Indicators of responsiveness to immune checkpoint inhibitors

Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma

(2016) Willy Hugo et al.   CELL

Greater Than the Sum of Parts: Complexity of the Dynamic Epigenome

(2016) Alexey A. Soshnev et al.   MOLECULAR CELL

An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation

(2016) George P Souroullas et al.   NATURE MEDICINE

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

A phase I trial of panobinostat (LBH589) in patients with metastatic melanoma

(2016) Nageatte Ibrahim et al.   Cancer Medicine

Unknown

(2016)   Pigment Cell & Melanoma Research

Induction of Resistance to BRAF Inhibitor Is Associated with the Inability of Spry2 to Inhibit BRAF-V600E Activity in BRAF Mutant Cells

(2015) Jun-Ho Ahn et al.   Biomolecules & Therapeutics

PD-1/PD-L1 inhibitors

(2015) Joel Sunshine et al.   CURRENT OPINION IN PHARMACOLOGY

Epigenetic regulation in human melanoma: past and future

(2015) Debina Sarkar et al.   Epigenetics

Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma

(2015) Deepanwita Sengupta et al.   MOLECULAR & CELLULAR PROTEOMICS

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

(2015) Stefani Spranger et al.   NATURE

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

(2015) James Larkin et al.   NEW ENGLAND JOURNAL OF MEDICINE

The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors

(2015) Daniel Zingg et al.   Nature Communications

Melanoma

(2015) Dirk Schadendorf et al.   Nature Reviews Disease Primers

Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchymal transition in human melanoma

(2015) Aparna Jayachandran et al.   Oncotarget

Epigenetic plasticity: A central regulator of epithelial-to-mesenchymal transition in cancer

(2015) Upasana Bedi et al.   Oncotarget

CD63 Tetraspanin Is a Negative Driver of Epithelial-to-Mesenchymal Transition in Human Melanoma Cells

(2014) Antonella Lupia et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

PD-1 blockade induces responses by inhibiting adaptive immune resistance

(2014) Paul C. Tumeh et al.   NATURE

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

(2014) Alexandra Snyder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

(2013) Omid Hamid et al.   NEW ENGLAND JOURNAL OF MEDICINE

Heterogeneity of expression of epithelial–mesenchymal transition markers in melanocytes and melanoma cell lines

(2013) Ji Eun Kim et al.   Frontiers in Genetics

The chemoattractant chemerin suppresses melanoma by recruiting natural killer cell antitumor defenses

(2012) Russell K. Pachynski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NADPH Oxidase 1 Overexpression Enhances Invasion via Matrix Metalloproteinase-2 and Epithelial–Mesenchymal Transition in Melanoma Cells

(2012) Feng Liu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

CXCL17 Expression by Tumor Cells Recruits CD11b+Gr1highF4/80− Cells and Promotes Tumor Progression

(2012) Aya Matsui et al.   PLoS One

A quantitative proteomic analysis of FFPE melanoma

(2011) Stephanie Byrum et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

A new understanding in the epidemiology of melanoma

(2010) Esther Erdei et al.   Expert Review of Anticancer Therapy

Immunotherapy for Melanoma: Current Status and Perspectives

(2010) Doru T. Alexandrescu et al.   JOURNAL OF IMMUNOTHERAPY

Evaluation of molecular markers of mesenchymal phenotype in melanoma

(2010) Leann M. Mikesh et al.   MELANOMA RESEARCH

Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment

(2009) H. Harlin et al.   CANCER RESEARCH

Guidelines for the Evaluation of Immune Therapy Activity in Solid Tumors: Immune-Related Response Criteria

(2009) J. D. Wolchok et al.   CLINICAL CANCER RESEARCH

Prognostic Significance of Cadherin-Based Adhesion Molecules in Cutaneous Malignant Melanoma

(2008) G. M. Kreizenbeck et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

In vivo Switching of Human Melanoma Cells between Proliferative and Invasive States

(2008) K. S. Hoek et al.   CANCER RESEARCH