NKG2D+CD4+ T Cells Kill Regulatory T Cells in a NKG2D-NKG2D Ligand- Dependent Manner in Systemic Lupus Erythematosus

Aberrant NKG2D expression with IL-17 production of CD4+ T subsets in patients with type 2 diabetes

(2017) Wisitsak Phoksawat et al.   IMMUNOBIOLOGY

Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies

(2016) Amos Gilhar et al.   AUTOIMMUNITY REVIEWS

Interleukin 17 signaling drives Type I Interferon induced proliferative crescentic glomerulonephritis in lupus-prone mice

(2016) Kritika Ramani et al.   CLINICAL IMMUNOLOGY

Anti-NKG2D monoclonal antibody (NNC0142-0002) in active Crohn's disease: a randomised controlled trial

(2016) Matthieu Allez et al.   GUT

Cellular Adjuvant Properties, Direct Cytotoxicity of Re-differentiated Vα24 Invariant NKT-like Cells from Human Induced Pluripotent Stem Cells

(2016) Shuichi Kitayama et al.   Stem Cell Reports

A Phase II study of the efficacy and safety of rontalizumab (rhuMAb interferon-α) in patients with systemic lupus erythematosus (ROSE)

(2015) Kenneth C Kalunian et al.   ANNALS OF THE RHEUMATIC DISEASES

NKG2D expression by CD8+ T cells contributes to GVHD and GVT effects in a murine model of allogeneic HSCT

(2015) M. A. Karimi et al.   BLOOD

Remission of systemic lupus erythematosus disease activity with regulatory cytokine interleukin (IL)-35 in Murphy Roths Large (MRL)/lpr mice

(2015) Z. Cai et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Animal Models of Lupus and Lupus Nephritis

(2015) Yong Du et al.   CURRENT PHARMACEUTICAL DESIGN

Th1/Th2/Th17/Treg cytokine imbalance in systemic lupus erythematosus (SLE) patients: Correlation with disease activity

(2015) Roba M. Talaat et al.   CYTOKINE

NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery

(2015) Roberto Spada et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pathogenesis and targeted treatment of skin injury in SLE

(2015) Guo-Min Deng et al.   Nature Reviews Rheumatology

Effect of NKG2D ligand expression on host immune responses

(2015) Marine Champsaur et al.   IMMUNOLOGICAL REVIEWS

MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells

(2014) Isobel S. Okoye et al.   IMMUNITY

NK Cells Lyse T Regulatory Cells That Expand in Response to an Intracellular Pathogen

(2014) S. Roy et al.   JOURNAL OF IMMUNOLOGY

Treg Cells Are Negatively Correlated with Increased Memory B Cells in Pre-eclampsia While Maintaining Suppressive Function on Autologous B-Cell Proliferation

(2013) Bin Zeng et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Sifalimumab, a Human Anti-Interferon-α Monoclonal Antibody, in Systemic Lupus Erythematosus: A Phase I Randomized, Controlled, Dose-Escalation Study

(2013) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

Management of immune cytopenias in patients with systemic lupus erythematosus — Old and new

(2013) Kam Newman et al.   AUTOIMMUNITY REVIEWS

Assessment of intracellular cytokines and regulatory cells in patients with autoimmune diseases and primary immunodeficiencies — Novel tool for diagnostics and patient follow-up

(2013) Liv T. Osnes et al.   AUTOIMMUNITY REVIEWS

Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity

(2012) G. Pietra et al.   CANCER RESEARCH

NKG2D blockade facilitates diabetes prevention by antigen-specific Tregs in a virus-induced model of diabetes

(2012) Tom L. Van Belle et al.   JOURNAL OF AUTOIMMUNITY

Anti-IFN- /  Receptor Antibody Treatment Ameliorates Disease in Lupus-Predisposed Mice

(2012) R. Baccala et al.   JOURNAL OF IMMUNOLOGY

Cell surface expression of activating receptors and co-receptors on peripheral blood NK cells in systemic autoimmune diseases

(2012) I Puxeddu et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

TGF-β1 Down-Regulation of NKG2D/DAP10 and 2B4/SAP Expression on Human NK Cells Contributes to HBV Persistence

(2012) Cheng Sun et al.   PLoS Pathogens

Excessive interleukin-15 transpresentation endows NKG2D+CD4+ T cells with innate-like capacity to lyse vascular endothelium in granulomatosis with polyangiitis (Wegener's)

(2011) Mathilde de Menthon et al.   ARTHRITIS AND RHEUMATISM

Blockade of NKG2D ameliorates disease in mice with collagen-induced arthritis: A potential pathogenic role in chronic inflammatory arthritis

(2011) Anna K. Andersson et al.   ARTHRITIS AND RHEUMATISM

Decreased frequencies of CD4+CD25+Foxp3+cells and the potent CD103+subset in peripheral lymph nodes correlate with autoimmune disease predisposition in some strains of mice

(2011) Colleen F. Tucker et al.   AUTOIMMUNITY

Natural Killer Cells From Children With Type 1 Diabetes Have Defects in NKG2D-Dependent Function and Signaling

(2011) Huilian Qin et al.   DIABETES

Regulatory T-cells in systemic lupus erythematosus and rheumatoid arthritis

(2011) Konstantia-Maria Chavele et al.   FEBS LETTERS

Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity

(2011) Emilie Mamessier et al.   JOURNAL OF CLINICAL INVESTIGATION

The interferon-α signature of systemic lupus erythematosus

(2010) G. Obermoser et al.   LUPUS

Genome-wide association study in alopecia areata implicates both innate and adaptive immunity

(2010) Lynn Petukhova et al.   NATURE

Regulatory T Cells Suppress Natural Killer Cells during Plasmid DNA Vaccination in Mice, Blunting the CD8+ T Cell Immune Response by the Cytokine TGFβ

(2010) Kwesi Frimpong-Boateng et al.   PLoS One

Assay of T- and NK-cell subsets and the expression of NKG2A and NKG2D in patients with new-onset systemic lupus erythematosus

(2009) Wen-Xian Li et al.   CLINICAL RHEUMATOLOGY

Normally occurring NKG2D+CD4+T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus

(2009) Zhenpeng Dai et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chimeric NKG2D Expressing T Cells Eliminate Immunosuppression and Activate Immunity within the Ovarian Tumor Microenvironment

(2009) A. Barber et al.   JOURNAL OF IMMUNOLOGY

Mutual activation of CD4+ T cells and monocytes mediated by NKG2D–MIC interaction requires IFN-gamma production in systemic lupus erythematosus

(2009) Di Yang et al.   MOLECULAR IMMUNOLOGY

CD4+CD25+ regulatory T cells in human lupus erythematosus

(2008) Annegret Kuhn et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Expansion of circulating NKG2D+ effector memory T-cells and expression of NKG2D-ligand MIC in granulomaous lesions in Wegener's granulomatosis

(2008) Dorin Capraru et al.   CLINICAL IMMUNOLOGY

Regulatory T cells as central regulators of both autoimmunity and B cell malignancy in New Zealand Black mice

(2008) Brian J. Scaglione et al.   JOURNAL OF AUTOIMMUNITY

Altered frequency and migration capacity of CD4+CD25+ regulatory T cells in systemic lupus erythematosus

(2008) H.-Y. Lee et al.   RHEUMATOLOGY