Increased abundance of translation machinery in stem cell–derived neural progenitor cells from four schizophrenia patients

3,4-Methylenedioxymethamphetamine facilitates fear extinction learning

(2015) M B Young et al.   Translational Psychiatry

Cellular Differences in Protein Synthesis Regulate Tissue Homeostasis

(2014) Michael Buszczak et al.   CELL

Modeling a Genetic Risk for Schizophrenia in iPSCs and Mice Reveals Neural Stem Cell Deficits Associated with Adherens Junctions and Polarity

(2014) Ki-Jun Yoon et al.   Cell Stem Cell

Ribosomal DNA transcription in the dorsal raphe nucleus is increased in residual but not in paranoid schizophrenia

(2014) Marta Krzyżanowska et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Proteomic and genomic evidence implicates the postsynaptic density in schizophrenia

(2014) M Föcking et al.   MOLECULAR PSYCHIATRY

De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability

(2014) S E McCarthy et al.   MOLECULAR PSYCHIATRY

Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia

(2014) K Brennand et al.   MOLECULAR PSYCHIATRY

Copy number variation in schizophrenia in Sweden

(2014) J P Szatkiewicz et al.   MOLECULAR PSYCHIATRY

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Synaptic dysregulation in a human iPS cell model of mental disorders

(2014) Zhexing Wen et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Roles of Heat Shock Factor 1 in Neuronal Response to Fetal Environmental Risks and Its Relevance to Brain Disorders

(2014) Kazue Hashimoto-Torii et al.   NEURON

Human iPSC Neurons Display Activity-Dependent Neurotransmitter Secretion: Aberrant Catecholamine Levels in Schizophrenia Neurons

(2014) Vivian Hook et al.   Stem Cell Reports

Modeling Hippocampal Neurogenesis Using Human Pluripotent Stem Cells

(2014) Diana Xuan Yu et al.   Stem Cell Reports

Analysis of copy number variations at 15 schizophrenia-associated loci

(2013) Elliott Rees et al.   BRITISH JOURNAL OF PSYCHIATRY

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

Global Transcriptional and Translational Repression in Human-Embryonic-Stem-Cell-Derived Rett Syndrome Neurons

(2013) Yun Li et al.   Cell Stem Cell

The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth

(2013) Lachlan A. Jolly et al.   HUMAN MOLECULAR GENETICS

Is the mTOR-signalling cascade disrupted in Schizophrenia?

(2013) Anand Gururajan et al.   JOURNAL OF NEUROCHEMISTRY

Reelin, an extracellular matrix protein linked to early onset psychiatric diseases, drives postnatal development of the prefrontal cortex via GluN2B-NMDARs and the mTOR pathway

(2013) J Iafrati et al.   MOLECULAR PSYCHIATRY

Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients

(2013) O Robicsek et al.   MOLECULAR PSYCHIATRY

Activity-dependent neuronal signalling and autism spectrum disorder

(2013) Daniel H. Ebert et al.   NATURE

mTOR Inhibition Ameliorates Cognitive and Affective Deficits Caused by Disc1 Knockdown in Adult-Born Dentate Granule Neurons

(2013) Miou Zhou et al.   NEURON

CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation

(2013) Silvia De Rubeis et al.   NEURON

Dysfunction of the Ubiquitin Proteasome and Ubiquitin-Like Systems in Schizophrenia

(2013) María D Rubio et al.   NEUROPSYCHOPHARMACOLOGY

Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction

(2013) D. T. Balu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus

(2013) Jane A. English et al.   Frontiers in Genetics

DISC1 and the aggresome

(2012) Talia Atkin et al.   Autophagy

Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers

(2012) I.-M. Wang et al.   Molecular Systems Biology

A unifying model for mTORC1-mediated regulation of mRNA translation

(2012) Carson C. Thoreen et al.   NATURE

An epigenetic framework for neurodevelopmental disorders: From pathogenesis to potential therapy

(2012) Mark J. Millan   NEUROPHARMACOLOGY

Transcriptome Sequencing Revealed Significant Alteration of Cortical Promoter Usage and Splicing in Schizophrenia

(2012) Jing Qin Wu et al.   PLoS One

miRNA Regulons Associated with Synaptic Function

(2012) Maria Paschou et al.   PLoS One

Genome-wide ribosome profiling reveals complex translational regulation in response to oxidative stress

(2012) M. V. Gerashchenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications

(2012) N C Carty et al.   Translational Psychiatry

Defining the nature of human pluripotent stem cell progeny

(2011) Michaela Patterson et al.   CELL RESEARCH

Altered Oxygen Metabolism Associated to Neurogenesis of Induced Pluripotent Stem Cells Derived from a Schizophrenic Patient

(2011) Bruna Da Silveira Paulsen et al.   CELL TRANSPLANTATION

Modelling schizophrenia using human induced pluripotent stem cells

(2011) Kristen J. Brennand et al.   NATURE

Confirmed rare copy number variants implicate novel genes in schizophrenia

(2010) Gloria W.C. Tam et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions

(2010) Nina C. Hubner et al.   JOURNAL OF CELL BIOLOGY

Automated analysis of neuronal morphology, synapse number and synaptic recruitment

(2010) Sabine K. Schmitz et al.   JOURNAL OF NEUROSCIENCE METHODS

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Use of high content image analysis to detect chemical-induced changes in synaptogenesis in vitro

(2010) Joshua A. Harrill et al.   TOXICOLOGY IN VITRO

Fidelity at the Molecular Level: Lessons from Protein Synthesis

(2009) Hani S. Zaher et al.   CELL

Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia

(2009) Daniel Martins-de-Souza et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Schizophrenia is associated with an increase in cortical microRNA biogenesis

(2009) N J Beveridge et al.   MOLECULAR PSYCHIATRY

DISC1 Regulates New Neuron Development in the Adult Brain via Modulation of AKT-mTOR Signaling through KIAA1212

(2009) Ju Young Kim et al.   NEURON

Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types

(2008) Joseph P. Doyle et al.   CELL

A Hierarchical Network Controls Protein Translation during Murine Embryonic Stem Cell Self-Renewal and Differentiation

(2008) Prabha Sampath et al.   Cell Stem Cell

Genetics of gene expression and its effect on disease

(2008) Valur Emilsson et al.   NATURE

Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks

(2008) Jun Zhu et al.   NATURE GENETICS

Promoter-Wide Hypermethylation of the Ribosomal RNA Gene Promoter in the Suicide Brain

(2008) Patrick O. McGowan et al.   PLoS One

Epigenetic principles and mechanisms underlying nervous system functions in health and disease

(2008) M MEHLER   PROGRESS IN NEUROBIOLOGY