

Efficient CRISPR-mediated gene targeting and transgene replacement in the beetle Tribolium castaneum

(2015) A. F. Gilles et al.   DEVELOPMENT

CRISPR/Cas9-mediated mutagenesis in the sea lamprey Petromyzon marinus: a powerful tool for understanding ancestral gene functions in vertebrates

(2015) T. Square et al.   DEVELOPMENT

High Efficiency, Homology-Directed Genome Editing in Caenorhabditis elegans Using CRISPR-Cas9 Ribonucleoprotein Complexes

(2015) A. Paix et al.   GENETICS

MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems

(2015) Tetsushi Sakuma et al.   Nature Protocols

Biallelic Gene Targeting in Rice

(2015) Masaki Endo et al.   PLANT PHYSIOLOGY

Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins

(2015) Séverine Ménoret et al.   Scientific Reports

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

Switching on cilia: transcriptional networks regulating ciliogenesis

(2014) S. P. Choksi et al.   DEVELOPMENT

CRISPR/Cas9-mediated gene knockout in the ascidianCiona intestinalis

(2014) Haruka Sasaki et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

CRISPR-Cas systems for editing, regulating and targeting genomes

(2014) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

Microhomology-based choice of Cas9 nuclease target sites

(2014) Sangsu Bae et al.   NATURE METHODS

Easy quantitative assessment of genome editing by sequence trace decomposition

(2014) Eva K. Brinkman et al.   NUCLEIC ACIDS RESEARCH

Efficient Gene Knockout in Goats Using CRISPR/Cas9 System

(2014) Wei Ni et al.   PLoS One

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9

(2014) Shota Nakade et al.   Nature Communications

An endogenous green fluorescent protein-photoprotein pair in Clytia hemisphaerica eggs shows co-targeting to mitochondria and efficient bioluminescence energy transfer

(2014) C. Fourrage et al.   Open Biology

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

(2013) Haoyi Wang et al.   CELL

Biallelic genome modification in F0Xenopus tropicalisembryos using the CRISPR/Cas system

(2013) Ira L. Blitz et al.   GENESIS

Heritable Gene Knockout in Caenorhabditis elegans by Direct Injection of Cas9–sgRNA Ribonucleoproteins

(2013) Seung Woo Cho et al.   GENETICS

A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice

(2013) Cristina Escribano-Díaz et al.   MOLECULAR CELL

Biochemical DSB-repair model for mammalian cells in G1 and early S phases of the cell cycle

(2013) Reza Taleei et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems

(2013) Wei Li et al.   NATURE BIOTECHNOLOGY

Efficient genome editing in zebrafish using a CRISPR-Cas system

(2013) Woong Y Hwang et al.   NATURE BIOTECHNOLOGY

Heritable gene targeting in the mouse and rat using a CRISPR-Cas system

(2013) Dali Li et al.   NATURE BIOTECHNOLOGY

Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system

(2013) Li-En Jao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

53BP1: pro choice in DNA repair

(2013) Michal Zimmermann et al.   TRENDS IN CELL BIOLOGY

A conserved function for Strabismus in establishing planar cell polarity in the ciliated ectoderm during cnidarian larval development

(2012) T. Momose et al.   DEVELOPMENT

Maternally localized germ plasm mRNAs and germ cell/stem cell formation in the cnidarian Clytia

(2012) Lucas Leclère et al.   DEVELOPMENTAL BIOLOGY

Interstitial stem cells in Hydra: multipotency and decision-making

(2012) Charles N. David   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Hydractinia, a pioneering model for stem cell biology and reprogramming somatic cells to pluripotency

(2012) Günter Plickert et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

(2012) G. Gasiunas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Double-Strand Break End Resection and Repair Pathway Choice

(2011) Lorraine S. Symington et al.   Annual Review of Genetics

RFX2 is broadly required for ciliogenesis during vertebrate development

(2011) Mei-I Chung et al.   DEVELOPMENTAL BIOLOGY

RFX2 is essential in the ciliated organ of asymmetry and an RFX2 transgene identifies a population of ciliated cells sufficient for fluid flow

(2011) Brent W. Bisgrove et al.   DEVELOPMENTAL BIOLOGY

Knockout rats generated by embryo microinjection of TALENs

(2011) Laurent Tesson et al.   NATURE BIOTECHNOLOGY

The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

(2010) Josiane E. Garneau et al.   NATURE

Plasticity of Animal Genome Architecture Unmasked by Rapid Evolution of a Pelagic Tunicate

(2010) F. Denoeud et al.   SCIENCE

Bioluminescence in the Ocean: Origins of Biological, Chemical, and Ecological Diversity

(2010) E. A. Widder   SCIENCE

Clytia hemisphaerica: a jellyfish cousin joins the laboratory

(2010) Evelyn Houliston et al.   TRENDS IN GENETICS

Bioluminescence in the Sea

(2009) Steven H.D. Haddock et al.   Annual Review of Marine Science

Differential expression of Rfx1-4 during mouse spermatogenesis

(2009) W. Stephen Kistler et al.   GENE EXPRESSION PATTERNS

CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle

(2009) Maximina H. Yun et al.   NATURE

MMEJ repair of double-strand breaks (director’s cut): deleted sequences and alternative endings

(2008) Mitch McVey et al.   TRENDS IN GENETICS