BIM-23A760 influences key functional endpoints in pituitary adenomas and normal pituitaries: molecular mechanisms underlying the differential response in adenomas

Truncated somatostatin receptor variant sst5TMD4 confers aggressive features (proliferation, invasion and reduced octreotide response) to somatotropinomas

(2015) Raúl M. Luque et al.   CANCER LETTERS

Melatonin Regulates Somatotrope and Lactotrope Function Through Common and Distinct Signaling Pathways in Cultured Primary Pituitary Cells From Female Primates

(2015) Alejandro Ibáñez-Costa et al.   ENDOCRINOLOGY

In1-ghrelin splicing variant is overexpressed in pituitary adenomas and increases their aggressive features

(2015) Alejandro Ibáñez-Costa et al.   Scientific Reports

Obestatin Plays an Opposite Role in the Regulation of Pituitary Somatotrope and Corticotrope Function in Female Primates and Male/Female Mice

(2014) Raúl M. Luque et al.   ENDOCRINOLOGY

The Truncated Isoform of Somatostatin Receptor5 (sst5TMD4) Is Associated with Poorly Differentiated Thyroid Cancer

(2014) Manel Puig-Domingo et al.   PLoS One

Somatostatin receptors: From signaling to clinical practice

(2013) Marily Theodoropoulou et al.   FRONTIERS IN NEUROENDOCRINOLOGY

A Cellular and Molecular Basis for the Selective Desmopressin-Induced ACTH Release in Cushing Disease Patients: Key Role of AVPR1b Receptor and Potential Therapeutic Implications

(2013) R. M. Luque et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Neurocognitive Function in Acromegaly after Surgical Resection of GH-Secreting Adenoma versus Naïve Acromegaly

(2013) Juan Francisco Martín-Rodríguez et al.   PLoS One

Somatostatin analogs and chimeric somatostatin–dopamine molecules differentially regulate human growth hormone and prolactin gene expression and secretion in vitro

(2012) Anna Gruszka et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Somatostatin receptor sst2 gene transfer in human prolactinomas in vitro: Impact on sensitivity to dopamine, somatostatin and dopastatin, in the control of prolactin secretion

(2012) Thomas Cuny et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Clinical consequences of Cushing’s syndrome

(2012) Elena Valassi et al.   Pituitary

Balance between somatostatin and D2 receptor expression drives TSH-secreting adenoma response to somatostatin analogues and dopastatins

(2011) Federico Gatto et al.   CLINICAL ENDOCRINOLOGY

Resistance to Somatostatin Analogs in Acromegaly

(2011) Annamaria Colao et al.   ENDOCRINE REVIEWS

Homologous and Heterologousin VitroRegulation of Pituitary Receptors for Somatostatin, Growth Hormone (GH)-Releasing Hormone, and Ghrelin in a Nonhuman Primate (Papio anubis)

(2011) Jose Córdoba-Chacón et al.   ENDOCRINOLOGY

Somatostatin-Dopamine Chimeras: A Novel Approach to Treatment of Neuroendocrine Tumors

(2011) M. Culler   HORMONE AND METABOLIC RESEARCH

Somatostatin Dramatically Stimulates Growth Hormone Release from Primate Somatotrophs Acting at Low Doses Via Somatostatin Receptor 5 and Cyclic AMP

(2011) J. Córdoba-Chacón et al.   JOURNAL OF NEUROENDOCRINOLOGY

Medical treatment of prolactinomas

(2011) Annamaria Colao et al.   Nature Reviews Endocrinology

The new truncated somatostatin receptor variant sst5TMD4 is associated to poor prognosis in breast cancer and increases malignancy in MCF-7 cells

(2011) M Durán-Prado et al.   ONCOGENE

Somatostatin and its receptors contribute in a tissue-specific manner to the sex-dependent metabolic (fed/fasting) control of growth hormone axis in mice

(2010) José Córdoba-Chacón et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Somatostatin and its receptors from fish to mammals

(2010) Manuel D. Gahete et al.   Annals of the New York Academy of Sciences

Evidence of Cognitive and Neurophysiological Impairment in Patients with Untreated Naive Acromegaly

(2010) José Leon-Carrion et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A Potential Inhibitory Role for the New Truncated Variant of Somatostatin Receptor 5, sst5TMD4, in Pituitary Adenomas Poorly Responsive to Somatostatin Analogs

(2010) Mario Durán-Prado et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Somatostatin and dopamine receptor interaction in prostate and lung cancer cell lines

(2010) M Arvigo et al.   JOURNAL OF ENDOCRINOLOGY

Pasireotide Alone or with Cabergoline and Ketoconazole in Cushing's Disease

(2010) Richard A. Feelders et al.   NEW ENGLAND JOURNAL OF MEDICINE

The dopamine–somatostatin chimeric compound BIM-23A760 exerts antiproliferative and cytotoxic effects in human non-functioning pituitary tumors by activating ERK1/2 and p38 pathways

(2009) Erika Peverelli et al.   CANCER LETTERS

Expression Analysis of Dopamine Receptor Subtypes in Normal Human Pituitaries, Nonfunctioning Pituitary Adenomas and Somatotropinomas, and the Association between Dopamine and Somatostatin Receptors with Clinical Response to Octreotide-LAR in Acromegaly

(2009) Leonardo Vieira Neto et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Identification and Characterization of Two Novel Truncated but Functional Isoforms of the Somatostatin Receptor Subtype 5 Differentially Present in Pituitary Tumors

(2009) Mario Durán-Prado et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Efficacy of a dopamine-somatostatin chimeric molecule, BIM-23A760, in the control of cell growth from primary cultures of human non-functioning pituitary adenomas: a multi-center study

(2008) T. Florio et al.   ENDOCRINE-RELATED CANCER

Somatostatinergic ligands in dopamine-sensitive and -resistant prolactinomas

(2008) Alessandra Fusco et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Selective agonism in somatostatin receptor signaling and regulation

(2007) Agnes Schonbrunn   MOLECULAR AND CELLULAR ENDOCRINOLOGY