Thrombospondin-4 reduces binding affinity of [3H]-gabapentin to calcium-channel α2δ-1-subunit but does not interact with α2δ-1 on the cell-surface when co-expressed

Structure of the voltage-gated calcium channel Cav1.1 complex

(2015) J. Wu et al.   SCIENCE

Anticonvulsant activity of pregabalin in the maximal electroshock-induced seizure assay in α2δ1 (R217A) and α2δ2 (R279A) mouse mutants

(2014) Susan Lotarski et al.   EPILEPSY RESEARCH

Painful nerve injury upregulates thrombospondin-4 expression in dorsal root ganglia

(2014) Bin Pan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Members of the thrombospondin gene family bind stromal interaction molecule 1 and regulate calcium channel activity

(2014) Mark Duquette et al.   MATRIX BIOLOGY

Functional exofacially tagged N-type calcium channels elucidate the interaction with auxiliary  2 -1 subunits

(2014) J. S. Cassidy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical, Target, and Bioactive Properties of Allosteric Modulation

(2014) Gerard J. P. van Westen et al.   PLoS Computational Biology

Input-output relations in biological systems: measurement, information and the Hill equation

(2013) Steven A Frank   Biology Direct

Differential Control of Thrombospondin over Synaptic Glycine and AMPA Receptors in Spinal Cord Neurons

(2013) L. Hennekinne et al.   JOURNAL OF NEUROSCIENCE

Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4

(2013) Eric J. Benner et al.   NATURE

Differential upregulation in DRG neurons of an α2δ-1 splice variant with a lower affinity for gabapentin after peripheral sensory nerve injury

(2013) Beatrice Lana et al.   PAIN

Chronic pregabalin inhibits synaptic transmission between rat dorsal root ganglion and dorsal horn neurons in culture

(2012) Janek Hendrich et al.   Channels

Calcium Currents Are Enhanced by α2δ-1 Lacking Its Membrane Anchor

(2012) Ivan Kadurin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thrombospondin-4 Contributes to Spinal Sensitization and Neuropathic Pain States

(2012) D.-S. Kim et al.   JOURNAL OF NEUROSCIENCE

Erratum: Calcium channel auxiliary α2δ and β subunits: trafficking and one step beyond

(2012) Annette C. Dolphin   NATURE REVIEWS NEUROSCIENCE

Neuronal low-density lipoprotein receptor-related protein 1 binds and endocytoses prion fibrils via receptor cluster 4

(2010) A. Jen et al.   JOURNAL OF CELL SCIENCE

The  2  subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function

(2010) A. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Receptor-associated protein (RAP) has two high-affinity binding sites for the low-density lipoprotein receptor-related protein (LRP): consequences for the chaperone functions of RAP

(2009) Jan K. Jensen et al.   BIOCHEMICAL JOURNAL

Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

(2009) Çagla Eroglu et al.   CELL

The Increased Trafficking of the Calcium Channel Subunit  2 -1 to Presynaptic Terminals in Neuropathic Pain Is Inhibited by the  2  Ligand Pregabalin

(2009) C. S. Bauer et al.   JOURNAL OF NEUROSCIENCE

Presynaptic α2δ-3 is required for synaptic morphogenesis independent of its Ca2+-channel functions

(2009) Peri T Kurshan et al.   NATURE NEUROSCIENCE

LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein

(2008) C. J. Parkyn et al.   JOURNAL OF CELL SCIENCE

Mutations in a Drosophila  2  Voltage-Gated Calcium Channel Subunit Reveal a Crucial Synaptic Function

(2008) D. K. Dickman et al.   JOURNAL OF NEUROSCIENCE

Pharmacological disruption of calcium channel trafficking by the  2  ligand gabapentin

(2008) J. Hendrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA