The open architecture of HD-PTP phosphatase provides new insights into the mechanism of regulation of ESCRT function

Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP

(2017) Deepankar Gahloth et al.   STRUCTURE

Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery

(2017) Liliane Christ et al.   TRENDS IN BIOCHEMICAL SCIENCES

The ESCRT machinery: new roles at new holes

(2016) Y Olmos et al.   CURRENT OPINION IN CELL BIOLOGY

Phosphorylation-Dependent Activation of the ESCRT Function of ALIX in Cytokinetic Abscission and Retroviral Budding

(2016) Sheng Sun et al.   DEVELOPMENTAL CELL

Reverse-topology membrane scission by the ESCRT proteins

(2016) Johannes Schöneberg et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural Study of the HD-PTP Bro1 Domain in a Complex with the Core Region of STAM2, a Subunit of ESCRT-0

(2016) Juhyeon Lee et al.   PLoS One

Structural Basis for Selective Interaction between the ESCRT Regulator HD-PTP and UBAP1

(2016) Deepankar Gahloth et al.   STRUCTURE

A non-canonical ESCRT pathway, including histidine domain phosphotyrosine phosphatase (HD-PTP), is used for down-regulation of virally ubiquitinated MHC class I

(2015) M. D. J. Parkinson et al.   BIOCHEMICAL JOURNAL

Unravelling the pivotal role of Alix in MVB sorting and silencing of the activated EGFR

(2015) Sheng Sun et al.   BIOCHEMICAL JOURNAL

Histidine-domain-containing protein tyrosine phosphatase regulates platelet-derived growth factor receptor intracellular sorting and degradation

(2015) Haisha Ma et al.   CELLULAR SIGNALLING

Conserved Mode of Interaction between Yeast Bro1 Family V Domains and YP(X) n L Motif-Containing Target Proteins

(2015) Yoko Kimura et al.   EUKARYOTIC CELL

ESCRT-III controls nuclear envelope reformation

(2015) Yolanda Olmos et al.   NATURE

Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing

(2015) Marina Vietri et al.   NATURE

Cadherin flexibility provides a key difference between desmosomes and adherens junctions

(2015) Humera Tariq et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An ESCRT module is required for neuron pruning

(2015) Nicolas Loncle et al.   Scientific Reports

Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration

(2015) Dmitri Kharitidi et al.   Cell Reports

The PI3K Class III Complex Promotes Axon Pruning by Downregulating a Ptc-Derived Signal via Endosome-Lysosomal Degradation

(2014) Noa Issman-Zecharya et al.   DEVELOPMENTAL CELL

Ubiquitination in disease pathogenesis and treatment

(2014) Doris Popovic et al.   NATURE MEDICINE

ESCRT Machinery Is Required for Plasma Membrane Repair

(2014) A. J. Jimenez et al.   SCIENCE

Ubiquitin-Dependent Sorting in Endocytosis

(2014) R. C. Piper et al.   Cold Spring Harbor Perspectives in Biology

Recruitment of UBPY and ESCRT Exchange Drive HD-PTP-Dependent Sorting of EGFR to the MVB

(2013) Nazim Ali et al.   CURRENT BIOLOGY

ALIX and the multivesicular endosome: ALIX in Wonderland

(2013) Christin Bissig et al.   TRENDS IN CELL BIOLOGY

Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein

(2012) J. F. Nabhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multivesicular Body Morphogenesis

(2011) Phyllis I. Hanson et al.   Annual Review of Cell and Developmental Biology

Characterizing flexible and intrinsically unstructured biological macromolecules by SAS using the Porod-Debye law

(2011) Robert P. Rambo et al.   BIOPOLYMERS

UBAP1 Is a Component of an Endosome-Specific ESCRT-I Complex that Is Essential for MVB Sorting

(2011) Flavia Stefani et al.   CURRENT BIOLOGY

Microautophagy of Cytosolic Proteins by Late Endosomes

(2011) Ranjit Sahu et al.   DEVELOPMENTAL CELL

Activation of the Retroviral Budding Factor ALIX

(2011) Q. Zhai et al.   JOURNAL OF VIROLOGY

The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release

(2011) Paola Sette et al.   STRUCTURE

Decoding the intrinsic mechanism that prohibits ALIX interaction with ESCRT and viral proteins

(2010) Xi Zhou et al.   BIOCHEMICAL JOURNAL

FoXS: a web server for rapid computation and fitting of SAXS profiles

(2010) D. Schneidman-Duhovny et al.   NUCLEIC ACIDS RESEARCH

A Crescent-Shaped ALIX Dimer Targets ESCRT-III CHMP4 Filaments

(2009) Ricardo Pires et al.   STRUCTURE

The CHMP4b- and Src-docking sites in the Bro1 domain are autoinhibited in the native state of Alix

(2008) Xi Zhou et al.   BIOCHEMICAL JOURNAL

Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release

(2008) J. G. Carlton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Bro1-related protein HD-PTP/PTPN23 is required for endosomal cargo sorting and multivesicular body morphogenesis

(2008) A. Doyotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA