Overexpression of soluble RAGE in mesenchymal stem cells enhances their immunoregulatory potential for cellular therapy in autoimmune arthritis

HMGB1 Enhances the AGE-Induced Expression of CTGF and TGF-� via RAGE-Dependent Signaling in Renal Tubular Epithelial Cells

(2015) Meichu Cheng et al.   AMERICAN JOURNAL OF NEPHROLOGY

Necrotic cell-derived high mobility group box 1 attracts antigen-presenting cells but inhibits hepatocyte growth factor-mediated tropism of mesenchymal stem cells for apoptotic cell death

(2015) S Vogel et al.   CELL DEATH AND DIFFERENTIATION

Immunoregulatory Effects of Mesenchymal Stem Cell-Derived Extracellular Vesicles on T Lymphocytes

(2015) Andrea Del Fattore et al.   CELL TRANSPLANTATION

Human Adipose Tissue-Derived Mesenchymal Stem Cells Abrogate Plasmablast Formation and Induce Regulatory B Cells Independently of T Helper Cells

(2015) M. Franquesa et al.   STEM CELLS

Human Bone Marrow-Derived Mesenchymal Stromal Cells Differentially Inhibit Cytokine Production by Peripheral Blood Monocytes Subpopulations and Myeloid Dendritic Cells

(2015) Paula Laranjeira et al.   Stem Cells International

Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis

(2014) Shipeng Dang et al.   Autophagy

Human mesenchymal stem cell-derived microvesicles modulate T cell response to islet antigen glutamic acid decarboxylase in patients with type 1 diabetes

(2014) Enrica Favaro et al.   DIABETOLOGIA

Metformin Attenuates Experimental Autoimmune Arthritis through Reciprocal Regulation of Th17/Treg Balance and Osteoclastogenesis

(2014) Hye-Jin Son et al.   MEDIATORS OF INFLAMMATION

Red Ginseng Extract Ameliorates Autoimmune Arthritis via Regulation of STAT3 Pathway, Th17/Treg Balance, and Osteoclastogenesis in Mice and Human

(2014) JooYeon Jhun et al.   MEDIATORS OF INFLAMMATION

TREG-cell therapies for autoimmune rheumatic diseases

(2014) Makoto Miyara et al.   Nature Reviews Rheumatology

EGCG Attenuates Autoimmune Arthritis by Inhibition of STAT3 and HIF-1α with Th17/Treg Control

(2014) Eun-Ji Yang et al.   PLoS One

Mesenchymal stem cells, autoimmunity and rheumatoid arthritis

(2014) J. J. El-Jawhari et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Rheumatoid arthritis pathophysiology: update on emerging cytokine and cytokine-associated cell targets

(2014) D. E. Furst et al.   RHEUMATOLOGY

Human Umbilical Cord-Derived Mesenchymal Stem Cells Utilize Activin-A to Suppress Interferon-γ Production by Natural Killer Cells

(2014) Debanjana Chatterjee et al.   Frontiers in Immunology

Immunobiology of mesenchymal stem cells

(2013) S Ma et al.   CELL DEATH AND DIFFERENTIATION

HGF Mediates the Anti-inflammatory Effects of PRP on Injured Tendons

(2013) Jianying Zhang et al.   PLoS One

Th17 cells and IL-17 A—Focus on immunopathogenesis and immunotherapeutics

(2013) Wim B. van den Berg et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Mesenchymal Stem Cells Induce an Inflammatory Response After Intravenous Infusion

(2013) Martin J. Hoogduijn et al.   STEM CELLS AND DEVELOPMENT

Mesenchymal Stem Cells Migration Homing and Tracking

(2013) Abhishek Sohni et al.   Stem Cells International

Mesenchymal stem cells are conditionally therapeutic in preclinical models of rheumatoid arthritis

(2012) Anastasia Papadopoulou et al.   ANNALS OF THE RHEUMATIC DISEASES

Allogeneic mesenchymal stem cell treatment alleviates experimental and clinical Sjogren syndrome

(2012) J. Xu et al.   BLOOD

Coordinated time-dependent modulation of AMPK/Akt/mTOR signaling and autophagy controls osteogenic differentiation of human mesenchymal stem cells

(2012) Aleksandar Pantovic et al.   BONE

CCR2-Dependent Recruitment of Macrophages by Tumor-Educated Mesenchymal Stromal Cells Promotes Tumor Development and Is Mimicked by TNFα

(2012) Guangwen Ren et al.   Cell Stem Cell

HMGB1: A multifunctional alarmin driving autoimmune and inflammatory disease

(2012) Helena Erlandsson Harris et al.   Nature Reviews Rheumatology

Autophagy Activation: A Novel Mechanism of Atorvastatin to Protect Mesenchymal Stem Cells from Hypoxia and Serum Deprivation via AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Pathway

(2012) Qian Zhang et al.   STEM CELLS AND DEVELOPMENT

Regulation and Function of Autophagy during Cell Survival and Cell Death

(2012) G. Das et al.   Cold Spring Harbor Perspectives in Biology

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

(2011) Ulf Andersson et al.   Annual Review of Immunology

Expanded Adipose-Derived Stem Cells for the Treatment of Complex Perianal Fistula

(2011) Damian Garcia-Olmo et al.   DISEASES OF THE COLON & RECTUM

Disturbed Th17/Treg balance in patients with rheumatoid arthritis

(2011) Qian Niu et al.   RHEUMATOLOGY INTERNATIONAL

Mesenchymal stem cells for the treatment of systemic lupus erythematosus: is the cure for connective tissue diseases within connective tissue?

(2011) Flavio A Carrion et al.   Stem Cell Research & Therapy

Protective targeting of high mobility group box chromosomal protein 1 in a spontaneous arthritis model

(2010) Therese Östberg et al.   ARTHRITIS AND RHEUMATISM

Role of Th17 cells in human autoimmune arthritis

(2010) Jan Leipe et al.   ARTHRITIS AND RHEUMATISM

Soluble RAGE: Therapy and biomarker in unraveling the RAGE axis in chronic disease and aging

(2010) Shi Fang Yan et al.   BIOCHEMICAL PHARMACOLOGY

Beyond immunosuppression: reconsidering indoleamine 2,3-dioxygenase as a pathogenic element of chronic inflammation

(2010) Alexander J Muller et al.   Immunotherapy

Mesenchymal Stem Cells Inhibit Human Th17 Cell Differentiation and Function and Induce a T Regulatory Cell Phenotype

(2010) S. Ghannam et al.   JOURNAL OF IMMUNOLOGY

A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an Immunosuppressive MSC2 Phenotype

(2010) Ruth S. Waterman et al.   PLoS One

Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T cell proliferation and collagen-induced arthritis

(2010) Evelien Schurgers et al.   ARTHRITIS RESEARCH & THERAPY

Receptor for advanced glycation end-products (RAGE) is an indicator of direct lung injury in models of experimental lung injury

(2009) Xiao Su et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells

(2009) Manuel A. González et al.   ARTHRITIS AND RHEUMATISM

RAGE: therapeutic target and biomarker of the inflammatory response-the evidence mounts

(2009) Ravichandran Ramasamy et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Efficacy and safety of certolizumab pegol plus methotrexate in active rheumatoid arthritis: the RAPID 2 study. A randomised controlled trial

(2008) J Smolen et al.   ANNALS OF THE RHEUMATIC DISEASES

Golimumab, a human antibody to tumour necrosis factor   given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD Study

(2008) E C Keystone et al.   ANNALS OF THE RHEUMATIC DISEASES

Interleukin-1 drives pathogenic Th17 cells during spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice

(2008) Marije I. Koenders et al.   ARTHRITIS AND RHEUMATISM

Mesenchymal stem cells overexpressing interleukin-10 attenuate collagen-induced arthritis in mice

(2008) J.-J. Choi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Inciting inflammation: the RAGE about tumor promotion: Figure 1.

(2008) Michael Dougan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis

(2008) F. Flores-Borja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allogeneic mesenchymal stem cell and mesenchymal stem cell-differentiated chondrocyte suppress the responses of type II collagen-reactive T cells in rheumatoid arthritis.

(2007) Z. H. Zheng et al.   RHEUMATOLOGY