Mechanism of impaired microtubule-dependent peroxisome trafficking and oxidative stress in SPAST-mutated cells from patients with Hereditary Spastic Paraplegia

Hereditary Spastic Paraplegia: Beyond Clinical Phenotypes toward a Unified Pattern of Central Nervous System Damage

(2015) Federica Agosta et al.   RADIOLOGY

Teaching the fundamentals of electron transfer reactions in mitochondria and the production and detection of reactive oxygen species

(2015) Ryan J. Mailloux   Redox Biology

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons

(2014) S. Havlicek et al.   HUMAN MOLECULAR GENETICS

Revisiting the neuropathogenesis of Zellweger syndrome

(2014) Denis I. Crane   NEUROCHEMISTRY INTERNATIONAL

Making connections: interorganelle contacts orchestrate mitochondrial behavior

(2014) Till Klecker et al.   TRENDS IN CELL BIOLOGY

Low dose tubulin-binding drugs rescue peroxisome trafficking deficit in patient-derived stem cells in Hereditary Spastic Paraplegia

(2014) Y. Fan et al.   Biology Open

Peroxisomal metabolism and oxidative stress

(2013) Marcus Nordgren et al.   BIOCHIMIE

Cell death and diseases related to oxidative stress:4-hydroxynonenal (HNE) in the balance

(2013) S Dalleau et al.   CELL DEATH AND DIFFERENTIATION

Mitochondria are targets for peroxisome-derived oxidative stress in cultured mammalian cells

(2013) Bo Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

The biogenesis protein PEX14 is an optimal marker for the identification and localization of peroxisomes in different cell types, tissues, and species in morphological studies

(2013) Phillip Grant et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Peroxisomes: The neuropathological consequences of peroxisomal dysfunction in the developing brain

(2013) Denis S. Barry et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Axonal transport deficits and neurodegenerative diseases

(2013) Stéphanie Millecamps et al.   NATURE REVIEWS NEUROSCIENCE

Loss of Spastin Function Results in Disease-Specific Axonal Defects in Human Pluripotent Stem Cell-Based Models of Hereditary Spastic Paraplegia

(2013) Kyle R. Denton et al.   STEM CELLS

A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations

(2012) G. Abrahamsen et al.   Disease Models & Mechanisms

Microtubule-targeting drugs rescue axonal swellings in cortical neurons from spastin knockout mice

(2012) C. Fassier et al.   Disease Models & Mechanisms

SPASTmutations in Australian patients with hereditary spastic paraplegia

(2012) H. Vandebona et al.   INTERNAL MEDICINE JOURNAL

Role of peroxisomes in ROS/RNS-metabolism: Implications for human disease

(2011) Marc Fransen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Disease-specific, neurosphere-derived cells as models for brain disorders

(2010) N. Matigian et al.   Disease Models & Mechanisms

Axonal integrity in the absence of functional peroxisomes from projection neurons and astrocytes

(2010) Astrid Bottelbergs et al.   GLIA

Specific pattern of early white-matter changes in pure hereditary spastic paraplegia

(2010) Thomas Duning et al.   MOVEMENT DISORDERS

Peroxisomes Are Oxidative Organelles

(2009) Vasily D. Antonenkov et al.   ANTIOXIDANTS & REDOX SIGNALING

Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients

(2009) Paul R. Kasher et al.   JOURNAL OF NEUROCHEMISTRY

Peroxisome Dynamics in Cultured Mammalian Cells

(2009) Sofie J. Huybrechts et al.   TRAFFIC

Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms

(2008) Sara Salinas et al.   LANCET NEUROLOGY