Polydatin inhibits mast cell-mediated allergic inflammation by targeting PI3K/Akt, MAPK, NF-κB and Nrf2/HO-1 pathways

Ovalbumin-induced allergic inflammation lead to structural alterations in mouse model and protective effects of intranasal curcumin: A comparative study

(2016) Subhashini et al.   ALLERGOLOGIA ET IMMUNOPATHOLOGIA

Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways

(2016) Liangchang Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Potent Anti-inflammatory and Analgesic Actions of the Chloroform Extract of Dendropanax morbifera Mediated by the Nrf2/HO-1 Pathway

(2016) Muhammad Akram et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Induction of Microglial Activation by Mediators Released from Mast Cells

(2016) Xiang Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A new steroidal saponin, furotrilliumoside from Trillium tschonoskii inhibits lipopolysaccharide-induced inflammation in Raw264.7 cells by targeting PI3K/Akt, MARK and Nrf2/HO-1 pathways

(2016) Ting Yan et al.   FITOTERAPIA

Curcumin attenuates quinocetone induced apoptosis and inflammation via the opposite modulation of Nrf2/HO-1 and NF-kB pathway in human hepatocyte L02 cells

(2016) Chongshan Dai et al.   FOOD AND CHEMICAL TOXICOLOGY

Mast cells in human digestive tube in normal and pathological conditions

(2016) Anna Rizzi et al.   IMMUNOLOGY LETTERS

Reversion of Asthmatic Complications and Mast Cell Signalling Pathways in BALB/c Mice Model Using Quercetin Nanocrystals

(2016) Kriti Gupta et al.   Journal of Biomedical Nanotechnology

Mast Cell Degranulation Is Accompanied by the Release of a Selective Subset of Extracellular Vesicles That Contain Mast Cell–Specific Proteases

(2016) Tom Groot Kormelink et al.   JOURNAL OF IMMUNOLOGY

Three Arachidonoylamide Derivatives Inhibit Pro-Inflammatory Genes Expression by Modulating NF-κB and AP1 Activities

(2016) Alex Gregorelli et al.   Medicinal Chemistry

Neuroprotective effects of polydatin against mitochondrial-dependent apoptosis in the rat cerebral cortex following ischemia/reperfusion injury

(2016) Youguang Gao et al.   Molecular Medicine Reports

Effective treatment of polydatin weakens the symptoms of collagen-induced arthritis in mice through its anti-oxidative and anti-inflammatory effects and the activation of MMP-9

(2016) Bo Li et al.   Molecular Medicine Reports

AMPK-Activated Protein Kinase Suppresses Ccr2 Expression by Inhibiting the NF-κB Pathway in RAW264.7 Macrophages

(2016) Fumiaki Kumase et al.   PLoS One

Live Imaging of Immune Responses in Experimental Models of Multiple Sclerosis

(2016) Barbara Rossi et al.   Frontiers in Immunology

Spiraeoside inhibits mast cells activation and IgE-mediated allergic responses by suppressing phospholipase C-γ-mediated signaling

(2015) Jung Kuk Kim et al.   Biochemistry and Cell Biology

The role of individual protein kinase C isoforms in mouse mast cell function and their targeting by the immunomodulatory parasitic worm product, ES-62

(2015) Kara S. Bell et al.   IMMUNOLOGY LETTERS

Sargaquinoic acid attenuates inflammatory responses by regulating NF-κB and Nrf2 pathways in lipopolysaccharide-stimulated RAW 264.7 cells

(2015) Eun-Ji Joung et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Tetraspanin CD151 Is a Negative Regulator of FcεRI-Mediated Mast Cell Activation

(2015) Hiam Abdala-Valencia et al.   JOURNAL OF IMMUNOLOGY

Effect of Chicoric Acid on Mast Cell-Mediated Allergic Inflammation in Vitro and in Vivo

(2015) Na Young Lee et al.   JOURNAL OF NATURAL PRODUCTS

Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells

(2015) Kaipeng Huang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

C-type natriuretic peptide attenuates LPS-induced endothelial activation: involvement of p38, Akt, and NF-κB pathways

(2014) Gan Chen et al.   AMINO ACIDS

Inhibiting mast cell degranulation by HO-1 affects dendritic cell maturation in vitro

(2014) Yuan-yuan Ma et al.   INFLAMMATION RESEARCH

A20 Overexpression Inhibits Lipopolysaccharide-Induced NF-κB Activation, TRAF6 and CD40 Expression in Rat Peritoneal Mesothelial Cells

(2014) Xun-Liang Zou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Polydatin supplementation ameliorates diet-induced development of insulin resistance and hepatic steatosis in rats

(2014) QI ZHANG et al.   Molecular Medicine Reports

Genetic Deletion of Mst1 Alters T Cell Function and Protects against Autoimmunity

(2014) Konstantin V. Salojin et al.   PLoS One

Allergic sensitization: host-immune factors

(2014) Ronald van Ree et al.   Clinical and Translational Allergy

Defining the role of DAG, mitochondrial function, and lipid deposition in palmitate-induced proinflammatory signaling and its counter-modulation by palmitoleate

(2013) Katherine Macrae et al.   JOURNAL OF LIPID RESEARCH

Berberine attenuates bleomycin induced pulmonary toxicity and fibrosis via suppressing NF-κB dependant TGF-β activation: A biphasic experimental study

(2013) Palanivel Chitra et al.   TOXICOLOGY LETTERS

Polydatin attenuated food allergyviastore-operated calcium channels in mast cell

(2013) Bo Yang   WORLD JOURNAL OF GASTROENTEROLOGY

Genome-Wide Association Studies of Allergic Diseases

(2013) Mayumi Tamari et al.   ALLERGOLOGY INTERNATIONAL

Melatonin Improves Bladder Symptoms and May Ameliorate Bladder Damage via Increasing HO-1 in Rats

(2012) Qing-hua Zhang et al.   INFLAMMATION

Polydatin (PD) inhibits IgE-mediated passive cutaneous anaphylaxis in mice by stabilizing mast cells through modulating Ca2+ mobilization

(2012) Meichun Yuan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Allergy to low dose sugammadex

(2011) L. Menéndez-Ozcoidi et al.   ANAESTHESIA

Polydatin modulates inflammation by decreasing NF-κB activation and oxidative stress by increasing Gli1, Ptch1, SOD1 expression and ameliorates blood–brain barrier permeability for its neuroprotective effect in pMCAO rat brain

(2011) Hui Ji et al.   BRAIN RESEARCH BULLETIN

Nuclear factor-erythroid 2-related factor 2 as a chemopreventive target in colorectal cancer

(2011) Constance Lay Lay Saw et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Mast cells and inflammation

(2010) Theoharis C. Theoharides et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease

(2010) Malin von Otter et al.   BMC Medical Genetics

Production of proinflammatory cytokines in the human THP-1 monocyte cell line following induction by Tp0751, a recombinant protein of Treponema pallidum

(2010) ShuangQuan Liu et al.   Science China-Life Sciences

The tyrosine kinase network regulating mast cell activation

(2009) Alasdair M. Gilfillan et al.   IMMUNOLOGICAL REVIEWS

Heme oxygenase-1 mediates the anti-allergic actions of quercetin in rodent mast cells

(2009) Miyoko Matsushima et al.   INFLAMMATION RESEARCH