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Beneficial protective effect of pramipexole on light-induced retinal damage in mice

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Is mitochondrial generation of reactive oxygen species a trigger for autophagy?

(2014) Yongqiang Chen et al.   Autophagy

Salvianolic acid A protects RPE cells against oxidative stress through activation of Nrf2/HO-1 signaling

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Epigallocatechin-gallate (EGCG) regulates autophagy in human retinal pigment epithelial cells: A potential role for reducing UVB light-induced retinal damage

(2013) Chao-Peng Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Alpha-melanocyte stimulating hormone protects retinal pigment epithelium cells from oxidative stress through activation of melanocortin 1 receptor–Akt–mTOR signaling

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Ultraviolet (UV) and Hydrogen Peroxide Activate Ceramide-ER Stress-AMPK Signaling Axis to Promote Retinal Pigment Epithelium (RPE) Cell Apoptosis

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Mechanisms of age-related macular degeneration and therapeutic opportunities

(2013) Menno van Lookeren Campagne et al.   JOURNAL OF PATHOLOGY

Pseudomonas aeruginosa Pyocyanin Activates NRF2-ARE-Mediated Transcriptional Response via the ROS-EGFR-PI3K-AKT/MEK-ERK MAP Kinase Signaling in Pulmonary Epithelial Cells

(2013) Ying Xu et al.   PLoS One

Ginsenoside Rg-1 Protects Retinal Pigment Epithelium (RPE) Cells from Cobalt Chloride (CoCl2) and Hypoxia Assaults

(2013) Ke-ran Li et al.   PLoS One

Nrf2-mediated redox signaling in arsenic carcinogenesis: a review

(2012) Dona Sinha et al.   ARCHIVES OF TOXICOLOGY

Apo-8′-lycopenal Induces Expression of HO-1 and NQO-1 via the ERK/p38-Nrf2-ARE Pathway in Human HepG2 Cells

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Rapamycin sensitive mTOR activation mediates nerve growth factor (NGF) induced cell migration and pro-survival effects against hydrogen peroxide in retinal pigment epithelial cells

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Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells

(2011) Yoon-Jin Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Stabilization of Nrf2 Protein by D3T Provides Protection against Ethanol-Induced Apoptosis in PC12 Cells

(2011) Jian Dong et al.   PLoS One

Antioxidant-induced modification of INrf2 cysteine 151 and PKC-δ-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance

(2009) Suryakant K. Niture et al.   JOURNAL OF CELL SCIENCE

Low-dose X-irradiation promotes mineralization of fracture callus in a rat model

(2008) Xiao Zhong Zhou et al.   ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY

Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H-1,2-dithiole-3-thione

(2008) Francesc X. Soriano et al.   JOURNAL OF NEUROCHEMISTRY

Dithiolethiones for cancer chemoprevention: where do we stand?

(2008) Y. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Molecular mechanisms of Nrf2-mediated antioxidant response

(2008) Wenge Li et al.   MOLECULAR CARCINOGENESIS

Drug discovery targeting apoptosis

(2008)   NATURE REVIEWS DRUG DISCOVERY

Apoptosis: a clinical perspective

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