High glucose upregulates BACE1-mediated Aβ production through ROS-dependent HIF-1α and LXRα/ABCA1-regulated lipid raft reorganization in SK-N-MC cells
出版年份 2016 全文链接
标题
High glucose upregulates BACE1-mediated Aβ production through ROS-dependent HIF-1α and LXRα/ABCA1-regulated lipid raft reorganization in SK-N-MC cells
作者
关键词
-
出版物
Scientific Reports
Volume 6, Issue 1, Pages -
出版商
Springer Nature
发表日期
2016-11-10
DOI
10.1038/srep36746
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Activation of Protein Phosphatase 2B and Hyperphosphorylation of Tau in Alzheimer's Disease
- (2018) Wei Qian et al. JOURNAL OF ALZHEIMERS DISEASE
- Plasma Membrane Injury Depends on Bilayer Lipid Composition in Alzheimer's Disease
- (2018) Elisa Evangelisti et al. JOURNAL OF ALZHEIMERS DISEASE
- Memantine Inhibits Calpain-Mediated Truncation of GSK-3 Induced by NMDA: Implications in Alzheimer's Disease
- (2017) Paloma Goñi-Oliver et al. JOURNAL OF ALZHEIMERS DISEASE
- PP2A Regulates Tau Phosphorylation Directly and also Indirectly via Activating GSK-3β
- (2017) Wei Qian et al. JOURNAL OF ALZHEIMERS DISEASE
- Altered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer’s disease mouse model
- (2016) V Frazzini et al. Cell Death & Disease
- Effect of High Glucose Levels on Amyloid β Production in Retinas of Spontaneous Diabetes Mellitus Otsuka Long-Evans Tokushima Fatty Rats
- (2015) Noriaki Nagai et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Hyperglycemia modulates extracellular amyloid-β concentrations and neuronal activity in vivo
- (2015) Shannon L. Macauley et al. JOURNAL OF CLINICAL INVESTIGATION
- Oxygen-glucose deprivation regulates BACE1 expression through induction of autophagy in Neuro-2a/APP695 cells
- (2015) Xiao-jiang Sun et al. Neural Regeneration Research
- Diabetes and Alzheimer Disease, Two Overlapping Pathologies with the Same Background: Oxidative Stress
- (2015) Sergio Rosales-Corral et al. Oxidative Medicine and Cellular Longevity
- The roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer disease
- (2015) Naoyuki Sato et al. Frontiers in Aging Neuroscience
- Dietary regulation of PI3K/AKT/GSK-3β pathway in Alzheimer’s disease
- (2014) Yasuko Kitagishi et al. Alzheimers Research & Therapy
- BACE1 inhibitor drugs in clinical trials for Alzheimer’s disease
- (2014) Robert Vassar Alzheimers Research & Therapy
- Cleavage of GSK-3β by calpain counteracts the inhibitory effect of Ser9 phosphorylation on GSK-3β activity induced by H2O2
- (2013) Ye Feng et al. JOURNAL OF NEUROCHEMISTRY
- High Glucose Promotes Aβ Production by Inhibiting APP Degradation
- (2013) Yi Yang et al. PLoS One
- Transcriptional and post-transcriptional regulation of β-secretase
- (2012) Elena Tamagno et al. IUBMB LIFE
- BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer’s disease
- (2012) Linda Chami et al. Molecular Neurodegeneration
- Transcription of Liver X Receptor Is Down-Regulated by 15-Deoxy-Δ12,14-Prostaglandin J2 through Oxidative Stress in Human Neutrophils
- (2012) Gonzalo Alba et al. PLoS One
- Amyloid Precursor Protein Processing and Alzheimer's Disease
- (2011) Richard J. O'Brien et al. Annual Review of Neuroscience
- Rapamycin pre-treatment abrogates Tumour Necrosis Factor-α down-regulatory effects on LXR-α and PXR mRNA expression via inhibition of c-Jun N-terminal kinase 1 activation in HepG2 cells
- (2011) Choy-Hoong Chew et al. ELECTRONIC JOURNAL OF BIOTECHNOLOGY
- Liver X Receptor-Retinoid X Receptor (LXR-RXR) Heterodimer Cistrome Reveals Coordination of LXR and AP1 Signaling in Keratinocytes
- (2011) Qi Shen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- APP processing in Alzheimer's disease
- (2011) Yun-wu Zhang et al. Molecular Brain
- Diabetes mellitus and Alzheimer's disease: shared pathology and treatment?
- (2010) Kawser Akter et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Diabetes and Insulin in Regulation of Brain Cholesterol Metabolism
- (2010) Ryo Suzuki et al. Cell Metabolism
- Genetic connections between neurological disorders and cholesterol metabolism
- (2010) Ingemar Björkhem et al. JOURNAL OF LIPID RESEARCH
- Treatment of Erectile Dysfunction in the Obese Type 2 Diabetic ZDF Rat with Adipose Tissue-Derived Stem Cells
- (2009) Maurice M. Garcia et al. Journal of Sexual Medicine
- Liver X Receptor Ligands Suppress Ubiquitination and Degradation of LXRα by Displacing BARD1/BRCA1
- (2009) Kang Ho Kim et al. MOLECULAR ENDOCRINOLOGY
- Cell Signaling and Nuclear Receptors: New Opportunities for Molecular Pharmaceuticals in Liver Disease
- (2007) Jeff L. Staudinger et al. MOLECULAR PHARMACEUTICS
- Glucose neurotoxicity
- (2007) David R. Tomlinson et al. NATURE REVIEWS NEUROSCIENCE
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