Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responses

Systems analysis of protective immune responses to RTS,S malaria vaccination in humans

(2017) Dmitri Kazmin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polyfunctional T-Cell Signatures to Predict Protection from Cytomegalovirus after Lung Transplantation

(2016) Laurie D. Snyder et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01BWith Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP

(2016) Tommy Rampling et al.   JOURNAL OF INFECTIOUS DISEASES

Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

(2016) Andrew S Ishizuka et al.   NATURE MEDICINE

Status of vaccine research and development of vaccines for malaria

(2016) Ashley J. Birkett   VACCINE

Identification of Novel Pre-Erythrocytic Malaria Antigen Candidates for Combination Vaccines with Circumsporozoite Protein

(2016) Cate Speake et al.   PLoS One

The public health impact of malaria vaccine RTS,S in malaria endemic Africa: country-specific predictions using 18 month follow-up Phase III data and simulation models

(2015) Melissa A Penny et al.   BMC Medicine

Tailoring a Combination Preerythrocytic Malaria Vaccine

(2015) Karolis Bauza et al.   INFECTION AND IMMUNITY

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

(2015)   LANCET

Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection

(2015) Anders Boyd et al.   PLoS One

Large screen approaches to identify novel malaria vaccine candidates

(2015) D. Huw Davies et al.   VACCINE

Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates

(2015) Rhea J. Longley et al.   Scientific Reports

Genome-based vaccine design: the promise for malaria and other infectious diseases

(2014) Denise L. Doolan et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Immunization with Apical Membrane Antigen 1 Confers Sterile Infection-Blocking Immunity against Plasmodium Sporozoite Challenge in a Rodent Model

(2013) Sophie Schussek et al.   INFECTION AND IMMUNITY

High, Broad, Polyfunctional, and Durable T Cell Immune Responses Induced in Mice by a Novel Hepatitis C Virus (HCV) Vaccine Candidate (MVA-HCV) Based on Modified Vaccinia Virus Ankara Expressing the Nearly Full-Length HCV Genome

(2013) C. E. Gomez et al.   JOURNAL OF VIROLOGY

Malaria vaccine technology roadmap

(2013) Vasee S Moorthy et al.   LANCET

DNA Prime/Adenovirus Boost Malaria Vaccine Encoding P. falciparum CSP and AMA1 Induces Sterile Protection Associated with Cell-Mediated Immunity

(2013) Ilin Chuang et al.   PLoS One

The Relationship between RTS,S Vaccine-Induced Antibodies, CD4+ T Cell Responses and Protection against Plasmodium falciparum Infection

(2013) Michael T. White et al.   PLoS One

Highly Sensitive Quantitative Real-Time PCR for the Detection of Plasmodium Liver-Stage Parasite Burden following Low-Dose Sporozoite Challenge

(2013) Sophie Schussek et al.   PLoS One

Vaccination with Lipid Core Peptides Fails to Induce Epitope-Specific T Cell Responses but Confers Non-Specific Protective Immunity in a Malaria Model

(2012) Simon H. Apte et al.   PLoS One

Phase 1 Study in Malaria Naïve Adults of BSAM2/Alhydrogel®+CPG 7909, a Blood Stage Vaccine against P. falciparum Malaria

(2012) Ruth D. Ellis et al.   PLoS One

A Statistical Interaction between Circumsporozoite Protein-Specific T Cell and Antibody Responses and Risk of Clinical Malaria Episodes following Vaccination with RTS,S/AS01E

(2012) Francis M. Ndungu et al.   PLoS One

High-throughput multi-parameter flow-cytometric analysis from micro-quantities of Plasmodium-infected blood

(2011) Simon H. Apte et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Combining Liver- and Blood-Stage Malaria Viral-Vectored Vaccines: Investigating Mechanisms of CD8+ T Cell Interference

(2011) E. K. Forbes et al.   JOURNAL OF IMMUNOLOGY

Identification of two new protective pre-erythrocytic malaria vaccine antigen candidates

(2011) Keith Limbach et al.   MALARIA JOURNAL

Interferon-γ, a valuable surrogate marker of Plasmodium falciparum pre-erythrocytic stages protective immunity

(2011) Blanca-Liliana Perlaza et al.   MALARIA JOURNAL

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Induction of Plasmodium falciparum-Specific CD4+ T Cells and Memory B Cells in Gabonese Children Vaccinated with RTS,S/AS01E and RTS,S/AS02D

(2011) Selidji T. Agnandji et al.   PLoS One

Protective Immunity Induced with the RTS,S/AS Vaccine Is Associated with IL-2 and TNF-α Producing Effector and Central Memory CD4+ T Cells

(2011) Joanne M. Lumsden et al.   PLoS One

Evaluation of Approaches to Identify the Targets of Cellular Immunity on a Proteome-Wide Scale

(2011) Fernanda C. Cardoso et al.   PLoS One

Longevity and Composition of Cellular Immune Responses Following Experimental Plasmodium falciparum Malaria Infection in Humans

(2011) Anne C. Teirlinck et al.   PLoS Pathogens

Chlamydia muridarum T-Cell Antigens Formulated with the Adjuvant DDA/TDB Induce Immunity against Infection That Correlates with a High Frequency of Gamma Interferon (IFN- )/Tumor Necrosis Factor Alpha and IFN- /Interleukin-17 Double-Positive CD4+ T Cells

(2010) H. Yu et al.   INFECTION AND IMMUNITY

Plasmodium immunomics

(2010) Denise L. Doolan   INTERNATIONAL JOURNAL FOR PARASITOLOGY

A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray

(2010) P. D. Crompton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prime-Boost Immunization with Adenoviral and Modified Vaccinia Virus Ankara Vectors Enhances the Durability and Polyfunctionality of Protective Malaria CD8+ T-Cell Responses

(2009) A. Reyes-Sandoval et al.   INFECTION AND IMMUNITY

Tuberculosis Subunit Vaccination Provides Long-Term Protective Immunity Characterized by Multifunctional CD4 Memory T Cells

(2009) T. Lindenstrom et al.   JOURNAL OF IMMUNOLOGY

Randomized, Double‐Blind, Phase 2a Trial of Falciparum Malaria Vaccines RTS,S/AS01B and RTS,S/AS02A in Malaria‐Naive Adults: Safety, Efficacy, and Immunologic Associates of Protection

(2009) Kent E. Kester et al.   JOURNAL OF INFECTIOUS DISEASES

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Protection against a Malaria Challenge by Sporozoite Inoculation

(2009) Meta Roestenberg et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Immune Epitope Database 2.0

(2009) Randi Vita et al.   NUCLEIC ACIDS RESEARCH

Sterile Protection against Plasmodium knowlesi in Rhesus Monkeys from a Malaria Vaccine: Comparison of Heterologous Prime Boost Strategies

(2009) George Jiang et al.   PLoS One

Plasmodium falciparum apical membrane antigen 1 vaccine elicits multifunctional CD4 cytokine-producing and memory T cells

(2009) Maria Cecilia Huaman et al.   VACCINE

Evaluation of the safety and immunogenicity of Plasmodium falciparum apical membrane antigen 1, merozoite surface protein 1 or RTS,S vaccines with adjuvant system AS02A administered alone or concurrently in rhesus monkeys

(2009) S. Pichyangkul et al.   VACCINE

PlasmoDB: a functional genomic database for malaria parasites

(2008) C. Aurrecoechea et al.   NUCLEIC ACIDS RESEARCH

Evidence of Blood Stage Efficacy with a Virosomal Malaria Vaccine in a Phase IIa Clinical Trial

(2008) Fiona M. Thompson et al.   PLoS One

A combined transcriptome and proteome survey of malaria parasite liver stages

(2008) A. S. Tarun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Profiling humoral immune responses to P. falciparum infection with protein microarrays

(2008) Denise L. Doolan et al.   PROTEOMICS