Effector T helper cell populations are elevated in the bone marrow of rheumatoid arthritis patients and correlate with disease severity

Loss of IL-22 inhibits autoantibody formation in collagen-induced arthritis in mice

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Elevated circulating Th17 and follicular helper CD4+T cells in patients with rheumatoid arthritis

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PLZF RegulatesCCR6and Is Critical for the Acquisition and Maintenance of the Th17 Phenotype in Human Cells

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Endogenous IL-22 Plays a Dual Role in Arthritis: Regulation of Established Arthritis via IFN-γ Responses

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Increased Th17 Cell Frequency and Poor Clinical Outcome in Rheumatoid Arthritis Are Associated With a Genetic Variant in theIL4RGene, rs1805010

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Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow

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Increased Serum Interleukin 22 in Patients with Rheumatoid Arthritis and Correlation with Disease Activity

(2012) LAURINDO FERREIRA da ROCHA et al.   JOURNAL OF RHEUMATOLOGY

Increased Frequencies of Th22 Cells as well as Th17 Cells in the Peripheral Blood of Patients with Ankylosing Spondylitis and Rheumatoid Arthritis

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Interleukin 22 serum levels are associated with radiographic progression in rheumatoid arthritis

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Increased expression of interleukin-22 by synovial Th17 cells during late stages of murine experimental arthritis is controlled by interleukin-1 and enhances bone degradation

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Elevated Th22 Cells Correlated with Th17 Cells in Patients with Rheumatoid Arthritis

(2011) Lei Zhang et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Elevated number of recently activated T cells in bone marrow of patients with rheumatoid arthritis: a role for interleukin 15?

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Role of Th17 cells in human autoimmune arthritis

(2010) Jan Leipe et al.   ARTHRITIS AND RHEUMATISM

A novel T cell cytokine, secreted osteoclastogenic factor of activated T cells, induces osteoclast formation in a RANKL-independent manner

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Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice

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Expression of MDC/CCL22 and its receptor CCR4 in rheumatoid arthritis, psoriatic arthritis and osteoarthritis

(2009) Helene Aarslev Flytlie et al.   CYTOKINE

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

(2009) Sara Trifari et al.   NATURE IMMUNOLOGY

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

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Osteoimmunology and the effects of the immune system on bone

(2009) Hiroshi Takayanagi   Nature Reviews Rheumatology

Interleukin-17 and Type 17 Helper T Cells

(2009) Pierre Miossec et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-α, Oncostatin M and response to biologic therapies

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IL-17/Th17 targeting: On the road to prevent chronic destructive arthritis?

(2007) Erik Lubberts   CYTOKINE