Diastereoselective synthesis of spiro[cyclopropane-1,3′-indolin]-2′-ones through metal-free cyclopropanation using tosylhydrazone salts

Synthesis of CF3-Containing 3,3′-Cyclopropyl Spirooxindoles by Sequential [3 + 2] Cycloaddition/Ring Contraction of Ylideneoxindoles with 2,2,2-Trifluorodiazoethane

(2014) Tian-Ren Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly diastereoselective synthesis of spiro[cyclopropane-1,3′-indolin]-2′-ones via catalyst-free cyclopropanation using ethyl diazoacetate

(2014) Ram Awatar Maurya et al.   TETRAHEDRON

Rapid Access to Novel 1,2,3-Triazolo-Heterocyclic Scaffolds via Tandem Knoevenagel Condensation/Azide–Alkyne 1,3-Dipolar Cycloaddition Reaction in One Pot

(2014) Ram Awatar Maurya et al.   ACS Combinatorial Science

Regio- and stereoselective synthesis of novel spiropyrrolidines through 1,3-dipolar cycloaddition reactions of azomethine ylides and 2-styrylquinazolin-4(3H)-ones

(2014) Ram Awatar Maurya et al.   RSC Advances

Continuous flow synthesis of toxic ethyl diazoacetate for utilization in an integrated microfluidic system

(2013) Ram Awatar Maurya et al.   GREEN CHEMISTRY

Continuous Flow Generation and Reactions of Anhydrous Diazomethane Using a Teflon AF-2400 Tube-in-Tube Reactor

(2013) Federica Mastronardi et al.   ORGANIC LETTERS

Molecular diversity of cycloaddition reactions of the functionalized pyridinium salts with 3-phenacylideneoxindoles

(2013) Qin Fu et al.   TETRAHEDRON

Catalyst-free stereoselective cyclopropanation of electron deficient alkenes with ethyl diazoacetate

(2013) Ram Awatar Maurya et al.   RSC Advances

One Pot, Two Phases: Iron-Catalyzed Cyclopropanation with In Situ Generated Diazomethane

(2012) Johannes Kaschel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and anticancer activity of heteroaromatic linked 4β-amido podophyllotoxins as apoptotic inducing agents

(2012) Ahmed Kamal et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Intermolecular Metal-Free Cyclopropanation of Alkenes Using Tosylhydrazones

(2012) José Barluenga et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Insights into the Structural Determinants Required for High-Affinity Binding of Chiral Cyclopropane-Containing Ligands to α4β2-Nicotinic Acetylcholine Receptors: An Integrated Approach to Behaviorally Active Nicotinic Ligands

(2012) Han-Kun Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Conformational Restriction Approach to β-Secretase (BACE1) Inhibitors: Effect of a Cyclopropane Ring To Induce an Alternative Binding Mode

(2012) Shuji Yonezawa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Iron-Catalyzed Cyclopropanation in 6 M KOH with in Situ Generation of Diazomethane

(2012) B. Morandi et al.   SCIENCE

Highly stereoselective cyclopropanation of glycals with cyclic diazoamides: a facile synthesis of spirooxindolyl sugar derivatives

(2012) B.V. Subba Reddy et al.   TETRAHEDRON LETTERS

Continuous In Situ Generation, Separation, and Reaction of Diazomethane in a Dual-Channel Microreactor

(2011) Ram Awatar Maurya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetic Organocatalytic 1,3-Dipolar Cycloaddition of Azomethine Ylide to Methyl 2-(2-Nitrophenyl)acrylate for the Synthesis of Diastereoisomers of Spirotryprostatin A

(2011) Mou-Nuo Cheng et al.   ORGANIC LETTERS

Design and synthesis of spirotryprostatin-inspired diketopiperazine systems from prolyl spirooxoindolethiazolidine derivatives

(2010) Alessia Bertamino et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Stereospecific and highly stereoselective cyclopropanation reactions promoted by samarium

(2010) José M. Concellón et al.   CHEMICAL SOCIETY REVIEWS

Regioselective Synthesis of Novel Spiropyrrolidines and Spirothiapyrrolizidines Through Multicomponent 1,3-Dipolar Cycloaddition Reaction of Azomethine Ylides

(2010) Hai Liu et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products

(2010) Andrey P. Antonchick et al.   Nature Chemistry

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

Welwitindolinone C synthetic studies. Construction of the welwitindolinone carbon skeleton via a transannular nitrone cycloaddition

(2010) David B. Freeman et al.   TETRAHEDRON

Exceptional Selectivity in Cyclopropanation Reactions Catalyzed by Chiral Cobalt(II)-Porphyrin Catalysts

(2009) Michael P. Doyle   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-Catalyzed Olefin Cyclopropanation with Ethyl Diazoacetate: Control of the Diastereoselectivity

(2009) Ana Caballero et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

From Nature to Drug Discovery: The Indole Scaffold as a ‘Privileged Structure’

(2009) Fernando de Sa Alves et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Design, Synthesis, and SAR of New Pyrrole-Oxindole Progesterone Receptor Modulators Leading to 5-(7-Fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348)

(2008) Andrew Fensome et al.   JOURNAL OF MEDICINAL CHEMISTRY