HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells

Delivery of Therapeutics Targeting the mRNA-Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth

(2016) Yu-Hung Huang et al.   CANCER RESEARCH

HuR Contributes to TRAIL Resistance by Restricting Death Receptor 4 Expression in Pancreatic Cancer Cells

(2016) C. Romeo et al.   MOLECULAR CANCER RESEARCH

IL-24 modulates the high mobility group (HMG) A1/miR222 /AKT signaling in lung cancer cells

(2016) Janani Panneerselvam et al.   Oncotarget

HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy

(2016) Meghna Mehta et al.   Oncotarget

Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis

(2016) Fernando F. Blanco et al.   Oncotarget

Nanosomes carrying doxorubicin exhibit potent anticancer activity against human lung cancer cells

(2016) Akhil Srivastava et al.   Scientific Reports

Folate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migration

(2016) Ranganayaki Muralidharan et al.   JOURNAL OF NANOBIOTECHNOLOGY

Identification and Validation of Novel Small Molecule Disruptors of HuR-mRNA Interaction

(2015) Xiaoqing Wu et al.   ACS Chemical Biology

HuR-targeted nanotherapy in combination with AMD3100 suppresses CXCR4 expression, cell growth, migration and invasion in lung cancer

(2015) R Muralidharan et al.   CANCER GENE THERAPY

Technologies for controlled, local delivery of siRNA

(2015) Samantha M. Sarett et al.   JOURNAL OF CONTROLLED RELEASE

Going beyond the liver: Progress and challenges of targeted delivery of siRNA therapeutics

(2015) Cornelia Lorenzer et al.   JOURNAL OF CONTROLLED RELEASE

The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells

(2015) F F Blanco et al.   ONCOGENE

mTOR-targeted therapy: Differential perturbation to mitochondrial membrane potential and permeability transition pore plays a role in therapeutic response

(2014) Jae Eun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chitosan Coated Polylactic Acid Nanoparticle-Mediated Combinatorial Delivery of Cisplatin and siRNA/Plasmid DNA Chemosensitizes Cisplatin-Resistant Human Ovarian Cancer Cells

(2014) Anish Babu et al.   MOLECULAR PHARMACEUTICS

High Expression of HuR in Cytoplasm, but Not Nuclei, Is Associated with Malignant Aggressiveness and Prognosis in Bladder Cancer

(2013) Yasuyoshi Miyata et al.   PLoS One

Myostatin induces mitochondrial metabolic alteration and typical apoptosis in cancer cells

(2013) Y Liu et al.   Cell Death & Disease

The Oncogenic RNA-Binding Protein Musashi1 Is Regulated by HuR via mRNA Translation and Stability in Glioblastoma Cells

(2012) D. T. Vo et al.   MOLECULAR CANCER RESEARCH

HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium

(2011) T Kurosu et al.   BRITISH JOURNAL OF CANCER

The RNA-Binding Protein HuR Promotes Glioma Growth and Treatment Resistance

(2011) N. Filippova et al.   MOLECULAR CANCER RESEARCH

EGFR-Targeted Hybrid Plasmonic Magnetic Nanoparticles Synergistically Induce Autophagy and Apoptosis in Non-Small Cell Lung Cancer Cells

(2011) Tomohisa Yokoyama et al.   PLoS One

The RNA binding protein HuR differentially regulates unique subsets of mRNAs in estrogen receptor negative and estrogen receptor positive breast cancer

(2010) Robert Calaluce et al.   BMC CANCER

Cytoplasmic accumulation of the RNA binding protein HuR is central to tamoxifen resistance in estrogen receptor positive breast cancer cells

(2010) Christine Hostetter et al.   CANCER BIOLOGY & THERAPY

Inhibitory effect of HuR gene small interfering RNA segment on laryngeal carcinoma Hep-2 cell growth

(2010) Z Shen et al.   JOURNAL OF LARYNGOLOGY AND OTOLOGY

Cytoplasmic HuR expression correlates with angiogenesis, lymphangiogenesis, and poor outcome in lung cancer

(2010) Jun Wang et al.   MEDICAL ONCOLOGY

HuR Knockdown Changes the Oncogenic Potential of Oral Cancer Cells

(2010) W. Kakuguchi et al.   MOLECULAR CANCER RESEARCH

RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation

(2010) D Durie et al.   ONCOGENE

pp32 (ANP32A) Expression Inhibits Pancreatic Cancer Cell Growth and Induces Gemcitabine Resistance by Disrupting HuR Binding to mRNAs

(2010) Timothy K. Williams et al.   PLoS One

Regulation of Bcl-2 Expression by HuR in HL60 Leukemia Cells and A431 Carcinoma Cells

(2009) D. Ishimaru et al.   MOLECULAR CANCER RESEARCH

Stabilization of XIAP mRNA through the RNA binding protein HuR regulated by cellular polyamines

(2009) Xian Zhang et al.   NUCLEIC ACIDS RESEARCH

The Expression of RNA-Binding Protein HuR in Non-Small Cell Lung Cancer Correlates with Vascular Endothelial Growth Factor-C Expression and Lymph Node Metastasis

(2009) Jun Wang et al.   ONCOLOGY

Expression of the embryonic lethal abnormal vision-like protein HuR in human mesothelioma

(2008) Daniela Stoppoloni et al.   CANCER